Enzymeless creatinine estimation using poly(3,4-ethylenedioxythiophene) -β-cyclodextrin

Kumar, T. Naresh; Ananthi, Arjunan; Mathiyarasu, J.; Joseph, James; Phani, K. L. N.; Yegnaraman, V.

doi:10.1016/j.jelechem.2011.08.001

Cited by 28 publications

(9 citation statements)

References 36 publications

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“…Again, it was shown that the PEDOT/β-CD outperformed the PEDOT in the sensitive and selective sensing of hyperoside and shikonin [124]. PEDOT/β-CD films have also been utilized in the electrochemical quantification of acetaminophen (paracetamol) [125], creatinine [126], sulfur oxoanions, and nitrite [127]. PEDOT and sulfated β-cyclodextrin (PEDOT/sβ-CD) films deposited onto gold were investigated for the simultaneous detection of ascorbic acid and catecholamines, giving good simultaneous analysis [128].…”

Section: Cyclodextrins Combined With Conducting Polymersmentioning

confidence: 99%

Cyclodextrins as Supramolecular Recognition Systems: Applications in the Fabrication of Electrochemical Sensors

et al. 2021

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Supramolecular chemistry, although focused mainly on noncovalent intermolecular and intramolecular interactions, which are considerably weaker than covalent interactions, can be employed to fabricate sensors with a remarkable affinity for a target analyte. In this review the development of cyclodextrin-based electrochemical sensors is described and discussed. Following a short introduction to the general properties of cyclodextrins and their ability to form inclusion complexes, the cyclodextrin-based sensors are introduced. This includes the combination of cyclodextrins with reduced graphene oxide, carbon nanotubes, conducting polymers, enzymes and aptamers, and electropolymerized cyclodextrin films. The applications of these materials as chiral recognition agents and biosensors and in the electrochemical detection of environmental contaminants, biomolecules and amino acids, drugs and flavonoids are reviewed and compared. Based on the papers reviewed, it is clear that cyclodextrins are promising molecular recognition agents in the creation of electrochemical sensors, chiral sensors, and biosensors. Moreover, they have been combined with a host of materials to enhance the detection of the target analytes. Nevertheless, challenges remain, including the development of more robust methods for the integration of cyclodextrins into the sensing unit.

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Section: Cyclodextrins Combined With Conducting Polymersmentioning

confidence: 99%

Cyclodextrins as Supramolecular Recognition Systems: Applications in the Fabrication of Electrochemical Sensors

et al. 2021

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“…Table 1 compares the effectiveness of several modified electrodes with the current Pd/Cu 2 O/PPy/GCE in the detection of creatinine. 49–57 Cu 2+ + creatinine + H 2 O → Cu + oxime creatinine + 2H + Pd 2+ + creatinine + H 2 O → Pd + oxime creatinine + 2H + …”

Section: Resultsmentioning

confidence: 99%

Non-enzymatic electrochemical detection of creatinine based on a glassy carbon electrode modified with a Pd/Cu₂O decorated polypyrrole (PPy) nanocomposite: an analytical approach

Nagarajan

Venkatesan²,

Raman

2023

Anal. Methods

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“…In this scenario, electrochemical sensors are presented as attractive analytical devices because they combine high sensitivity, simplicity of operation, and low cost [ 38 ]. In the literature, various types of enzymatic [ 39 ] and non-enzymatic [ 40 , 41 ] sensors are reported for the determination of CNN with different electrochemical techniques [ 42 , 43 , 44 ]. Although selective, enzyme biosensors have some limitations when compared to non-enzymatic electrodes.…”

Section: Introductionmentioning

confidence: 99%

Electrochemical Biosensor for SARS-CoV-2 cDNA Detection Using AuPs-Modified 3D-Printed Graphene Electrodes

et al. 2022

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A low-cost and disposable graphene polylactic (G-PLA) 3D-printed electrode modified with gold particles (AuPs) was explored to detect the cDNA of SARS-CoV-2 and creatinine, a potential biomarker for COVID-19. For that, a simple, non-enzymatic electrochemical sensor, based on a Au-modified G-PLA platform was applied. The AuPs deposited on the electrode were involved in a complexation reaction with creatinine, resulting in a decrease in the analytical response, and thus providing a fast and simple electroanalytical device. Physicochemical characterizations were performed by SEM, EIS, FTIR, and cyclic voltammetry. Square wave voltammetry was employed for the creatinine detection, and the sensor presented a linear response with a detection limit of 0.016 mmol L−1. Finally, a biosensor for the detection of SARS-CoV-2 was developed based on the immobilization of a capture sequence of the viral cDNA upon the Au-modified 3D-printed electrode. The concentration, immobilization time, and hybridization time were evaluated in presence of the DNA target, resulting in a biosensor with rapid and low-cost analysis, capable of sensing the cDNA of the virus with a good limit of detection (0.30 µmol L−1), and high sensitivity (0.583 µA µmol−1 L). Reproducible results were obtained (RSD = 1.14%, n = 3), attesting to the potentiality of 3D-printed platforms for the production of biosensors.

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Enzymeless creatinine estimation using poly(3,4-ethylenedioxythiophene) -β-cyclodextrin

Cited by 28 publications

References 36 publications

Cyclodextrins as Supramolecular Recognition Systems: Applications in the Fabrication of Electrochemical Sensors

Cyclodextrins as Supramolecular Recognition Systems: Applications in the Fabrication of Electrochemical Sensors

Non-enzymatic electrochemical detection of creatinine based on a glassy carbon electrode modified with a Pd/Cu₂O decorated polypyrrole (PPy) nanocomposite: an analytical approach

Electrochemical Biosensor for SARS-CoV-2 cDNA Detection Using AuPs-Modified 3D-Printed Graphene Electrodes

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Enzymeless creatinine estimation using poly(3,4-ethylenedioxythiophene) -β-cyclodextrin

Cited by 28 publications

References 36 publications

Cyclodextrins as Supramolecular Recognition Systems: Applications in the Fabrication of Electrochemical Sensors

Cyclodextrins as Supramolecular Recognition Systems: Applications in the Fabrication of Electrochemical Sensors

Non-enzymatic electrochemical detection of creatinine based on a glassy carbon electrode modified with a Pd/Cu2O decorated polypyrrole (PPy) nanocomposite: an analytical approach

Electrochemical Biosensor for SARS-CoV-2 cDNA Detection Using AuPs-Modified 3D-Printed Graphene Electrodes

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Non-enzymatic electrochemical detection of creatinine based on a glassy carbon electrode modified with a Pd/Cu₂O decorated polypyrrole (PPy) nanocomposite: an analytical approach