Enzymmuster am Nephron, Quantitative histochemische Ergebnisse

Histochemical evaluation of mouse and rat kidneys with lectin‐horseradish peroxidase conjugates

“…This physiological diversity depends on a number of specialized cell types and on their chemical constituents, which have not been fully elucidated by histologic or biochemical methods. The histologic structure of the uriniferous tubules has been defined at the light microscopic level in a number of mammalian species (Moffat, 1975;Tisher, 1981) as has the histochemical distribution of several enzymes in the various morphologically defined portions of the tubule (for review see Wachstein and Bradshaw, 1968;Schmidt and Dubach, 1972;Jacobsen and Jqwgensen, 1973). More recently, immunostaining has served to localize various substances such as lysozyme (Glynn and Parkman, 1964;Klochars and Osserman, 1974;Mason and Taylor, 1975;Spicer et al, 1977), carbonic anhydrase (Spicer et al, 19791, renin (Menard et al, 1979;Taugner et al, 1979), and Tamm-Horsfall antigen (McKenzie and McQueen, 1969;Schenk et al, 1971) to discrete segments and cell types in the kidney tubule.…”