Épaisseur des fibres nerveuses rétiniennes péripapillaires (RNFL) et volume maculaire dans l’amblyopie chez les enfants et les adultes

Quoc, E. Bui; Delepine, B.; Tran, Thi Ha Chau

doi:10.1016/j.jfo.2009.06.002

Cited by 20 publications

(2 citation statements)

References 17 publications

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“…make healthy comparisons between the studies mentioned above and the present study almost impossible. 30 , 31 In the current study, there was no significant difference in mean macular thickness between the amblyopic and non-amblyopic eyes in patients with myopia or hyperopia ( Table 1 ). Previous studies reported conflicting results of macular thickness measurements from OCT in eyes with strabismic and anisometropic amblyopia.…”

Section: Discussionmentioning

confidence: 45%

“… 27 , 28 On the other hand, there are three studies conducted using OCT that suggest RNFL thickness may be greater in eyes with refractive amblyopia. 1 , 30 , 31 In one of these studies, Yen et al 30 evaluated 38 patients with unilateral amblyopia. Among them, 20 patients had amblyopia with strabismus and 18 had refractive amblyopia without strabismus.…”

Section: Discussionmentioning

confidence: 99%

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Retina and Optic Disc Characteristics in Amblyopic and Non-amblyopic Eyes of Patients with Myopic or Hyperopic Anisometropia

Ekim

2017

tjo

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Objectives:To compare retinal and optic disc characteristics between amblyopic and non-amblyopic eyes in patients with myopic and hyperopic anisometropia measured with optical coherence tomography (OCT).Materials and Methods:Patients with myopic (25 patients: 17 female, 8 male; median age 27 years, range 16-40 years) and hyperopic (31 patients: 19 female, 12 male; median age 20 years, range 13-41 years) anisometropic amblyopia were included. Eye examination included determination of best-corrected visual acuity (BCVA) with a Snellen chart, measurement of manifest and cycloplegic refraction after pupillary dilation, alternate cover testing, globe movement evaluation, A-scan biometry for axial length, biomicroscopy, fundus examination, and OCT scanning. Main outcome measures were spherical equivalence, BCVA, axial length, retinal nerve fiber layer (RNFL) thickness, macular thickness, macular volume, and optic disc area.Results:In both myopic and hyperopic patients, the absolute value of the mean spherical equivalence was significantly greater in the amblyopic than non-amblyopic eyes, and the mean BCVA was significantly less in the amblyopic than the non-amblyopic eyes. In both myopic and hyperopic patients, there were no significant differences in mean RNFL thickness, macular thickness, macular volume, axial length, or optic disc area between amblyopic and non-amblyopic eyes.Conclusion:The amblyopic process may have no significant effect on the RNFL, macula, or optic disc. Further studies with more patients, including postmortem studies, may clarify the retinal, histopathologic, and anatomic differences between amblyopic and non-amblyopic eyes.

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Section: Discussionmentioning

confidence: 45%

Section: Discussionmentioning

confidence: 99%

Retina and Optic Disc Characteristics in Amblyopic and Non-amblyopic Eyes of Patients with Myopic or Hyperopic Anisometropia

Ekim

2017

tjo

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Quadrantal macular retinal thickness changes in strabismus subjects with abnormal binocular vision development

Oka

Yamashita

Ono³

et al. 2012

Jpn J Ophthalmol

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Macular and retinal nerve fiber thickness in recovered and persistent amblyopia

2015

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The aim of this study was to investigate the presence of increased macular or retinal nerve fiber layer thickness (RNFLT) in amblyopic eyes, find if the increased macular or RNFLT is related to the lack of response in amblyopic eyes, and to explore whether the increased central macular thickness (CMT) in amblyopic eyes is purely related to the hyperopia. This is a prospective descriptive study. CMT and peripapillary RNFLT were measured by spectral-domain optical coherence tomography to evaluate 60 patients with unilateral-treated amblyopia (median age 11.00 year). Patients were divided into two groups: 33 patients in recovered amblyopia group and 27 patients in persistent amblyopia group. The mean CMT in the recovered group was 247.31 (±23.4) versus 246.8 (±32.7) µm (p = 0.95) for the persistent group. The mean peripapillary RNFLT was 99.13 (±12.1) versus 99.9 (±14.9) µm (p = 0.85) for the persistent group. In anisometropic amblyopia, there was no significant difference in CMT and RNFLT in either group. Also there was no relation between the type of refractive error and CMT or RNFLT. There was no significant difference in CMT and RNFLT in amblyopic eyes for both the recovered amblyopia group and the persistent amblyopia group to explain the lack of response in persistent amblyopic eyes. Additionally there was no relation between the type of refractive error and CMT or peripapillary RNFLT.

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Épaisseur des fibres nerveuses rétiniennes péripapillaires (RNFL) et volume maculaire dans l’amblyopie chez les enfants et les adultes

Cited by 20 publications

References 17 publications

Retina and Optic Disc Characteristics in Amblyopic and Non-amblyopic Eyes of Patients with Myopic or Hyperopic Anisometropia

Retina and Optic Disc Characteristics in Amblyopic and Non-amblyopic Eyes of Patients with Myopic or Hyperopic Anisometropia

Quadrantal macular retinal thickness changes in strabismus subjects with abnormal binocular vision development

Macular and retinal nerve fiber thickness in recovered and persistent amblyopia

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