Enzyme responses and lipid peroxidation in gills and hepatopancreas of clam Mactra vereformis, following cadmium exposure

Wang, Xiaoyu; Yang, Hongsheng; Liu, Guangbin; Wang, Qing

doi:10.1007/s00343-011-0088-5

Cited by 17 publications

(7 citation statements)

References 44 publications

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“…Several studies have indicated that antioxidant enzyme activity may increase when bivalves are exposed to low heavy metal concentrations, or during shortterm exposure, but they may decrease or may even be inhibited at higher dosages, or after prolonged exposure. The results of our study support these previous findings (Géret et al, 2002a;Siraj Basha and Usha Rani, 2003;Wang et al, 2011) Many studies have indicated the role of SOD and CAT in relation to oxidant stress as well as in protecting cells against environmental pollutions (Monteiro et al, 2010;Umasuthan et al, 2012). In the current study, the hemocytes and gills showed different patterns of change in SOD activity.…”

Section: Discussionsupporting

confidence: 91%

“…In this study, MDA gradually accumulated in hemocytes of V. philippinarum exposed to mercury, and MDA content increased compared to the control. Similar results were found in the gills of the bivalve M. vereformis (Wang et al, 2011) and R. decussatus (Géret et al, 2002b). ROS in cells was not eliminated, causing oxidative stress, LPO, and eventually, MDA accumulation.…”

Section: Discussionsupporting

confidence: 77%

“…ACP activity in the gills of Mactra vereformis exposed to Cd was not activated until Day 3 and Day 5 (Wang et al, 2011). ALP is sensitive to metals, and the effects of metals on ALP have been reported in the clam Scrobicularia plana (Mazorra et al, 2002) and Mactra vereformis (Wang et al, 2011). In the current study, Hg exposure affected ALP activity in the hemocytes of M. Vereformis, however, a significant impact on gill ALP activity of M. Vereformis was seen only in the 10 µg/L Hg treatment group.…”

Section: Discussionmentioning

confidence: 97%

“…Hyperactivity of gill acid phosphatase in mussel Lamellidens corrianus (Lea) occurred at the time of mercury stress however when it dissipated, levels of enzyme activity returned to normal (Rajalakshmi and Mohandas, 2008). ACP activity in the gills of Mactra vereformis exposed to Cd was not activated until Day 3 and Day 5 (Wang et al, 2011). ALP is sensitive to metals, and the effects of metals on ALP have been reported in the clam Scrobicularia plana (Mazorra et al, 2002) and Mactra vereformis (Wang et al, 2011).…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Identification of Relevant Biomarkers in Mercury Exposed Clam Venerupis philippinarum.

Zhang¹,

Li²,

Jin³

et al. 2016

Israeli Journal of Aquaculture - Bamidgeh

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As from January 2010 The Israeli Journal of Aquaculture-Bamidgeh (IJA) will be published exclusively as an on-line Open Access (OA) quarterly accessible by all AquacultureHub (http://www.aquaculturehub.org) members and registered individuals and institutions. Please visit our website (http://siamb.org.il) for free registration form, further information and instructions. This transformation from a subscription printed version to an on-line OA journal, aims at supporting the concept that scientific peer-reviewed publications should be made available to all, including those with limited resources. The OA IJA does not enforce author or subscription fees and will endeavor to obtain alternative sources of income to support this policy for as long as possible.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 77%

Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Identification of Relevant Biomarkers in Mercury Exposed Clam Venerupis philippinarum.

Zhang¹,

Li²,

Jin³

et al. 2016

Israeli Journal of Aquaculture - Bamidgeh

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“…In fact, some studies have demonstrated that early-life stages are more sensitive than adults and show an early response to the exposure to environmental pollutants. Other studies showed that the activity of antioxidant enzymes can increase when the organism is exposed to low concentrations of chemical or during short-term exposures, but it can decrease or be inhibited at high concentration or after prolonged exposure (Valavanidis et al, 2006;Wang et al, 2011). Lastly, the induction of GST found after the exposure to both the BE concentrations suggests the involvement of phase II detoxification enzymes in the metabolism of BE in D. magna.…”

Section: Discussionmentioning

confidence: 94%

Benzoylecgonine exposure induced oxidative stress and altered swimming behavior and reproduction in Daphnia magna

Parolini

Felice

Ferrario

et al. 2018

Environmental Pollution

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Several monitoring studies have shown that benzoylecgonine (BE) is the main illicit drug residue commonly measured in the aquatic system worldwide. Few studies have investigated the potential toxicity of this molecule towards invertebrate and vertebrate aquatic non-target organisms focusing on effects at low levels of the biological organization, but no one has assessed the consequences at higher ones. Thus, the present study was aimed at investigating the toxicity of a 48-h exposure to two concentrations of BE, similar to those found in aquatic ecosystems (0.5 μg/L and 1.0 μg/L), on the cladoceran Daphnia magna at different levels of the ecological hierarchy. We relied on a multi-level approach focusing on the effects at biochemical/biomolecular (biomarkers), individual (swimming activity) and population (reproduction) levels. We measured the amount of reactive oxygen species and of the activity of antioxidant (SOD, CAT, and GPx) and detoxifying (GST) enzymes to assess if BE exposure can alter the oxidative status of D. magna specimens, while the lipid peroxidation (TBARS) was measured as a marker of oxidative damage. Moreover, we also measured the acetylcholinesterase (AChE) activity because it is strictly related to behavioral changes in aquatic organisms. Changes in swimming behavior were investigated by a video tracking analysis, while the consequences on reproduction were assessed by a chronic toxicity test. Our results showed that BE concentrations similar to those found in aquatic ecosystems induced oxidative stress and inhibited AChE activity, affecting swimming behavior and the reproduction of Daphnia magna individuals.

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Tissue-Specific Antioxidative Responses and Cadmium Accumulation in Silurus meridionalis Under Chronic Waterborne Cadmium Exposure

Yan

Xie

2018

Bull Environ Contam Toxicol

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In this study, the oxidative damage, antioxidative responses and cadmium (Cd) accumulation in juvenile Silurus meridionalis were studied, after S. meridionalis were exposed to 0 (control), 62.5, 125, 250 and 500 µg Cd/L for 56 days. Cd accumulation, malondialdehyde, superoxide dismutase (SOD), catalase, glutathione (GSH) and total antioxidant capacity (T-AOC) were determined in gill, liver, kidney and intestine tissues. The results showed that the Cd accumulation in S. meridionalis was dose-dependent and tissue-specific, with the highest Cd content in the kidney, followed by the liver, gill, and intestine. Waterborne Cd stress in S. meridionalis was expressed as tissue-specific oxidative damage and antioxidant responses in gill, liver, kidney and intestine tissues. Waterborne Cd exposure induced the most significant oxidative damage in the gill, followed by the liver and kidney, while the intestine showed no sensitivity to waterborne Cd exposure. The antioxidants, such as SOD in the liver, kidney and intestine, as well as T-AOC and GSH in the gill, liver and kidney, were sensitive to waterborne Cd exposure.

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Enzyme responses and lipid peroxidation in gills and hepatopancreas of clam Mactra vereformis, following cadmium exposure

Cited by 17 publications

References 44 publications

Identification of Relevant Biomarkers in Mercury Exposed Clam Venerupis philippinarum.

Identification of Relevant Biomarkers in Mercury Exposed Clam Venerupis philippinarum.

Benzoylecgonine exposure induced oxidative stress and altered swimming behavior and reproduction in Daphnia magna

Tissue-Specific Antioxidative Responses and Cadmium Accumulation in Silurus meridionalis Under Chronic Waterborne Cadmium Exposure

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