Enhancement of fracture toughness in bioactive glass-based nanocomposites with nanocrystalline forsterite as advanced biomaterials for bone tissue engineering applications

Effect of ciprofloxacin incorporation in PVA and PVA bioactive glass composite scaffolds

“…In the produced scaffolds, a marked change could be observed, as the amount of glass and drug increased the compressive strength increase. The incorporation of SG-B into PVA polymer enhances the compressive strength, due to their small particle size and large surface area which results in great attachment of SG-B particles to the polymer matrix as reported before [33][34][35][36][37][38]. from alkyl chain backbone [42][43][44][45].…”

“…As the glass content increases the porosity decreases and the pore walls becomes thicker. Among several processing techniques, the freeze drying method was chosen since it could provide easy control of the pore structure [33]. The co-existence of macropores and micropores is not only favorable for the ingrowth of cells and new tissue but also beneficial to the exchange of nutrients and metabolic waste [34].…”

Surface modification of stainless steel implants using nanostructured forsterite (Mg2SiO4) coating for biomaterial applications

“…Forsterite as a biocompatible material have in vitro bioactivity, better mechanical properties compared to the hydroxyapatite, and can be applicable as a new biomaterial for hard tissue repairs [7,9]. Moreover, fracture toughness of forsterite is close to that of the natural bone [10].…”

Development and degradation behavior of magnesium scaffolds coated with polycaprolactone for bone tissue engineering

“…TE scaffolds are mostly made by ceramics, polymers and hydrogels [2,3,5]. However, lack of mechanical strength in these materials is the main concern in the applicability of the produced scaffolds especially for bone TE [6,7]. Scientists have tailored several materials as both nanoparticles and bulk materials for various biomedical applications [8].…”