“…22 In this work, in silico study for Lipinski parameters was carried out using the OSIRIS Property Explorer software, 23 MolSoft Molecules in Silico 24 and ALOGPS 2.1 programs 25,26 in order to verify the theoretical oral bioavailability potential of mesoionic derivatives 7a-j. TPSA, %ABS, log S, drug likeness and drug score, representing the combined physicochemical, pharmacokinetic and pharmacodynamic effect, as well as lipophilicity, were also included.…”