Enzymatic Biofuel Cells

Beilke, Michael C.; Klotzbach, Tamara L.; Treu, Becky L.; Sokic-Lazic, Daria; Wildrick, Janice; Amend, Elisabeth R.; Gebhart, Lindsay M.; Arechederra, Robert L.; Germain, Marguerite N.; Moehlenbrock, Michael J.; Sudhanshu,

doi:10.1016/b978-0-12-374713-6.00005-6

Cited by 9 publications

(6 citation statements)

References 111 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Applications in power implantable and portable biomedical devices such as miniaturized sensors, transmitters and artificial organs are of particular interest. Although there has been significant research dedicated to the design and development of EBFCs, [1][2][3][4][5][6] progress towards a fully operational EBFC has been slow and requires significant improvement before they can compete with conventional fuel cells. Before the full potential of EBFCs can be realized, effort must be made to enhance the characteristics of individual bioelectrodes with respect to enzyme function and stability and electrode materials that improve electron transfer and power output and to ensure long-term operation under real environmental conditions.…”

Section: Introductionmentioning

confidence: 99%

Graphene based enzymatic bioelectrodes and biofuel cells

et al. 2015

View full text Add to dashboard Cite

The excellent electrical conductivity and ease of functionalization make graphene a promising material for use in enzymatic bioelectrodes and biofuel cells. Enzyme based biofuel cells have attracted substantial interest due to their potential to harvest energy from organic materials. This review provides an overview of the functional properties and applications of graphene in the construction of biofuel cells as alternative power sources. The review covers the current state-of-the-art research in graphene based nanomaterials (physicochemical properties and surface functionalities), the role of these parameters in enhancing electron transfer, the stability and activity of immobilized enzymes, and how enhanced power density can be achieved. Specific examples of enzyme immobilization methods, enzyme loading, stability and function on graphene, functionalized graphene and graphene based nanocomposite materials are discussed along with their advantages and limitations. Finally, a critical evaluation of the performance of graphene based enzymatic biofuel cells, the current status, challenges and future research needs are provided.

show abstract

Section: Introductionmentioning

confidence: 99%

Graphene based enzymatic bioelectrodes and biofuel cells

et al. 2015

View full text Add to dashboard Cite

show abstract

“…Biofuel cells operate based on this principle: the target load is connected to an anode and a cathode and the biomolecular fuel source is oxidized at the anode, which drives electron transfer; oxygen reduction occurs at the cathode. [349][350][351][352] Glucose is a common fuel for these biofuel cells, since it is relatively abundant and continuously replenished in the body. The oxidation/reduction reaction of glucose and oxygen provides a theoretical cell voltage of 1.24 V for complete oxidation and 1.18 V for oxidation to gluconic acid.…”

Section: Chemical Energy Harvesting Methodsmentioning

confidence: 99%

Powering Implantable and Ingestible Electronics

Yang

Sencadas

You

et al. 2021

Adv Funct Materials

View full text Add to dashboard Cite

Implantable and ingestible biomedical electronic devices can be useful tools for detecting physiological and pathophysiological signals, and providing treatments that cannot be done externally. However, one major challenge in the development of these devices is the limited lifetime of their power sources. The state-of-the-art of powering technologies for implantable and ingestible electronics is reviewed here. The structure and power requirements of implantable and ingestible biomedical electronics are described to guide the development of powering technologies. These powering technologies include novel batteries that can be used as both power sources and for energy storage, devices that can harvest energy from the human body, and devices that can receive and operate with energy transferred from exogenous sources. Furthermore, potential sources of mechanical, chemical, and electromagnetic energy present around common target locations of implantable and ingestible electronics are thoroughly analyzed; energy harvesting and transfer methods befitting each energy source are also discussed. Developing power sources that are safe, compact, and have high volumetric energy densities is essential for realizing long-term in-body biomedical electronics and for enabling a new era of personalized healthcare.

show abstract

“…Over the last decade, these techniques have been combined and utilized for producing stable bioelectrodes. Today, problems with the instability of the mediator or the cofactor is frequently more common than problems with stability of the enzymes (Beilke et al, 2009). A final recent approach to enzyme stabilization is to utilize enzymes from thermophillic microorganisms (Beneyton et al, 2011;Campbell et al, 2012;Lojou, 2011), because enzymes that are stable at high temperatures typically have higher stability at room temperature than the non-thermophillic versions.…”

Section: Immobilization and Stabilization Of Enzymes At Electrode Surmentioning

confidence: 99%