2014
DOI: 10.3390/e16126384
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Entropy Analysis of RR and QT Interval Variability during Orthostatic and Mental Stress in Healthy Subjects

Abstract: Autonomic activity affects beat-to-beat variability of heart rate and QT interval. The aim of this study was to explore whether entropy measures are suitable to detect changes in neural outflow to the heart elicited by two different stress paradigms. We recorded short-term ECG in 11 normal subjects during an experimental protocol that involved head-up tilt and mental arithmetic stress and computed sample entropy, cross-sample entropy and causal interactions based on conditional entropy from RR and QT interval … Show more

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Cited by 21 publications
(16 citation statements)
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“…In addition, in both groups we were able to observe a decrease in SampEn values in Phase 2 and Phase 4 if we compared with pre-exercise and post-exercise stages, being a higher difference in the asymptomatic group. In other articles, similar results were shown, where the head-up tilt test resulted in a significant reduction in SampEn of R-R interval, these measures of entropy are suitable to detect changes in neural outflow to the heart and decoupling of repolarization variability from heart rate variability elicited by orthostatic stress [15]. On the other hand, the symptomatic OI group showed higher SampEn values in all stages, but these differences between both groups did not reach statistical significance.…”
Section: Resultssupporting
confidence: 67%
“…In addition, in both groups we were able to observe a decrease in SampEn values in Phase 2 and Phase 4 if we compared with pre-exercise and post-exercise stages, being a higher difference in the asymptomatic group. In other articles, similar results were shown, where the head-up tilt test resulted in a significant reduction in SampEn of R-R interval, these measures of entropy are suitable to detect changes in neural outflow to the heart and decoupling of repolarization variability from heart rate variability elicited by orthostatic stress [15]. On the other hand, the symptomatic OI group showed higher SampEn values in all stages, but these differences between both groups did not reach statistical significance.…”
Section: Resultssupporting
confidence: 67%
“…The result of their study showed the increment of Kolmogorov–Sinai entropy in reflexological stimulation compare to relaxed sitting, which indicates that the ECG signal becomes more random with reflexology. Baumert et al 27. explored the influence of head-up tilt and mental arithmetic stress on beat-to-beat variability of heart rate and QT interval, by computing sample entropy and cross-sample entropy.…”
mentioning
confidence: 99%
“…These results are also consistent with previous studies where cardiac Autonomous Nervous System (ANS) is impaired in frail elderly people, as indicated by a reduction in the complexity of HR dynamics, reduced HR variability, reduced HR changes in response to daily activities and is likely to be a consequence of a reduced vagal activity. Nevertheless, in this case the reduction is lower in symptomatic OI patients if we compared them with asymptomatic OI participants [ 40 , 41 ].…”
Section: Discussionmentioning
confidence: 99%