Enterocystoplasty Complications in Children. A Study of 30 Cases

Bertschy, Catherine; Bawab, F.; Liard, A; Valioulis, I.; Mitrofanoff, P

doi:10.1055/s-2008-1072319

Cited by 34 publications

(16 citation statements)

References 29 publications

(32 reference statements)

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“…Perforations have been reported in 6% to 13% of augmented patients [13][14][15][16], with our series having an 8.6% prevalence [13]. We found an increased risk with the use of sigmoid colon, but this may have been due to nondetubularization because others have found no increased risk with sigmoid [16].…”

Section: Spontaneous Bladder Perforationcontrasting

confidence: 69%

Bladder augmentation: Complications in the pediatric population

Metcalfe

Rink²

2007

Curr Urol Rep

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Bladder augmentation is an invaluable tool for the pediatric urologist, for both the protection of the upper urinary tract and attainment of urinary continence. However, it remains a major surgical undertaking with significant morbidity. This review examines the incidence and pathophysiology of some of the most common and serious complications, which include surgical complications, such as malignancy, bowel obstruction, and bladder perforation, and medical complications including urinary tract infections and gastrointestinal dysfunction. We review the most current and pertinent literature to provide a comprehensive and practical overview of complications from bladder augmentation in the pediatric population.

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Section: Spontaneous Bladder Perforationcontrasting

confidence: 69%

Bladder augmentation: Complications in the pediatric population

Metcalfe

Rink²

2007

Curr Urol Rep

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“…This percentage is within the range of other published data on bladder augments. Bertschy et al [7] reported on 28 children who had undergone bladder augmentation, and the UTI rate was 42%. Clark et al [3] reported an infection rate ranging from 19% to 63%, depending on degree of patient compliance with the catheterizing regimen.…”

Section: Discussionmentioning

confidence: 98%

Mitrofanoff continent catheterizable conduits: Top down or bottom up?

Berkowitz

North

Tripp

et al. 2009

Journal of Pediatric Urology

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“…There are several complications reported with the use of bowel as substitute [4] and these include electrolyte disturbances, urinary tract infections, bowel complications and malignancy. Malignancy has been reported in about 1.3% of these patients and is a cause of major concern among surgeons and patients [5].…”

Section: Discussionmentioning

confidence: 98%

Incorporation of Integra® in tissue defects: a pilot study in the rat model

et al. 2007

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Integra has been shown to be very useful in accelerating the growth of neodermis. It has found extensive use in case of burns as a primary dressing immediately after a burn, after release of contractures and following scar revision. It has been used to achieve cover after the debridement of extensive infective processes involving the skin. Encouraged by these results we have assessed the application of Integra to augment and/or patch defects of the urinary bladder, diaphragm and the abdominal wall in the rat model. This was a pilot study and involved the incorporation of Integra in the diaphragm, the urinary bladder (extramucosal) and the muscle layer of the abdominal wall. Eight adult Wistar rats were given general anaesthesia and Integra was implanted with absorbable sutures at the sites mentioned. The omentum was hitched to the collagen matrix surface to revascularise the graft. The silicone was left in situ. The operative period was covered with antibiotics. The anaesthesia was then reversed. Postoperatively the rats were given analgesia and feeds started immediately. The rats were sacrificed after 3 weeks. The abdominal cavity was examined for adhesions. The Integra implant along with adjacent tissue was harvested and examined histologically. There were no visible intra-abdominal adhesions. The histology revealed good degree of neovascularisation and fibrosis in and adjacent to the implant. This was comparable to the changes seen in the skin. This pilot study has shown that implanting Integra invokes a similar response in deeper tissues and it can develop neovascularisation from the omentum. Hence, this could find some application in treating congenital conditions such as diaphragmatic hernias, abdominal wall defects and for bladders requiring augmentation. Our initial results are quite encouraging and we feel that this field should be further explored.

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Enterocystoplasty Complications in Children. A Study of 30 Cases

Abstract: The complications presented in our patients confirm the view that they are associated with intestinal mucosa in the bladder and our study proves, once more, the current necessity to seek alternative tissues for bladder augmentation.

Cited by 34 publications

References 29 publications

Bladder augmentation: Complications in the pediatric population

Bladder augmentation: Complications in the pediatric population

Mitrofanoff continent catheterizable conduits: Top down or bottom up?

Incorporation of Integra® in tissue defects: a pilot study in the rat model

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