Eosinophilia Caused by Rifampin

Mungall, P. F.; Standing, V F

doi:10.1378/chest.74.3.321-c

Chest

1978

DOI: 10.1378/chest.74.3.321-c

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Eosinophilia Caused by Rifampin

P. F. Mungall¹,

V F Standing²

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1979

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Cited by 4 publications

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“…Para-aminosalicyclic acid and isoniazid are the two antituberculous drugs that have been reported to cause pulmonary eosinophilia [4][5][6]. Rifampicin has been reported to cause blood eosinophilia, but only in the presence of other drugs, such as isoniazid or streptomycin [7,8]. We report a case of ethambutol-induced blood eosinophilia and pulmonary infiltrates probably also eosinophilic in nature, which to the best of our knowledge has not previously been documented in the literature.…”

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confidence: 84%

Ethambutol-induced pulmonary infiltrates with eosinophilia and skin involvement

Wong¹,

Ww²,

Wong³

et al. 1995

Eur Respir J

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A 67 year old woman presented with miliary tuberculosis. She was treated with streptomycin, isoniazid, rifampicin, ethambutol and pyrazinamide. However, she developed rifampicin-induced thrombocytopenia after 6 weeks of treatment, and skin rash, blood eosinophilia and pulmonary infiltrates after 8 weeks of therapy. The latter was found to be ethambutol related. Additional evidence, including blood and sputum eosinophilia and the rapidity of its response to corticosteroid, suggested that the pulmonary infiltrates might also be eosinophilic in nature. To the best of our knowledge, this constitutes the first report of such adverse drug reaction, induced by ethambutol.

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mentioning

confidence: 84%

Ethambutol-induced pulmonary infiltrates with eosinophilia and skin involvement

Wong¹,

Ww²,

Wong³

et al. 1995

Eur Respir J

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A review of blood dyscrasias induced by the antituberculosis drugs

Holdiness¹

1987

Tubercle

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Eosinophilosia due to Rifampicin

Nigam¹,

Shukia²,

Dubey³

1979

Int J Dermatology

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Eosinophilia Caused by Rifampin

Cited by 4 publications

References 0 publications

Ethambutol-induced pulmonary infiltrates with eosinophilia and skin involvement

Ethambutol-induced pulmonary infiltrates with eosinophilia and skin involvement

A review of blood dyscrasias induced by the antituberculosis drugs

Eosinophilosia due to Rifampicin

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