Enhancement of the Tyrosinase Inhibitory Activity of Mori Cortex Radicis Extract by Biotransformation Using<i>Leuconostoc paramesenteroides</i>PR

Kim, Jung Sung; You, Hyun Ju; Kang, Hye Yoon; Ji, Geun Eog

doi:10.1271/bbb.111002

Cited by 10 publications

(13 citation statements)

References 37 publications

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“…4b ). Kim et al [ 54 ] reported that ethanolic extract of Cortex radicis bio-transformed by Leuconostoc paramesenteroides PR effectively enhanced the tyrosinase inhibitory activity by 6.5-fold in in vitro . Also Usuki et al [ 55 ] demonstrated that LAB and/or their derivatives have wide range of application in the development of skin-whitening and cosmetic products with antioxidant potential that could directly inhibit tyrosinase enzyme activity.…”

Section: Resultsmentioning

confidence: 99%

Characterization and pharmacological potential of Lactobacillus sakei 1I1 isolated from fresh water fish Zacco koreanus

et al. 2016

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BackgroundThere are still a large variety of microorganisms among aquatic animals which have not been explored for their pharmacological potential. Hence, present study was aimed to isolate and characterize a potent lactic acid bacterium from fresh water fish sample Zacco koreanus, and to confirm its pharmacological potential.MethodsIsolation of lactic acid bacteria (LAB) from fresh water fish samples was done using serial dilution method. Biochemical identification and molecular characterization of selected LAB isolate 1I1, based on its potent antimicrobial efficacy, was accomplished using API kit and 16S rRNA gene sequencing analysis. Further, 1I1 was assessed for α-glucosidase and tyrosinase inhibitory potential as well as antiviral efficacy against highly pathogenic human influenza virus H1N1 using MDCK cell line in terms of its pharmacological potential.ResultsHere, we first time report isolation as well as biochemical and molecular characterization of a lactic acid bacterium Lactobacillus sakei 1I1 isolated from the intestine of a fresh water fish Z. koreanus. As a result, L. sakei 1I1 exhibited potent antimicrobial effect in vitro, and diameter of zones of inhibition of 1I1 against the tested pathogens was found in the range of 13.32 ± 0.51 to 23.16 ± 0.32 mm. Also L. sakei 1I1 at 100 mg/ml exhibited significant (p < 0.05) α–glucosidase and tyrosinase inhibitory activities by 60.69 and 72.59 %, in terms of its anti-diabetic and anti-melanogenic potential, respectively. Moreover, L. sakei 1I1 displayed profound anti-cytopathic effect on MDCK cell line when treated with its ethanol extract (100 mg/ml), confirming its potent anti-viral efficacy against H1N1 influenza virus.ConclusionsThese findings reinforce the suggestions that L. sakei 1I1 isolated from the intestine of fresh water fish Z. koreanus might be a candidate of choice for using in pharmacological preparations as an effective drug.

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Section: Resultsmentioning

confidence: 99%

Characterization and pharmacological potential of Lactobacillus sakei 1I1 isolated from fresh water fish Zacco koreanus

et al. 2016

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“…The first study describes the use of cellulase to catalyze the deglycosylation reaction of ORV glucosides in a Veratrum patulum extract [ 138 ]. ORV could also be produced from mulberroside A in a Morus alba root extract through a hydrolytic reaction catalyzed by the enzyme Pectinex [ 139 , 140 ], as well as by the enzyme extract obtained from the acid bacterium Leuconostoc paramesenteroides [ 141 ].…”

Section: Productionmentioning

confidence: 99%

“…Inhibition of tyrosinase and related activities by ORV (1) 34,37,49,61,63,67,77,84,97,109,111,124,128,138,139,141,[148][149][150][151][152][153][154][155]. …”

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confidence: 99%

Oxyresveratrol: Sources, Productions, Biological Activities, Pharmacokinetics, and Delivery Systems

Likhitwitayawuid

2021

Molecules

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Oxyresveratrol has recently attracted much research attention due to its simple chemical structure and diverse therapeutic potentials. Previous reviews describe the chemistry and biological activities of this phytoalexin, but additional coverage and greater accessibility are still needed. The current review provides a more comprehensive summary, covering research from 1955 to the present year. Oxyresveratrol occurs in both gymnosperms and angiosperms. However, it has never been reported in plants in the subclass Sympetalae, and this point might be of both chemotaxonomic and biosynthetic importance. Oxyresveratrol can be easily obtained from plant materials by conventional methods, and several systems for both qualitative and quantitative analysis of oxyresveratrol contents in plant materials and plant products are available. Oxyresveratrol possesses diverse biological and pharmacological activities such as the inhibition of tyrosinase and melanogenesis, antioxidant and anti-inflammatory activities, and protective effects against neurological disorders and digestive ailments. However, the unfavorable pharmacokinetic properties of oxyresveratrol, including low water solubility and poor oral availability and stability, have posed challenges to its development as a useful therapeutic agent. Recently, several delivery systems have emerged, with promising outcomes that may improve chances for the clinical study of oxyresveratrol.

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“…There are different types of indigenous lactic acid bacteria (LAB) present in nature, and aquatic animals hold a plethora of potential LAB with probiotic properties (Balcazar et al, 2008). Currently, LAB are used as probiotics adhering number of beneficial properties such as antibacterial activity (Rather et al, 2013), antifungal activity (Rather et al, 2014), immune modulation (Kamiya et al, 2017, Kim et al, 2012, Kober and Bowe, 2015, Tsai et al, 2010), anti-obesity (Tsai et al, 2014), and anti-diabetic properties (Bajpai et al, 2016) and so on. Due to the production of metabolic characteristics, LAB are considered as novel bacteria for their applications in food and pharmaceutical industry.…”

Section: Introductionmentioning

confidence: 99%

Pharmaceutical significance of Leuconostoc mesenteroides KS-TN11 isolated from Nile Tilapia, Oreochromis niloticus

Paray

Rather

Khalid

et al. 2018

Saudi Pharmaceutical Journal

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Aquatic animals are known for their myriad of beneficial bacteria with diverse biologically active compounds. The current study was aimed to isolate and characterize potentially beneficial lactic acid bacteria from Nile Tilapia and evaluate their pharmaceutical applications. The fish samples were dissected and stomach, intestine, and gills were collected and serially diluted for the isolation of lactic acid bacteria (LAB) on BCP agar media. Identification of isolate was carried by biochemical and molecular characterization using API kit and 16S rRNA gene sequencing analysis, respectively. Further, KS-TN11 was assessed for α-glucosidase inhibitory potential using the chromogenic method. A lactic acid bacterium KS-TN11 was isolated from the stomach of Nile Tilapia and identified as . Effect of KS-TN11 on lipid accumulation in adipocytes was done by using Oil Red O staining. The isolate showed strong antibacterial activity against a number of pathogenic bacteria in vitro. In addition, KS-TN11 KS-TN11 (50 mg/ml and 100 mg/ml) tends to inhibit adipogenesis in 3T3-L1 adipocytes and thus may have possible anti-obesity effects. Moreover, KS-TN11 exhibited substantial α-glucosidase inhibitory activities by 41.33% at 50 mg/ml and 64% at 100 mg/ml, respectively. The bacterium showed potent antibacterial activity against a number of pathogenic bacteria; in addition to alpha-glucosidase activity, and inhibition of lipid accumulation in 3T3-L1 cell line. These results reinforce KS-TN11 as a novel bacterium with an impending pharmaceutical application.

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Enhancement of the Tyrosinase Inhibitory Activity of Mori Cortex Radicis Extract by Biotransformation UsingLeuconostoc paramesenteroidesPR

Cited by 10 publications

References 37 publications

Characterization and pharmacological potential of Lactobacillus sakei 1I1 isolated from fresh water fish Zacco koreanus

Characterization and pharmacological potential of Lactobacillus sakei 1I1 isolated from fresh water fish Zacco koreanus

Oxyresveratrol: Sources, Productions, Biological Activities, Pharmacokinetics, and Delivery Systems

Pharmaceutical significance of Leuconostoc mesenteroides KS-TN11 isolated from Nile Tilapia, Oreochromis niloticus

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