Environmental Enrichment Rescues Oxidative Stress and Behavioral Impairments Induced by Maternal Care Deprivation: Sex- and Developmental-Dependent Differences

Réus, Gislaine Z.; Abitante, Morgana S; Manosso, Luana M.; Moura, Airam B. de; Borba, Laura A.; Botelho, Maria Eduarda M.; Darabas, Ana Caroline; Demo, Júlia P.; Behenck, João Paulo; Arent, Camila O.; Garbossa, Leandro; Joaquim, Larissa; Cardoso, Taiane Azevedo; Petronilho, Fabrícia; Quevedo, João

doi:10.1007/s12035-021-02588-3

Cited by 6 publications

(2 citation statements)

References 79 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Bonnet macaques cluster in larger groups and their infants' separation reaction, rather than strong distress, is to interact with other adults, generating solicitous behaviours including adoption. Rodents show that early adversity leads later in life to anxiety-like behaviours and increased stress responsiveness (Hegde & Mitra, 2020) in a sex-and age-dependent manner (Réus et al, 2021;Zanta, Suchecki, & Girardi, 2021) that can be enhanced by acute stress (Zanta et al, 2021) and ameliorated by an enriched environment (Réus et al, 2021).…”

Section: Genes Environment and Personalitymentioning

confidence: 99%

Non-human contributions to personality neuroscience – from fish through primates. An introduction to the special issue

Lages

McNaughton²

2022

Personality Neuroscience

View full text Add to dashboard Cite

The most fundamental emotional systems that show trait control are evolutionarily old and extensively conserved. Psychology in general has benefited from non-human neuroscience and from the analytical simplicity of behaviour in those with simpler nervous systems. It has been argued that integration between personality, psychopathology, and neuroscience is particularly promising if we are to understand the neurobiology of human experience. Here, we provide some general arguments for a non-human approach being at least as productive in relation to personality, psychopathology, and their interface. Some early personality theories were directly linked to psychopathology (e.g., Eysenck, Panksepp, and Cloninger). They shared a common interest in brain systems that naturally led to the use of non-human data; behavioural, neural, and pharmacological. In Eysenck’s case, this also led to the selective breeding, at the Maudsley Institute, of emotionally reactive and non-reactive strains of rat as models of trait neuroticism or trait emotionality. Dimensional personality research and categorical approaches to clinical disorder then drifted apart from each other, from neuropsychology, and from non-human data. Recently, the conceptualizations of both healthy personality and psychopathology have moved towards a common hierarchical trait perspective. Indeed, the proposed two sets of trait dimensions appear similar and may even be eventually the same. We provide, here, an introduction to this special issue of Personality Neuroscience, where the authors provide overviews of detailed areas where non-human data inform human personality and its psychopathology or provide explicit models for translation to human neuroscience. Once all the papers in the issue have appeared, we will also provide a concluding summary of them.

show abstract

Section: Genes Environment and Personalitymentioning

confidence: 99%

Non-human contributions to personality neuroscience – from fish through primates. An introduction to the special issue

Lages

McNaughton²

2022

Personality Neuroscience

View full text Add to dashboard Cite

show abstract

“…A different approach has been developed using animal models of depression, which mimic both the etiology of depression and the human-like depression symptoms ( McKinney and Bunney, 1969 ). Indeed, depression-like symptoms resembling that seen in the human response to chronic stress can be induced in rats and mice following chronic isolation, pain, learned helplessness, social defeat, minor stressors, maternal deprivation, striatal intracerebral hemorrhage, forced swimming, restraint, olfactory bulb removal, and tail suspension ( Kelly et al, 1997 ; Veena et al, 2009 ; Richter et al, 2013 ; Gong et al, 2018 ; Seong et al, 2018 ; Hao et al, 2019 ; Wang et al, 2019 ; Sparling et al, 2020 ; Borba et al, 2021 ; Cordner et al, 2021 ; Ramírez-Rodríguez et al, 2021 ; Réus et al, 2021 ; Taheri Zadeh et al, 2021 ; Kimura et al, 2022 ). Moreover, the therapies used to treat humans with depression are also effective in reversing induced depression in lab animals, including antidepressants, electroconvulsive seizure therapy, and deep brain stimulation ( Jeannotte et al, 2009 ; Falowski et al, 2011 ; Tizabi et al, 2012 ; Belujon and Grace, 2014 ; Song and Kim, 2021 ).…”

Section: Introductionmentioning

confidence: 99%

Olfactory loss is a predisposing factor for depression, while olfactory enrichment is an effective treatment for depression

Leon

Woo

2022

Front. Neurosci.

View full text Add to dashboard Cite

The loss of olfactory stimulation correlates well with at least 68 widely differing neurological disorders, including depression, and we raise the possibility that this relationship may be causal. That is, it seems possible that olfactory loss makes the brain vulnerable to expressing the symptoms of these neurological disorders, while daily olfactory enrichment may decrease the risk of expressing these symptoms. This situation resembles the cognitive reserve that is thought to protect people with Alzheimer’s neuropathology from expressing the functional deficit in memory through the cumulative effect of intellectual stimulation. These relationships also resemble the functional response of animal models of human neurological disorders to environmental enrichment, wherein the animals continue to have the induced neuropathology, but do not express the symptoms as they do in a standard environment with restricted sensorimotor stimulation.

show abstract

Improved Spatial Memory And Neuroinflammatory Profile Changes in Aged Rats Submitted to Photobiomodulation Therapy

et al. 2021

View full text Add to dashboard Cite

Environmental Enrichment Rescues Oxidative Stress and Behavioral Impairments Induced by Maternal Care Deprivation: Sex- and Developmental-Dependent Differences

Cited by 6 publications

References 79 publications

Non-human contributions to personality neuroscience – from fish through primates. An introduction to the special issue

Non-human contributions to personality neuroscience – from fish through primates. An introduction to the special issue

Olfactory loss is a predisposing factor for depression, while olfactory enrichment is an effective treatment for depression

Improved Spatial Memory And Neuroinflammatory Profile Changes in Aged Rats Submitted to Photobiomodulation Therapy

Contact Info

Product

Resources

About