Environmental exposure to metals and the risk of high blood pressure: a cross-sectional study from NHANES 2015–2016

Rahman, Humairat H; Niemann, Danielle; Munson-McGee, Stuart H.

doi:10.1007/s11356-021-15726-0

Cited by 23 publications

(4 citation statements)

References 28 publications

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“…Statistical significance was determined using a two-sided p < 0.05. To account for the complex sampling design of NHANES, the survey package and logistic regression models were used for all analyses [ 27 , 28 ]. The entire analysis was conducted using R version 4.1.1.…”

Section: Methodsmentioning

confidence: 99%

Investigating the relationship between muscle mass and nasal Methicillin-Resistant Staphylococcus aureus (MRSA) colonization: Analysis of the National Health and Nutrition Examination Survey (NHANES)

Chen,

Li,

Lin

et al. 2024

PLoS ONE

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Background Methicillin-resistant Staphylococcus aureus (MRSA) nasal colonization is associated with an increased risk of infection disease. Low muscle mass has been linked to higher levels of inflammatory markers and weakened immune response, which may impact the susceptibility to nasal MRSA colonization. The relationship between muscle function and immune response to pathogens may be bidirectional. This study investigates the association between muscle mass and nasal MRSA colonization in adults. Methods The present cross-sectional study utilized data from the National Health and Nutrition Examination Survey (NHANES) conducted between 2001 and 2004. Appendicular skeletal muscle mass (ASM) adjusted by body mass index (BMI) (ASM/BMI) was used to evaluate muscle mass. Multivariate logistic regression, adjusted for demographic and infection factors, was used to analyze the association between muscle mass and nasal colonization by MRSA. A subgroup analysis based on age and gender was performed to assess the impact of muscle mass on nasal MRSA colonization. Results Nasal MRSA colonization was more prevalent in females, those with smaller household sizes, lower income, lower ASM/BMI, those who had stayed in healthcare facilities in the past 12 months, and individuals with diabetes and smoking habits. After adjusting for confounding factors, a dose-dependent association was found between decreasing quartiles of ASM/BMI and the risk of nasal MRSA colonization (p < 0.05). Additionally, per 1 unit increase in ASM/BMI was related to a 64% lower risk of nasal MRSA colonization. Conclusions This study suggests a significant negative correlation between ASM/BMI and the risk of nasal MRSA colonization. However, more prospective studies are required to investigate the causal relationship between muscle mass and colonization.

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Section: Methodsmentioning

confidence: 99%

Investigating the relationship between muscle mass and nasal Methicillin-Resistant Staphylococcus aureus (MRSA) colonization: Analysis of the National Health and Nutrition Examination Survey (NHANES)

Chen,

Li,

Lin

et al. 2024

PLoS ONE

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“…The survey package and the logistics regression models were used to create the survey design object. [ 19 , 20 ] All analyses were performed using R (version 4.1.1).…”

Section: Methodsmentioning

confidence: 99%

The association between antibiotics and community-associated Staphylococcus aureus colonization in the United States population: Analysis of the National Health and Nutrition Examination Survey (NHANES)

Chen

Shi

et al. 2022

Medicine

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Staphylococcus aureus nasal colonization is a seriously opportunistic infection. However, there is a lack of research of relationship between antibiotics and S aureus colonization in the general population. Through a cross-sectional investigation, this study intends to establish the parameters related to S aureus nasal colonization, specifically the function antibiotics play in colonization. The key information from 2001 to 2004 was abstracted from National Health and Nutrition Examination Survey (NHANES), including information on general demographics, health care status, antibiotic prescription, diabetes, alcohol consumption, and tobacco smoke exposure. The participants colonized with methicillin-susceptible S aureus (MSSA), or methicillin-resistant S aureus (MRSA) were defined as the case group, and the control group was subjects without positive S aureus colonization. Univariate and multivariate logistic regression models were used to identify the variables associated with MSSA and MRSA colonization. The records of 18,607 individuals were included, involving 13,205 cases without S aureus colonization, 5195 cases with MSSA, and 207 cases with MRSA. In the multivariate logistic regression analysis, the risk of MSSA colonization was significantly reduced with fluoroquinolone use (75% risk reduction, P = .02), sulfonamide use (98% risk reduction, P < .01), tetracycline use (81% risk reduction, P < .01) and antibiotic combination therapy (risk reduction 76%, P < .01). Female, race and total household size were strongly associated with MSSA carriage. On the other hand, regarding MRSA colonization, fluoroquinolone use, long-term care, and former smoker were positively associated with MRSA colonization, while high income was negatively associated with MRSA colonization. More proper use of broad-spectrum antibiotics contributes to reducing MSSA colonization. Former smokers should also practice better personal hygiene to limit the possibility of MRSA colonization.

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“…For the present Opinion, the CONTAM Panel identified 87 additional studies from a literature search and from nine systematic reviews (Abhyankar et al., 2012; Bao et al., 2022; Chowdhury et al., 2018; Karachaliou et al., 2021; Moon et al., 2012, 2017; Tsuji et al., 2014; Xu, Mondal, & Polya, 2020; Zhao et al., 2021). Out of these, 53 studies (Afridi et al, 2011; Ameer et al, 2015; Castiello et al, 2020; Cheng et al, 2021; Dastgiri et al, 2010; Desai et al, 2021; Dong et al, 2022; Gong & O'Bryant, 2012; Guha Mazumder et al, 2012; Gunduz et al, 2015; Guo et al, 2007; Hall et al, 2017; Jovanović et al, 2012; Liao et al, 2012; Lin, Hsu, et al, 2018; Lisabeth et al, 2010; Liu et al, 2022; McLeod et al, 2018; Meliker et al, 2007; Merrill et al, 2017; Nong et al, 2016; Nunes et al, 2022; Pichler et al, 2019; Qu et al, 2022; Rahman et al, 1999, 2014; Rahman, Niemann, & Munson‐McGee, 2022c; Shiue, 2014; Sohel et al, 2009; Soria et al, 2021; Stea et al, 2016; Tang et al, 2022; Wang et al, 2002; Wang et al, 2011; Wang, Hao, et al, 2020; Wang, Karvonen‐Gutierrez, et al, 2021; Wang, Wu, et al, 2007; Wei, Yu, et al, 2017; Wen et al, 2019; Wu et al, 2010; Xu et al, 2021; Xu, Liu, et al, 2022; Xu, Polya, et al, 2020; Yao et al, 2021; Yen et al, 2022; Yildiz et al, 2008; Y...…”

Section: Assessmentmentioning

confidence: 99%

Update of the risk assessment of inorganic arsenic in food

Schrenk,

Bignami,

Bodin

et al. 2024

EFS2

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The European Commission asked EFSA to update its 2009 risk assessment on arsenic in food carrying out a hazard assessment of inorganic arsenic (iAs) and using the revised exposure assessment issued by EFSA in 2021. Epidemiological studies show that the chronic intake of iAs via diet and/or drinking water is associated with increased risk of several adverse outcomes including cancers of the skin, bladder and lung. The CONTAM Panel used the benchmark dose lower confidence limit based on a benchmark response (BMR) of 5% (relative increase of the background incidence after adjustment for confounders, BMDL05) of 0.06 μg iAs/kg bw per day obtained from a study on skin cancer as a Reference Point (RP). Inorganic As is a genotoxic carcinogen with additional epigenetic effects and the CONTAM Panel applied a margin of exposure (MOE) approach for the risk characterisation. In adults, the MOEs are low (range between 2 and 0.4 for mean consumers and between 0.9 and 0.2 at the 95th percentile exposure, respectively) and as such raise a health concern despite the uncertainties.

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Environmental exposure to metals and the risk of high blood pressure: a cross-sectional study from NHANES 2015–2016

Cited by 23 publications

References 28 publications

Investigating the relationship between muscle mass and nasal Methicillin-Resistant Staphylococcus aureus (MRSA) colonization: Analysis of the National Health and Nutrition Examination Survey (NHANES)

Investigating the relationship between muscle mass and nasal Methicillin-Resistant Staphylococcus aureus (MRSA) colonization: Analysis of the National Health and Nutrition Examination Survey (NHANES)

The association between antibiotics and community-associated Staphylococcus aureus colonization in the United States population: Analysis of the National Health and Nutrition Examination Survey (NHANES)

Update of the risk assessment of inorganic arsenic in food

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