Enhancing Memory in Late-Life Depression: The Effects of a Combined Psychoeducation and Cognitive Training Program

Naismith, Sharon L.; Diamond, Keri; Carter, Phoebe E.; Norrie, Louisa; Redoblado-Hodge, Marie Antoinette; Lewis, Simon J.G.; Hickie, Ian B.

doi:10.1097/jgp.0b013e3181dba587

Cited by 94 publications

(79 citation statements)

References 32 publications

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“…Regarding the effects on everyday functioning, it must be taken into account that only two studies included in the meta-analysis assessed appropriate transfer measures [57,62]. Therefore, more studies assessing the effect of the CCT on everyday functioning are needed to confirm the positive findings in this meta-analysis.…”

Section: Cognitive Remediation Therapymentioning

confidence: 99%

“…The lack of significant effects for those two domains could either be attributed to methodological issues like highly heterogeneous measures or insufficient assessment. In fact, executive functioning was only targeted in one study during the last 2 weeks of training [57] and only one session of psycho-education in another [62]. However, it could also reflect valid difficulties in improving those two cognitive domains, which need to be theoretically discussed and taken into account when designing specific training approaches.…”

Section: Cognitive Remediation Therapymentioning

confidence: 99%

“…Only two clinical trials of this meta-analysis examined the impact of CCT on stable patients with MDD without psychotic symptoms [59,62]: Elgamal et al [59], for example, demonstrated improvement under CRT in several neuropsychological tests regarding attention, verbal learning and memory, psychomotor speed, and executive function in n = 12 outpatients with long-term illness with stable depressive symptom scores over a time period of ten weeks. Naismith et al [62] investigated n = 41 stabilized outpatients on medication with a lifetime history of major depression and depressive symptoms in the normal to mild range. Patients with the mean age of 64.8 years were randomized either to a waitlist or to an intervention group.…”

Section: Cognitive Remediation Therapymentioning

confidence: 99%

“…The training intensity also varied from 3 sessions over 2 weeks [58] to 64 sessions over 16 weeks [61]. Furthermore, only two of the included studies combined CCT with compensatory strategies [57,62]. Naismith et al [62] provided the intervention group with a psychoeducation training on health and cognitive functioning as already mentioned above, over a period of 10 weeks.…”

Section: Cognitive Remediation Therapymentioning

confidence: 99%

“…Furthermore, only two of the included studies combined CCT with compensatory strategies [57,62]. Naismith et al [62] provided the intervention group with a psychoeducation training on health and cognitive functioning as already mentioned above, over a period of 10 weeks. Bowie et al [57], however, supplemented the CCT with strategic self-monitoring training, bridging discussions to facilitate transfer to everyday behavior and 2 homework sessions per day, also over the period of 10 weeks.…”

Section: Cognitive Remediation Therapymentioning

confidence: 99%

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Cognitive Impairment Along the Course of Depression: Non-Pharmacological Treatment Options

et al. 2018

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Major Depressive Disorder (MDD) is one of the most common psychiatric disorders, with a large global impact on both the individual and the society. In this narrative review, we summarize neurocognitive deficits during acute and (partially) remitted states of depression. Furthermore, we outline the potential negative effect of cognitive impairment (CI) on functional recovery, and discuss the role of several variables in the development of CI for MDD patients. Though there is cumulating evidence regarding persistent CI in unipolar depression, research on treatment options specific for this patient group is still scarce. Hence the central aim of our review is to present non-pharmacological interventions, which are thought to reduce CI in affected MDD patients. We discuss cognitive remediation therapy (CRT), physical exercise, yoga, mindfulness-based therapy, and modern neuromodulation approaches like neurostimulation and neurofeedback training. In conclusion, we propose future directions for research on CI in depression. Looking further ahead, we suggest creative interventional designs that include a direct comparison of different non-pharmacological treatment approaches on neurocognition and functional outcome of MDD. Furthermore, additive and synergistic effects of CRT with other treatment approaches should be examined and compared to create multimodal and even personalized intervention programs.

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Section: Cognitive Remediation Therapymentioning

confidence: 99%

Section: Cognitive Remediation Therapymentioning

confidence: 99%

Section: Cognitive Remediation Therapymentioning

confidence: 99%

Section: Cognitive Remediation Therapymentioning

confidence: 99%

Section: Cognitive Remediation Therapymentioning

confidence: 99%

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Cognitive Impairment Along the Course of Depression: Non-Pharmacological Treatment Options

et al. 2018

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Memory Rehabilitation in Neurological Patients

Miller¹,

Radford²

2015

The Wiley Handbook on the Cognitive Neuroscience of Memory

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What role for cognitive remediation in the treatment of depressive symptoms? A superiority and noninferiority meta‐analysis for clinicians

Sociali

Borgi

Pettorruso

et al. 2022

Depression and Anxiety

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Background Cognitive remediation (CR) is a promising technique in the treatment of the cognitive dimension of depression. The present study evaluated the potential of CR in treating depressive symptoms and provides practical information about its usefulness in clinical settings. Methods We performed two meta‐analyses of published randomized (and nonrandomized) clinical trials, comparing CR to control conditions in subjects with current depressive symptomatology. The superiority meta‐analysis aimed to determine the superiority of CR when compared with placebo/waiting list interventions and its efficacy when used as an augmentation therapy. The noninferiority meta‐analysis determined whether CR had noninferior efficacy compared with standard antidepressant interventions. Results CR was found to significantly improve depressive symptomatology in the superiority meta‐analysis (CR: n = 466, control n = 478). Moreover, CR seemed to be noninferior to standard antidepressant interventions (CR: n = 230, control n = 235). CR was more effective when addressing hot (vs. cold) cognition, when involving younger patients (i.e., <30 years), and in the case of mild‐moderate (vs. severe) depression. Conclusions CR should be considered an augmentation treatment to improve treatment outcomes in depressed subjects, especially among young individuals. Interventions addressing hot cognition seem to be the most promising.

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Enhancing Memory in Late-Life Depression: The Effects of a Combined Psychoeducation and Cognitive Training Program

Cited by 94 publications

References 32 publications

Cognitive Impairment Along the Course of Depression: Non-Pharmacological Treatment Options

Cognitive Impairment Along the Course of Depression: Non-Pharmacological Treatment Options

Memory Rehabilitation in Neurological Patients

What role for cognitive remediation in the treatment of depressive symptoms? A superiority and noninferiority meta‐analysis for clinicians

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