Environmental triggers of acute myocardial infarction: does air pollution matter?

Coenen, Sarah; Colpaert, Charlotte; Bilcke, Joke; Beutels, Philippe; Damme, Pierre Van; Legrand, Victor; Vrints, C.; Claeys, Marc J.

doi:10.1093/eurheartj/eht308.1769

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“…Previous evidence shows that cold weather increases the risk of AMI 4 , with studies conducted in the different climate regions such as central and western Europe, and Asia 13 , 14 , 16 , 17 . Our findings are in agreement with this evidence and provide additional insights of a similar association in Lithuania, where some previous evidence exists on associations between weather and health 18 – 20 .…”

Section: Discussionmentioning

confidence: 99%

Association between winter cold spells and acute myocardial infarction in Lithuania 2000–2015

Vaičiulis

Jaakkola

Radišauskas

et al. 2021

Sci Rep

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Acute myocardial infarction (AMI) is a major public health problem. Cold winter weather increases the risk of AMI, but factors influencing susceptibility are poorly known. We conducted an individual-level case-crossover study of the associations between winter cold spells and the risk of AMI, with special focus on survival at 28 days and effect modification by age and sex. All 16,071 adult cases of AMI among the residents of the city of Kaunas in Lithuania in 2000–2015 were included in the study. Cold weather was statistically defined using the 5th percentile of frequency distribution of daily mean temperatures over the winter months. According to conditional logistic regression controlling for time-varying and time-invariant confounders, each additional cold spell day during the week preceding AMI increased the risk of AMI by 5% (95% CI 1–9%). For nonfatal and fatal cases, the risk increase per each additional cold spell day was 5% (95% CI 1–9%) and 6% (95% CI − 2–13%), respectively. The effect estimate was greater for men (OR 1.07, 95% CI 1.02–1.12) than for women (OR 1.02, 95% CI 0.97–1.08), but there was no evidence of effect modification by age. Evidence on factors increasing susceptibility is critical for targeted cold weather planning.

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