Enteric Amebiasis

Peterson, Kristine M.; Singh, Upinder; Petri, William A.

doi:10.1016/b978-0-7020-3935-5.00092-6

Cited by 12 publications

(7 citation statements)

References 168 publications

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Section: Resultsmentioning

confidence: 99%

“…The most sensitive serology assay is the indirect hemagglutination test (IHA) and is positive in up to 90% of patients with intestinal disease [43]. Unlike E. dispar , infection by E. histolytica results in the development of antibodies which can be detected within 5 to 7 days from acute infection [43]. However, up to 35% of individuals from endemic areas have persistent antibodies from previous infection; therefore, only a negative serology result can be helpful to exclude disease [26, 43].…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Entamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine Development

Kantor

Abrantes

Estevez

et al. 2018

Canadian Journal of Gastroenterology and Hepatology

152

116

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Entamoeba histolytica is the responsible parasite of amoebiasis and remains one of the top three parasitic causes of mortality worldwide. With increased travel and emigration to developed countries, infection is becoming more common in nonendemic areas. Although the majority of individuals infected with E. histolytica remain asymptomatic, some present with amoebic colitis and disseminated disease. As more is learned about its pathogenesis and the host's immune response, the potential for developing a vaccine holds promise. This narrative review outlines the current knowledge regarding E. histolytica and E. dispar and insight in the development of a vaccine.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Entamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine Development

Kantor

Abrantes

Estevez

et al. 2018

Canadian Journal of Gastroenterology and Hepatology

152

116

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show abstract

“…Liver function tests in all abscess etiologies reveal an elevated alkaline phosphatase and, sometimes, elevated aminotransferases. Serologic testing for E. histolytica is useful, since over 90% of infected patients have detectable antibodies at presentation, though they may be negative during the first week of infection [8]. Antibodies are more sensitive than antigen for detection.…”

Section: Discussionmentioning

confidence: 99%

A Tale of Two Cysts: Disparate Outcomes of Two Hepatic Cysts

Henry¹,

Dargan²

2016

J Med Microb Diagn

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Simple hepatic cysts occur in less than 5% of the population. As the technology we use for imaging advances, so does the frequency with which we identify them. Simple cysts, as presented here, do not generally require aspiration. The majority of these cysts do not require treatment, however, those larger than 4 cm are recommended for surveillance. We present two cases of simple cysts that were followed for 15 years and managed differently. The experience we acquired from these cases illustrates challenges in understanding and management and an implication that, perhaps, conservative surveillance might be best.

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“…Serum antibodies are detectable in 92 to 97% of patients at the time of presentation. 17 In endemic areas, up to 35% of uninfected individuals have antiamebic antibodies due to previous infection with E. histolytica. Therefore, negative serology is helpful for exclusion of disease, but positive serology cannot distinguish between acute and previous infection.…”

Section: Serology and Antigen Detectionmentioning

confidence: 99%

Amebic Abscess—Is It still a Common Entity?

Chaubal¹,

Pipaliya²,

Sawant³

2017

Journal of Gastrointestinal Infections

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Amebic liver abscess is the most common extraintestinal manifestation of amebiasis. It is seen most frequently in the fourth and fifth decades of life and is more common among adult men and alcoholics. The infection is primarily transmitted by food and water contamination. It presents commonly with fever and right hypochondriac pain but can present with complications like rupture into the pleural and peritoneal cavity or with abdominal vein thrombosis. The infection still responds well to nitroimidazoles, which remain the mainstay of treatment. In India, the epidemiology and presentation of amebic abscess have not changed over the years and it still is the major cause of liver abscesses.

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Enteric Amebiasis

Cited by 12 publications

References 168 publications

Entamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine Development

Entamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine Development

A Tale of Two Cysts: Disparate Outcomes of Two Hepatic Cysts

Amebic Abscess—Is It still a Common Entity?

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