Enhancement of the liver histologic of broiler induced by irradiated chitosan (IC)

Mushawwir, Andi; Permana, Rega; Darwis, Darmawan; Puspitasari, Tita; Pengerteni, Dewi Sekar; Nuryanthi, Nunung; Suwarno, Nono

doi:10.1063/5.0066271

Cited by 6 publications

(4 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover, chitosan exhibited an ability to sequester anions and scavenge hydroxyl free radicals, hydrogen peroxide, and other ROS, forming flocculates that alleviate oxidative stress-induced harm [25]. Fourth, the fish dietary supplementation with chitosan had the potential to enhance hepatic RNA repair, bolster protein synthesis, and regulate nutrient absorption and utilization in fish [26,27]. Fifth, chitosan exhibited the potential to augment the enzymatic activity involved in lipid and protein metabolism, thereby facilitating the proficient synthesis of lipids and proteins [28,29].…”

Section: Discussionmentioning

confidence: 99%

Effects of Dietary Supplementation with Chitosan on the Muscle Composition, Digestion, Lipid Metabolism, and Stress Resistance of Juvenile Tilapia (Oreochromis niloticus) Exposed to Cadmium-Induced Stress

Zhang,

Xie,

Zhang

et al. 2024

Animals

View full text Add to dashboard Cite

The aim of this study was to investigate the effects of dietary chitosan supplementation on the muscle composition, digestion, lipid metabolism, and stress resistance, and their related gene expression, of juvenile tilapia (Oreochromis niloticus) subjected to cadmium (Cd2+) stress. Juvenile tilapia with an initial body weight of 21.21 ± 0.24 g were fed with a formulated feed containing five different levels (0%, 0.5%, 1.0%, 1.5%, and 2.0%) of chitosan for 60 days, while the water in all experimental groups contained a Cd2+ concentration of 0.2 mg/L. The results showed that, compared with the control group (0% chitosan), the contents of crude fat and crude protein in the muscle, the activities of lipase, trypsin, and amylase in the intestine, as well as the relative expression levels of metallothionein (mt), cytochrome P450 1A (cyp1a), carnitine palmitoyltransferase-1 (cpt-1), peroxisome proliferator-activated receptor alpha (pparα), peroxisome proliferator-activated receptor gamma (pparγ), hormone-sensitive lipase (hsl), lipoprotein lipase (lpl), malate dehydrogenase (mdh), leptin (lep), fatty acid synthase (fas), sterol regulatory element-binding protein 1 (srebp1), and stearoyl-CoA desaturase (scd) genes in the liver of juveniles were significantly increased (p < 0.05). In conclusion, dietary chitosan supplementation could alleviate the effects of Cd2+ stress on the muscle composition, digestive enzymes, lipid metabolism, and stress resistance, and their related gene expression, of juvenile tilapia, and to some extent reduce the toxic effect of Cd2+ stress on tilapia.

show abstract

Section: Discussionmentioning

confidence: 99%

Effects of Dietary Supplementation with Chitosan on the Muscle Composition, Digestion, Lipid Metabolism, and Stress Resistance of Juvenile Tilapia (Oreochromis niloticus) Exposed to Cadmium-Induced Stress

Zhang,

Xie,

Zhang

et al. 2024

Animals

View full text Add to dashboard Cite

show abstract

“…Likewise, Chang et al (2020) found a positive effect of chitosan in improving the growth performance and oxidative status of heat-stressed broiler chickens. Several other studies also found that chitosan increased liver metabolic activity in ruminants (Mushawwir et al, 2020), improved liver function and reduced liver inflammation in broiler (Mushawwir et al, 2021), and native chicken (Hanifah et al, 2022), and effectively prevents lipogenesis in native chicken (Kharazi et al, 2022).…”

Section: Introductionmentioning

confidence: 92%

Growth and Haematological Response of Broilers Raised at High-Density Pens and Fed Germinated Papaya Seed and Chitosan Blend

Sugiharto¹,

Agusetyaningsih²,

Widiastuti³

et al. 2022

JAHP

View full text Add to dashboard Cite

The study investigated the effects of germinated papaya seed and a mixture of germinated papaya seed and chitosan on growth and haematological parameters in broilers stocked in high-density pens from 15 to 28 days old. A total of 490 broiler chicks were distributed into four groups, including CONT (chicks receiving basal feed and raised under normal density [10 chicks per m 2 ]), HSD (chicks receiving basal feed and raised under high density [20 chicks per m 2 ]), HSD-P (chicks receiving 0.5% germinated papaya seed flour and raised under high density) and HSD-PC (chicks receiving 0.5% germinated papaya seed flour and 0.2% chitosan, and raised in high-density condition). Growth and feed intake were measured weekly, while blood was collected on day 28. Despite being lower (P < 0.05) than CONT, HSD-P and HSD-PC chickens consumed more (P < 0.05) feed than HSD chickens. Body weight and weight gain were lower (P < 0.05) in HSD compared to the CONT, HSD-P and HSD-PC groups. The European Production Higher Efficiency Factor (EPEF) tended (P = 0.06) to be higher in HSD-PC than in HSD chicks. While there was no significant effect of the treatments on complete blood counts and serum biochemical parameters, serum creatinine concentration was higher (P < 0.05) in HSD and HSD-P than in CONT and HSD-PC. In conclusion, germinated papaya seeds or a mixture of germinated papaya seeds and chitosan improved broiler production performance and kidney health while alleviating muscle protein catabolism in high-density pens from days 15 to 28.

show abstract

“…Still, they are used by muscle cells and other tissues for tissue biosynthesis (Lakhssassi et al 2021). Several research reports also show that this increase in free fatty acids simultaneously stimulates β-oxidation activity (Hernawan et al 2017;Toral et al 2022) and the formation of acetyl-CoA from the fatty acid pathway (Lakhssassi et al 2021), as well as increases oxidation-reduction activity in mitochondria (Mushawwir et al 2021a;Mushawwir et al 2021b). This metabolic fact can also be why a decrease in TAG is accompanied by a decrease in NEFA based on the results of this study (84.36 without legume to 69.43,71.57,and 72.31 with BS+K,BS+L,and BS+M,respectively).…”

Section: Lipid Regulationmentioning

confidence: 99%

Impact of protein source from legume forages on lipid regulation and growth on native ram lambs reared extensively in the south coast of West Java, Indonesia

TANUWIRIA,

MUSHAWWIR,

ZAIN

et al. 2023

Biodiversitas

View full text Add to dashboard Cite

Abstract. Tanuwiria UH, Mushawwir A, Zain M, Despal D. 2023. Impact of protein source from legume forages on lipid regulation and growth on native ram lambs reared extensively in the south coast of West Java, Indonesia. Biodiversitas 24: 4183-4192. This investigation was carried out in three different locations to examine the impact of legume forage as a protein source on lipid regulation and growth. This study used 120 rams, consisting of 40 rams in each location (Garut, Cianjur, Sukabumi) spread along the South Coast of West Java. Physical environmental conditions were recorded during the study. Ram lambs at each location were divided into four groups; one group only received a basal diet (Setaria/Setaria sphacelata), and the other three groups were each given additional legumes (calliandra/Calliandra calothyrsus, lamtoro/Leucaena leucocephala, and moringa/Moringa oleifera). Blood samples were collected every two weeks during the 16 weeks experiment. The blood sampling was handled based on standard procedures to prevent sample damage, and the body weight was measured every two weeks. Sample analysis related to lipid regulation and creatine kinase activity was measured using spectrophotometric techniques according to the instructions of the Kit Randox protocol and analysis of blood plasma fatty acids were analyzed by gas chromatography. The research results show that legumes as a protein source can regulate through molecular signaling to decrease lipid levels, saturated fatty acids, and lipid transport in the extracellular fluid, but increase unsaturated fatty acid and the growth rate of ram lambs. Based on the results of the current study, it can be a strong basis for the development of nutrigenomic aspects of protein for small ruminants, accompanied by studies of the ages of different ruminant samples.

show abstract

Enhancement of the liver histologic of broiler induced by irradiated chitosan (IC)

Cited by 6 publications

References 36 publications

Effects of Dietary Supplementation with Chitosan on the Muscle Composition, Digestion, Lipid Metabolism, and Stress Resistance of Juvenile Tilapia (Oreochromis niloticus) Exposed to Cadmium-Induced Stress

Effects of Dietary Supplementation with Chitosan on the Muscle Composition, Digestion, Lipid Metabolism, and Stress Resistance of Juvenile Tilapia (Oreochromis niloticus) Exposed to Cadmium-Induced Stress

Growth and Haematological Response of Broilers Raised at High-Density Pens and Fed Germinated Papaya Seed and Chitosan Blend

Impact of protein source from legume forages on lipid regulation and growth on native ram lambs reared extensively in the south coast of West Java, Indonesia

Contact Info

Product

Resources

About