Enhancement of glucose oxide electron-transfer mechanism in glucose biosensor via optimum physical chemistry of functionalized carbon nanotubes

Abstract

<jats:title>Abstract</jats:title><jats:p>Nanostructures are a viable candidate for the construction of simple blood sugar monitoring devices. Electrochemical oxidation based on the immobilization of glucose oxidase (GOx) on carbon nanostructures has paved the way for a modern approach to the determination of glucose levels in blood. Carbon nanotubes (CNTs) exhibit excellent electrical properties, resulting in increased interest in glucose biosensors based on CNTs. Its large surface area and optimum aspect ratio increase the total amount of immobilized biomaterials onto its surface. In this contribution, recent advances in the development of reliable methods to improve the electron-transfer mechanism of GOx in CNT-based glucose biosensors are highlighted. Moreover, mass production and growth mechanism of purified CNTs by chemical vapor deposition were discussed by emphasizing its growth-control aspects.</jats:p>

Development of Frequency Based Taste Receptors Using Bioinspired Glucose Nanobiosensor

“…Moreover, the type III cell received the output pulses generated by the type II cell. The sum of neural pulses emitted by independent sources showed an exponential-like distribution of interpulse intervals in the first layer 13 , 25 . In other words, the concentration of glucose is detected by the electrochemical glucose biosensor attached to the type II cells, which are responsible to record the alteration in the biosensor resistance and then transduce to the type III cells.…”

“…Previously, we reported the successful fabrication of an electrochemical enzymatic glucose biosensor using a carbon nanotube composite. Furthermore, a comparative review on enzymatic glucose biosensors using electrochemical methods, especially those fabricated by functionalisation of the carbon nanotube (CNTs) 12 surface with glucose oxidase (GOx) 13 , was published. In this study, we developed a method to fabricate a bioinspired nanobiosensor for glucose diagnoses following the mouse taste bud network 14 .…”

Progress in Carbon Nanotube-Based Electrochemical Biosensors – A Review

“…The conductivity of nanocomposites enhances electron transfer between the active centres of enzymes and electrodes so that the particles act as electron transfer conduits or mediators (Luong et al, 2017;Muguruma et al, 2017, Termehyousefi et al, 2017. Conductive polymer-CNT nanocomposites have improved the operational characteristics such as selectivity, stability, or sensitivity of the resulting biosensors (Shrivastava et al, 2016;Punetha et al, 2017).…”

“…Direct electrochemistry of GOx involves DET between the electrode and the active centre of the GOx (Yu et al, 2014;, Luong et al, 2017, Muguruma et al, 2017Termehyousefi et al, 2017;Xia et al, 2017) (Fig. 6).…”

“…Different electroanalytical techniques have been employed for the development of CNTs electrochemical biosensors for the detection and quantification of many biomolecular species (Dervisevic et al, 2017;Uwimbabazi et al, 2017;, chemical compounds, inorganic ions in environmental and biological samples (Braga et al, 2015;Cui et al, 2015). Various CNTs electrochemical biosensors have been developed for detecting and quantification of medically and pharmaceutically important compounds such as glucose (Shrestha et al, 2016;Song et al, 2017;Surucu & Abaci, 2017;Termehyousefi et al, 2017, Uwimbabazi et al, 2017Zhou et al, 2017;Jiang et al, 2018), acetaminophen (Alam et al, 2018), methylglyoxal, H2O2 (Hamidi & Haghighi, 2016;Sánchez-Tirado et al, 2017), metal ions (Moyo et al, 2014a;Somayeh, et al, 2017), DNA (Fu et al, 2017;Hien et al, 2017;Huang et al, 2017) (Chiorcea-Paquim, et al, 2017Unal et al, 2017), ascorbic acid (Deb et al, 2016;Hu et al, 2016), uric acid (Erden et al, 2015;Ghodsi et al, 2015;Sun et al, 2015;Hu et al, 2016;Yang et al, 2016), Nicotinamide Adenine Dinucleotide (NADH) Mutyala & Mathiyarasu 2016;Atta et al, 2017), acetaminophen (Cernat et al, 2015;Moretti et al, 2016), herbicides (Szabó et al, 2017) and pesticides Liu et al, 2016;…”