Eosinophilic Cystitis

Goldstein, Michael H.

doi:10.1016/s0022-5347(17)61417-4

Cited by 34 publications

(30 citation statements)

References 9 publications

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“…We collected 81 articles from the international literature containing one or more cases of patients with EC [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82]. A total of 153 patients were mentioned in these articles.…”

Section: Methodsmentioning

confidence: 99%

“…In some patients a mass is palpable during examination of the lower abdomen or digital rectal examination. This was the case in 15 patients [11, 31, 32, 33, 42, 43, 45, 50, 54, 58, 62, 63, 65, 66, 76]. In 2 patients a previously unknown prostatic enlargement was detected [46, 59].…”

Section: Physical Examinationmentioning

confidence: 99%

“…This mechanism may explain the chronicity and recurrence of EC in some patients. Although several kinds of food and contact allergens (condoms, spermatocidal jelly, vaginal tampons) have been named in focal allergic disease of the bladder [29, 32], a relationship to EC has never been proven. Bladder carcinoma was detected in 17 patients, but in 12 patients the causative factor seemed to be the intravesical instillation of mitomycin C [30, 40, 68]or thiotepa [20].…”

Section: Etiologymentioning

confidence: 99%

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Diagnosis and Management of Eosinophilic Cystitis

Ouden¹

2000

European Urology

120

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Section: Methodsmentioning

confidence: 99%

Section: Physical Examinationmentioning

confidence: 99%

Section: Etiologymentioning

confidence: 99%

See 1 more Smart Citation

Diagnosis and Management of Eosinophilic Cystitis

Ouden¹

2000

European Urology

120

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“…Several reports have been published since 1960 [1][2][3][4][5][6][7][8] with only a few cases in children. 10 -16 The disease has been reported in patients with a history of vesical injury and chronic vesical irritation, surgery, 14,17 parasitosis, 11,18,19 allergy to food and drugs, 3,17,20 -23 tuberculous cystitis, 24 malignancies, 25,26 and other conditions.…”

Section: Discussionmentioning

confidence: 99%

“…Eosinophilic cystitis has a broad spectrum of clinical and pathologic manifestations, ranging from mild inflammatory cystitis to severe chronic or recurrent relentless inflammation. [3][4][5][6][7][8] This disorder eventually can progress to a complete fibrosis of the urinary bladder with secondary involvement of the rest of the urinary tract, resulting in obstructive nephropathy with variable degrees of renal insufficiency. [3][4][5][6][7][8][9] We report a child who had severe progressive eosinophilic cystitis and did not respond to high-dose corticosteroid therapy and specific therapy for toxocariasis.…”

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confidence: 99%

Eosinophilic Cystitis in a 4-Year-Old Boy: Successful Long-Term Treatment With Cyclosporin A

et al. 2001

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ABSTRACT. A 4-year-old Jewish boy presented with dysuria, urinary dribbling, increased urinary frequency, and new onset of diurnal enuresis. An infiltrating solid mass involving the entire bladder wall was found. Biopsy revealed "tumor-forming" eosinophilic cystitis, a rare bladder lesion of unclear cause. Antitoxocariasis treatment was unsuccessful. High-dose corticosteroids failed. The child's clinical condition and bladder sonographic findings continued to deteriorate. Treatment with cyclosporin A was given for 8 months, with a complete clinical, radiologic, and histopathologic cure and no side effects. Two years of follow-up showed a complete recovery. Pediatrics 2001;108(6). URL: http://www. pediatrics.org/cgi/content/full/108/6/e113; cystitis, eosinophilic, cyclosporin A.E osinophilic cystitis is a rare disorder of the urinary bladder, characterized by extensive local eosinophilic infiltration of all layers of the bladder wall, probably induced by a regulatory disorder of the immune system. Many possible causes have been postulated; nevertheless, the exact mechanism of the disease still needs to be clarified. This uncommon entity was first reported almost 40 years ago 1,2 and can be encountered in any age group, although it seems to be more common in adults. Eosinophilic cystitis has a broad spectrum of clinical and pathologic manifestations, ranging from mild inflammatory cystitis to severe chronic or recurrent relentless inflammation. [3][4][5][6][7][8] This disorder eventually can progress to a complete fibrosis of the urinary bladder with secondary involvement of the rest of the urinary tract, resulting in obstructive nephropathy with variable degrees of renal insufficiency. [3][4][5][6][7][8][9] We report a child who had severe progressive eosinophilic cystitis and did not respond to high-dose corticosteroid therapy and specific therapy for toxocariasis. Repeated bladder sonography suggested progressive reduction of the urinary bladder lumen with extensive fibrosis of the bladder wall. Longterm treatment with cyclosporin A resulted in clinical recovery with complete disappearance of the bladder eosinophilic infiltration. CASE REPORTA 4-year-old Jewish boy, who was born to a healthy mother of Turkish origin and a Moroccan father, had received a diagnosis of celiac disease. His 6-year-old sister was healthy. The patient was a term infant, appropriate for gestational age, and born after an uneventful pregnancy and delivery. Growth and development were normal. At age 1.5 years, he underwent a left orchidopexy for an undescended testis.He presented with a 2.5-month history of dysuria, urinary frequency and urgency, dribbling, and diurnal enuresis. Body temperature was normal. No abnormalities were detected in the physical examination. The laboratory results showed a white cell count of 12 000/ L with 32% neutrophils, 60% lymphocytes, 6% monocytes, and 2% eosinophils.Hemoglobin was 11.8 g/dL, and the red blood cell count was 4.54 ϫ 10 6 / L, with normal indices. Platelet count, erythrocyte sedimentation rat...

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