Environmental factors contributed to circannual rhythm of semen quality

Mao, Hong; Feng, Lei; Yang, Wan-Xi

doi:10.1080/07420528.2017.1280046

Cited by 22 publications

(17 citation statements)

References 45 publications

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“…Normal sperm morphology was evaluated in samples stained using the Papanicolaou technique (Baso Diagnostics Inc., Zhuhai, China) and analyzed according to the WHO 2010 criteria. 20…”

Section: Semen Analysismentioning

confidence: 99%

<p>Association Between Sleep Quality and Semen Parameters and Reproductive Hormones: A Cross-Sectional Study in Zhejiang, China</p>

Du¹,

Yang²,

Chen³

et al. 2020

NSS

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Background: The effects of sleep duration on semen quality have been documented in many epidemiological studies. However, the association between sleep quality and semen parameters and reproductive hormones is still unclear. Patients Enrollment and Methods: We conducted a cross-sectional study among 970 outpatients from the Reproductive Medicine Center in Zhejiang, China between October 2017 and July 2019. All participants delivered a semen sample, underwent a physical examination, and answered a questionnaire to provide the following information: demographics, life habits, and sleep habits. Sleep quality was measured using the Pittsburgh Sleep Quality Index (PSQI). We first divided the patients into two groups according to sleep quality (good sleep: PQSI < 5 and poor sleep: PSQI ≥ 5). Then, we analyzed routine sperm parameters (semen volume, sperm total motility, progressive motility, sperm concentration, total sperm number, and normal sperm morphology) and reproductive hormones (folliclestimulating hormone, luteinizing hormone, estrogen, testosterone, and prolactin) of each group. Finally, we used multivariate linear regression analysis and Spearman correlation coefficients to examine the relationship between sleep quality (discrete variable or dichotomous variable) and sperm parameters, reproductive hormones. Results: A negative correlation was found between the general PSQI scores and several semen parameters: total motility (r= −0.187979, p< 0.001), progressive motility (r= −0.192902, p< 0.001), concentration (r= −0.167063, p< 0.001), total sperm number (r= −0.160008, p< 0.001), and normal sperm morphology (r= −0.124511, p< 0.001). However, there was no significant correlation between the semen volume, all reproductive hormones and the general PSQI scores. After adjusting for confounders, men with poor sleep had lower total motility (β= −9.287; 95% CI, −12.050, −6.523), progressive motility (β= −8.853; 95% CI, −11.526, −6.180), concentration (log scale, β= −0.131; 95% CI, −0.181, −0.082), total sperm number (log scale, β= −0.137; 95% CI, −0.189, −0.084), and normal sperm morphology (β= −1.195; 95% CI, −1.844, −0.547), but semen volume and all reproductive hormones were not markedly altered. Conclusion: Poor sleep quality might be related to impaired semen quality, but we found no evidence that poor sleep quality affects reproductive hormones.

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“…Normal sperm morphology was evaluated in samples stained using the Papanicolaou technique (Baso Diagnostics Inc., Zhuhai, China) and analyzed according to the WHO 2010 criteria. 20…”

Section: Semen Analysismentioning

confidence: 99%

<p>Association Between Sleep Quality and Semen Parameters and Reproductive Hormones: A Cross-Sectional Study in Zhejiang, China</p>

Du¹,

Yang²,

Chen³

et al. 2020

NSS

Self Cite

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“…The circumpolar populations are exposed by the unique complex of adverse environmental factors such as low air temperature, marked seasonality, and peculiar photoperiod with very low day-light hours in winter and elevated ones in summer. These adverse conditions, especially contrast photoperiod, can vastly affect male fertility since the spermatogenesis is known to be susceptible to environmental factors including a length of light day [50,51]. It was revealed that the circumpolar populations are characterized by elevated basal metabolic rate [52]; hyperactivity of the thyroid gland, increased fatty acid metabolism [53], with both functional and genetic factors contributing to metabolic adaptation to the northern conditions [52].…”

Section: Discussionmentioning

confidence: 99%

Ethnic Differences in Spermatozoa Morphological Defects Diversity Among Men From Eastern Siberia, Russia

Клещев

Осадчук

Шантанова

et al. 2020

Preprint

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Background.Sperm morphology defects are considered to indicate several spermiogenesis anomalies, resulting in decreased men fertility, causing not only poor sperm morphology but also increased DNA fragmentation, chromatin condensation defects, increased oxidative stress. Consequently, detailed assessment of sperm morphological abnormalities in additional to counting percentage of sperm with normal morphology may be useful for andrologists and reproductive biologists. However, a little attention is paid to studying a regional and especially ethnic variability in the incidence of the sperm morphology defects. The aim of this research was to estimate ethnic variability in percentages of the sperm morphology abnormalities in men from general population living in the Siberian region of the Russian Federation.Methods.Male volunteers of Buryat (n=195), Yakut (n=130), and Slavic (n=89) ethnicity from the general population from Ulan-Ude and Yakutsk at least 5 years were enrolled in the study. Percentages of sperm morphological defects (according to the classification provided by the WHO laboratory manual, 2010) are counted after staining native ejaculate smears by Diff-Quick kits. Results.Among sperm defect, amorphous (62.25±12.18%), elongated (10.61±8.62%), pyriform(8.61±9.17%), and vacuolated heads (10.31±6.77%), abnormal acrosome (20.43±12.67%), asymmetrical insertion neck (18.33±6,43%), thick midpiece (6.21±3,41%), bent head (5.94±4,02%) and coiled tail (10.8±6.79%) were most frequent. In comparison with Buryats, Slavs and Yakuts were characterized by the decreased proportion sperm with normal morphology, the increased proportion of pyriform, elongated heads, abnormal acrosome, asymmertical tail insertion, excessive residual cytoplasm and increased teratozoospermia index (TZI). It was shown that impared progressive sperm motility and concentration associated with decreased percentage of sperm with normal morphology and increased proportion most of sperm morphology defects and TZI. However, increasing TZI in men with oligoastenozoospermia compared to men with astenozoospermia was revealed for Buryats only, suggesting ethnic features in the relationships between sperm morphology and concentration.Conclusion.The present study showed significant coordinated ethnic variability in the percentages of several sperm morphological defects in men from the general population located in Eastern Siberia. Damaged spermiogenesis processes underlying sperm head elongation and tail formation is considered to be significant contributors to geographical and ethnic variability of sperm morphology in men from the studied populations.

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“…A study of 12,245 semen samples from 7068 males showed that semen quality (total sperm count, sperm motility or normal morphology) varied according to both circadian and circannual rhythms in humans (Xie et al 2018). Increased length of daylight positively correlated with progressive sperm motility as well (Mao et al 2017). Genetic epidemiological studies have also shown that circadian clock gene polymorphisms are linked to semen parameters and risk for infertility.…”

Section: The Role Of Circadian System In Male Reproductive Biologymentioning

confidence: 99%

“…Hodzic et al (2013) Patients with idiopathic infertility (n = 517) and fertile men (n = 444)Genetic variability in CLOCK associated with male infertilityMao et al (2017) Cases for routine semen analysis (n = 8168), morphology ( n = 5819) and anti-sperm antibodies analysis (n = 5544)Positive correlation between increased length of daylight and progressive sperm motilityXie et al (2018) 12,245 semen samples (n = 7068 men) Circadian and circannual variations on semen qualityNi et al (2019) Human semen samples (n = 10,752) Diurnal variations on sperm DNA fragmentation Chronobiology, reproduction and offspring healthR85Reproduction (2020) 160 R79-R94…”

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confidence: 99%

Chronodisruption: effects on reproduction, transgenerational health of offspring and epigenome

Satı

2020

Reproduction

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The circadian system regulates the daily temporal organization in behavior and physiology, including neuroendocrine rhythms and reproduction. Modern life, however, increasingly impacts this complex biological system. Due to limitations of working with human subjects exposed to shiftwork schedules, most chronoregulation research has used rodent models. Recent publications in these model systems have emphasized the negative effects of circadian rhythm disruption on both female and male reproductive systems and fertility. Additionally, there is growing concern about the long-term effects of circadian rhythm disruptions during pregnancy on human offspring and their descendants as circadian regulation during pregnancy can also alter epigenetic programing in offspring. However, to truly know if such concerns apply to humans will require retrospective and prospective human studies. Therefore, this review will highlight the latest available evidence regarding potential effects of chronodisruption on both female and male reproductive systems. Additionally, it presents a comprehensive summary of transgenerational and epigenetic effects on adult offspring that result from maternal chronodisruption.

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Environmental factors contributed to circannual rhythm of semen quality

Cited by 22 publications

References 45 publications

<p>Association Between Sleep Quality and Semen Parameters and Reproductive Hormones: A Cross-Sectional Study in Zhejiang, China</p>

<p>Association Between Sleep Quality and Semen Parameters and Reproductive Hormones: A Cross-Sectional Study in Zhejiang, China</p>

Ethnic Differences in Spermatozoa Morphological Defects Diversity Among Men From Eastern Siberia, Russia

Chronodisruption: effects on reproduction, transgenerational health of offspring and epigenome

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