Enhanced SPR sensing based on micro-patterned thin films

Nanostructured plasmonic chips employing nanopillar and nanoring hole arrays for enhanced sensitivity of SPR-based biosensing

“…The optimal result showed a two-fold greater sensitivity which was deduced from the detection of 100 nM of IgG SPR signal when 4 layers of Au and Ag (2 each) were interrogated in Kretschmann configuration SPR setup. 34 The refractive index sensitivity of nanostructured substrates consisting of microhole arrays 35 embedded in a gold film was twice that of a conventional thin Au film substrate. Live et al 36 also demonstrated that SPR sensing could be enhanced by establishing a resonance condition between propagating and localized SP modes on microhole arrays by tuning the incident angle of light.…”

“…27–32 Improvement in SPRi for the detection of DNA hybridization was achieved by the Tabrizian group by modifying the conventional SPR setup with periodic gold nanoposts. 33 Live et al 34 described biosensors based on SPR with enhanced sensitivity by interrogating micro-patterned plasmonic thin films of gold and silver in the conventional Kretschmann configuration. The optimal result showed a two-fold greater sensitivity which was deduced from the detection of 100 nM of IgG SPR signal when 4 layers of Au and Ag (2 each) were interrogated in Kretschmann configuration SPR setup.…”