Enteral nutrition in hypermetabolic surgical patients

Cerra, Frank B.; Shronts, Eva P.; Raup, Sandra; Konstantinides, Nancy N.

doi:10.1097/00003246-198907000-00004

Cited by 24 publications

(10 citation statements)

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“…Jeejeboy and Cerra proposed an alternative approach that uses body weight (kg) alone as a determining factor, and omits the variables of age, sex and height as used in HB equation. This type of assessment has proven to be accurate and efficient over time [33, 34]. Ireton-Jones and Owen et al have developed specific formulas for the obese patient, which is common in SCI subjects.…”

Section: Physiopathological Mechanisms Of Malnutrition In Acute and Cmentioning

confidence: 99%

Malnutrition in Spinal Cord Injury: More Than Nutritional Deficiency

Dionyssiotis¹

2012

J Clin Med Res

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Denervation of the spinal cord below the level of injury leads to complications producing malnutrition. Nutritional status affects mortality and pathology of injured subjects and it has been reported that two thirds of individuals enrolled in rehabilitation units are malnourished. Therefore, the aim should be either to maintain an optimal nutritional status, or supplement these subjects in order to overcome deficiencies in nutrients or prevent obesity. This paper reviews methods of nutritional assessment and describes the physiopathological mechanisms of malnutrition based on the assumption that spinal cord injured subjects need to receive adequate nutrition to promote optimal recovery, placing nutrition as a first line treatment and not an afterthought in the rehabilitation of spinal cord injury.

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Section: Physiopathological Mechanisms Of Malnutrition In Acute and Cmentioning

confidence: 99%

Malnutrition in Spinal Cord Injury: More Than Nutritional Deficiency

Dionyssiotis¹

2012

J Clin Med Res

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“…With a crude mortality of 35%, it is the number one killer in surgical intensive care units (2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13). Since the introduction of antibiotics 50 years ago, there has been no decline in the mortality of patients with sepsis.…”

Section: Introductionmentioning

confidence: 99%

Peptidoglycan and Lipoteichoic Acid in Gram-Positive Bacterial Sepsis: Receptors, Signal Transduction, Biological Effects, and Synergism

Wang¹,

Dahle²,

McDonald³

et al. 2003

Shock

136

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In sepsis and multiple organ dysfunction syndrome (MODS) caused by gram-negative bacteria, lipopolysaccharide (LPS) initiates the early signaling events leading to the deleterious inflammatory response. However, it has become clear that LPS can not reproduce all of the clinical features of sepsis, which emphasize the roles of other contributing factors. Gram-positive bacteria, which lack LPS, are today responsible for a substantial part of the incidents of sepsis with MODS. The major wall components of gram-positive bacteria, peptidoglycan and lipoteichoic acid, are thought to contribute to the development of sepsis and MODS. In this review, the literature underlying our current understanding of how peptidoglycan and lipoteichoic acid activate inflammatory responses will be presented, with a focus on recent advances in this field.

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“…Several other investigators reported that nutritional formulae containing immunonutrients such as glutamine, arginine, fish oil, probiotics, RNA, and menhaden oil could exert a significant positive effect on host defense mechanisms after severe injury (Cerra et al, 1983;Alexander et al . , 1986;Gottshlich et al, 1990;Gennari et al, 1995;Chakravarty et al, 2002;Bistrian, 2003;Choudhry et al, 2003;Chuntrasakul et al, 2003;McCowen and Bistrian, 2003;Kreymann et al, 2006;Peng et al, 2006;Calder, 2007).…”

Section: Discussionmentioning

confidence: 99%

“…As discussed earlier, the favorable concentration of glutamine in DEF-BP might have spared the deamination of BCAA. Many investigators have reported the role of BCAA in maintaining liver function in both human and animal models (Cerra et al, 1983;Ferency, 1996;Saleh et al, 2002;Charlton, 2006;.…”

Section: Discussionmentioning

confidence: 99%

“…The formulae enriched with BCAA help normalize the amino acid profile, improve protein synthesis, and maintain nitrogen balance (Ferenci, 1996). These products are often recommended for patients under major metabolic stress (Cerra et al, 1983;Mobarhan et al, 1990;Ferando et al, 1995). High-fat (up to 50%) enteral foods are advised to patients with chronic obstructive pulmonary disease (COPD) (Noller and Mobarhan, 1986).…”

Section: Disease-specific Formulaementioning

confidence: 99%

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Medical Foods from Natural Sources

Kaur¹

2009

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Enteral nutrition in hypermetabolic surgical patients

Cited by 24 publications

References 0 publications

Malnutrition in Spinal Cord Injury: More Than Nutritional Deficiency

Malnutrition in Spinal Cord Injury: More Than Nutritional Deficiency

Peptidoglycan and Lipoteichoic Acid in Gram-Positive Bacterial Sepsis: Receptors, Signal Transduction, Biological Effects, and Synergism

Medical Foods from Natural Sources

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