Eosinophilic pustular folliculitis. Report of two cases with a review of the Japanese literature

Takematsu, Hideaki; Nakamura, Koichiro; Igarashi, Minoru; Tagami, Hachiro

doi:10.1001/archderm.121.7.917

Cited by 50 publications

(55 citation statements)

References 12 publications

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“…In contrast, fewer than 50% of patients with Ofuji disease note persistent pruritus, 20% have palm or sole involvement, and most have a leukocytosis. 9 The etiology of HIV-EF is currently unknown. Bacterial, fungal, and viral culture results are generally nega- tive.…”

Section: Commentmentioning

confidence: 99%

Eosinophilic Folliculitis in 2 HIV-Positive Women

Hayes¹,

Hille²,

Goldberg³

2004

Arch Dermatol

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Section: Commentmentioning

confidence: 99%

Eosinophilic Folliculitis in 2 HIV-Positive Women

Hayes¹,

Hille²,

Goldberg³

2004

Arch Dermatol

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“…Histopathologic examination revealed eosinophilic follicu lar abscesses. Leukocytosis with peripheral eosinophilia was detected in more than 50% of cases [8].…”

Section: Discussionmentioning

confidence: 98%

“…EPF seems to be rare in children [8][9][10][11][12][13][14][15][16][17]. The majority of cases diagnosed as infantile EPF were children below 1 year of age, with a male predominance (table 1).…”

Section: Discussionmentioning

confidence: 99%

“…In more advanced ages (from 4 to 9 years) [8,14,15], EPF usually bears a clinical picture similar to the 'classical' Ofuji's disease (papulopustules with annular polycyclic array on seborrheic areas) and could probably be consid ered as the pediatric counterpart of the adult form of EPF (table 2).…”

Section: Discussionmentioning

confidence: 99%

“…It usually affects adults and is clinically characterized by recurrent crops of sterile and pruritic papulopustules grouped in an annular or polycyclic pattern involving preferably the seborrheic areas. Histopathologic examination reveals eosinophilic follicular abscesses [1][2][3][4][5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

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Infantile Eosinophilic Pustular Folliculitis

García‐Patos¹,

Pujol²,

Moragas³

1994

Dermatology

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Background: Eosinophilic pustular folliculitis (EPF) is a cutaneous inflammatory follicular disorder of unknown etiology. The diagnosis is established on the basis of clinical and histopathologic features. In only a few instances has EPF been described in children. Objective and Methods: We describe the clinical and histopathologic features of a recurrent follicular eosinophilic pustular eruption involving the scalp in 2 children. Previously reported cases of EPF in childhood below 14 years of age are reviewed. Results: Two patients (9-month-old and 6-month-old boys) presented recurrent crops of follicular pustules on the scalp of 4 and 5 months’ evolution. The lesions resolved spontaneously without scarring. Histopathologic examination revealed an acute follicular inflammatory infiltrate with abundant eosinophils. Scraping from the lesions showed abundant eosinophils in 1 case. A peripheral eosinophilia was also detected in both patients. Conclusion: EPF in children below 1 year of age seems to represent a unique disorder bearing distinctive clinical (constant involvement of the scalp), evolutive (self-healing recurrent crops) and prognostic (the lesions may last until 3 years of age) features. A possible relationship between this disorder and other idiopathic pustular dermatoses of early childhood (especially with infantile acropustulosis) is suggested.

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Human Immunodeficiency Virus-Associated Eosinophilic Folliculitis

Rosenthal

LeBoit²,

Klumpp³

et al. 1991

Arch Dermatol

169

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We studied 13 patients with human immunodeficiency virus (HIV) infection and a chronic pruritic folliculitis that was unresponsive to systemic treatment with bactericidal anti-staphylococcal antibiotics. The skin eruption was characterized by multiple urticarial follicular papules scattered on the trunk (100%), the head and neck (85%), and the proximal aspect of the extremities (62%). Absolute peripheral eosinophil counts were increased in six of 13 patients; a relative peripheral eosinophilia was present in 10 of 13 patients. Serum IgE levels were elevated in all seven patients tested (range, 88 to 9050 IU). Histopathologic features included a folliculitis with eosinophils. Pathogenic bacteria were not consistently found by routine bacterial skin cultures, cultures of skin biopsy specimens, or histopathologic evaluation. CD4 counts were decreased in all of the 12 patients tested (less than 300 cells per cubic millimeter) and were below 250 cells per cubic millimeter in 10 patients. A clinical response was noted to astemizole, to ultraviolet light in the B range, and to topical clobetasol propionate. These observations demonstrate that HIV-associated eosinophilic folliculitis is a unique HIV-related cutaneous disorder that is characterized by a culture-negative, chronic, pruritic folliculitis and a characteristic histopathologic picture. Of special importance, because it is associated with CD4 counts of less than 250 to 300 cells per cubic millimeter, eosinophilic folliculitis appears to be an important clinical marker of HIV infection and, particularly, of patients at increased risk of developing opportunistic infections. We suggest that the term eosinophilic pustular folliculitis (Ofuji's disease), previously used to describe this dermatosis in HIV-infected patients, should be discarded.

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Eosinophilic pustular folliculitis. Report of two cases with a review of the Japanese literature

Cited by 50 publications

References 12 publications

Eosinophilic Folliculitis in 2 HIV-Positive Women

Eosinophilic Folliculitis in 2 HIV-Positive Women

Infantile Eosinophilic Pustular Folliculitis

Human Immunodeficiency Virus-Associated Eosinophilic Folliculitis

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