Enzymaktivitäten im Serum von Kaninchen und Ratten — Referenzwerte und Tagesschwankungen. Serumenzyme und ihre Beeinflussung, I. Mitteilung

Dabew, D.; Mahlberg, F. A.; Struck, H

doi:10.1515/cclm.1976.14.1-12.561

Cited by 5 publications

(7 citation statements)

References 6 publications

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“…The values of AP activity found in this study fully correspond to those quoted as physiological for rabbits by Grötsch and Hajdu (1979), Lindena and Trautschold (1986), and Hewit et al (1989). However, the values found by us are higher than those reported by Dabew et al (1976) and Yu et al (1979), and lower than those published by Liker et al (1998).…”

Section: Discussioncontrasting

confidence: 81%

“…The serum LDH activity found in all groups of rabbits included in this experiment was higher than the values reported by Friedel and Mattenheimer (1970), Schievelbein et al (1970), Dabew et al (1976), Yu et al (1979), Lindena and Trautschold (1986) and Hewit et al (1989), they were equal to values published by Grötsch and Hajdu (1971), and lower than those reported by Liker et al (1998). That high level of serum LDH activity found in all groups of rabbits in this experiment was probably the result of a mild haemolysis that occurred during the taking of blood samples.…”

Section: Discussioncontrasting

confidence: 76%

“…They are higher than the values reported by Friedel and Mattenheimer (1970), Schievelbein et al (1970), Grötsch and Hajdu (1971), Dabew et al (1976), Lindena and Traut-schold (1986) and Liker et al (1998), but lower than those found by Lepitzki and Woolf (1991). The slightly higher AST and ALT values of rabbits included in this experiment were due to the slight haemolysis that occurred during the taking of blood samples, rather than to the nutritive influence of dehydrated olive cake pulp added to the feed.…”

Section: Discussioncontrasting

confidence: 57%

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Effect of Feeding Olive by-Products on Certain Blood Parameters and Serum Enzyme Activities of Fattening Rabbits

Rupić

Božikov

Mužic

et al. 1999

Acta Veterinaria Hungarica

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The effect of feeding different levels (10 and 20%) of dehydrated olive cake pulp on certain blood parameters and on the catalytic activity of serum enzymes was studied in fattening rabbits. A total of 60 rabbits were divided into a control group (C) and two experimental groups (E , E ), each comprising 10 males and 10 females.Rabbits of Group C received no dehydrated olive cake pulp in their diet, while rabbits of Group E and Group E were fed 10% and 20% dehydrated olive cake pulp, respectively. After Day 56 of the experiment, blood samples were obtained by cardiac puncture and certain blood parameters as well as the catalytic activity of serum enzymes were determined. Following the experimental feeding period no significant differences were found between Group C and Groups E and E in red blood cell (RBC) and white blood cell (WBC) count, haemoglobin concentration and haematocrit value. Similarly, after 56 days of experimental fattening no significant differences were found between the control group and the experimental groups in the catalytic activity of the serum enzymes alkaline phosphatase (AP), aspartate aminotransferase (AST), gamma-glutamyltransferase (GGT), and lactate dehydrogenase (LDH). However, Group E rabbits manifested a significantly higher alanine aminotransferase (ALT) activity in the serum than did rabbits of Group E . The results indicate that the inclusion of dehydrated olive cake pulp in the diet at the rate of 10% or 20% caused no changes in the investigated blood parameters and serum enzyme activities of fattening rabbits.

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Section: Discussioncontrasting

confidence: 81%

Section: Discussioncontrasting

confidence: 76%

Section: Discussioncontrasting

confidence: 57%

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Effect of Feeding Olive by-Products on Certain Blood Parameters and Serum Enzyme Activities of Fattening Rabbits

Rupić

Božikov

Mužic

et al. 1999

Acta Veterinaria Hungarica

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“…On selected enzymes of diagnostic importance Dabew et al (58) found diurnal Variation in neither rabbit nor rat plasma, whereas Statland et al (71) in man demonstrated a significant Variation with time for acid phosphatase only.…”

Section: Diurnal Variation; Age and Sexmentioning

confidence: 98%

“…Blood from the tail veins of rats also seems unsuitable because the "normal" values are much to high. This technique also yields only small volumes of blood (58). Enzymes of mainly visceral origin like alanine aminotransferase, cholinesterase, alkaline phosphatase etc., show markedly lower catalytic activities in muscle tissue (up to 3 l O 2 fold higher compared to plasma) than the "critical" enzymes.…”

Section: Blood Drawing Techniquesmentioning

confidence: 99%

Catalytic Enzyme Activity Concentration in Plasma of Man, Sheep, Dog, Cat, Rabbit, Guinea Pig, Rat and Mouse. Approach to a Quantitative Diagnostic Enzymology. I. Communication

Lindena¹,

Trautschold²

1986

Clinical Chemistry and Laboratory Medicine

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Summary:For the most convenient laboratory animals in experimental medicine such äs the sheep, dog, cat, rabbit, guinea pig, rat and mouse, the catalytic concentrations of seventeen enzymes and the protein and albumin concentrations in plasma were determined. The corresponding data for man were taken from the literature. The experimental conditions were selected so äs to minimize the influence on catalytic activity, variance and statistical distribution pattern of such factors äs handling procedures, the choice of blood drawing technique, the choice of anaesthetic agent for distinct species and the preparation procedure of plasma from the blood specimen. Because these considerations have been largely neglected to date in experimental enzymology, normal values for most enzymes require revision and were in some instances established for the first time in certain species. Our use of assay conditions, which were identical for all animal species, satisfies current requirements in clinical chemistry with respect to standardization and optimization of enzyme catalytic activity concentration measurement, and allowed comparison of these enzymes. The catalytic activities established this way will be the basis for a later comparative study of their kinetics of adjustment in plasma. Katalytische Konzentration von Enzymen im Plasma von Mensch und Versuchstieren Versuch der Begründung einer quantitativen Diagnostisch-!· Enzymologie, I. Zusammenfassung: Bei den in der experimentellen

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Biological, Analytical and Experimental Components of Variance in a Long-Term Study of Plasma Constituents in Rat

Lindena¹,

Büttner²,

Trautschold³

1984

Clinical Chemistry and Laboratory Medicine

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Summary: Statistical analysis of variance was applied to data from determinations of 14 plasma constituents in 25 rats in order to evaluate the analytical* experimental and biological (inter-and intraindividual) component of variance. Blood was taken seven times in intervals of 8-10 days, the last one by catheter technique and the other by heart puncture. The analytical portion of variance was determined by the concurrent analysis of a pool plasma Standard. The experimental component of variance was evaluated by the comparison of the Variation of the catheter values with that of the pooled data froin heart puncture. The coefficient of Variation for the latter may be grouped into three categories: less than 10% for protein, Na + , K + , Ca 2+ ; 10-20% for urea, phosphate and the enzymes äs alanine aminotransferase, choline esterase, alkaline phosphatase and leucine arylamidase and 20^-65% for the other enzymes lactate dehydrogenase, malate dehydrogenase, aspartate aminotransferase and creatine kinase. The results from the samples taken by catheter technique generälly revealed the lower values for the mean äs well äs for the variance. It became evident that the procedure of heart puncture is afflicted with the most aggravating interference factors, thus accounting for most of the experimental component of variance. The observed differences between the single blood drawings, the nonGaussian distribution for several constituents, and the interactions between the components of variance do not always fit for the Statistical concept of additivity of the single components. Therefore the result for the partition öf the variance in single components may be more or less approximative in the strict sense of Statistical values, but it provides a practical guide for clinical chemical research with small laboratory animals. Biologische, analytische und experimentelle Varianzkomponenten von Plasmamerkmalen in einer Langzeitstu

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Enzymaktivitäten im Serum von Kaninchen und Ratten — Referenzwerte und Tagesschwankungen. Serumenzyme und ihre Beeinflussung, I. Mitteilung

Cited by 5 publications

References 6 publications

Effect of Feeding Olive by-Products on Certain Blood Parameters and Serum Enzyme Activities of Fattening Rabbits

Effect of Feeding Olive by-Products on Certain Blood Parameters and Serum Enzyme Activities of Fattening Rabbits

Catalytic Enzyme Activity Concentration in Plasma of Man, Sheep, Dog, Cat, Rabbit, Guinea Pig, Rat and Mouse. Approach to a Quantitative Diagnostic Enzymology. I. Communication

Biological, Analytical and Experimental Components of Variance in a Long-Term Study of Plasma Constituents in Rat

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