Spin-orbit coupling (SOC) is a key interaction in spintronics, allowing an electrical control of spin or magnetization and, vice versa, a magnetic control of electrical current. However, recent advances have revealed much broader implications of SOC that is also central to the design of topological states, including topological insulators, skyrmions, and Majorana fermions, or to overcome the exclusion of two-dimensional ferro-magnetism expected from the Mermin-Wagner theorem. SOC and the resulting emergent interfacial spin-orbit fields are simply realized in junctions through structural inversion asymmetry, while the anisotropy in magnetoresistance (MR) allows for their experimental detection. Surprisingly, we demonstrate that an all-epitaxial ferromagnet/ MgO/metal junction with only a negligible MR anisotropy undergoes a remarkable transformation below the superconducting transition temperature of the metal. The superconducting junction has a three orders of magnitude higher MR anisotropy and supports the formation of spin-triplet superconductivity, crucial for superconducting spintronics, and topologically-protected quantum computing. Our findings call for revisiting the role of SOC in other systems which, even when it seems negligible in the normal state, could have a profound influence on the superconducting response.For over 150 years magnetoresistive effects have provided attractive platforms to study spin-dependent phenomena and enable key spintronic applications [1]. Primarily, spintronics relies on junctions with at least two ferromagnetic layers to provide sufficiently large magnetoresistance (MR). Record room-temperature MR and commercial applications employ junctions of common ferromagnets, such as Co and Fe with MgO tunnel barrier [2,3]. Alternatively, MR occurs in single ferromagnetic layers with an interplay of interfacial spin-orbit coupling (SOC). However, in metallic systems this phenomenon, known as the tunneling anisotropic MR (TAMR) [4], is typically < 1% and precludes practical applications. Here we show experimentally that a negligible MR in an all-epitaxial ferromagnet/MgO/metal junction is drastically enhanced below the superconducting transition temperature of the metal. We explain this peculiar behavior with the role of the interfacial SOC in the formation of spin-triplet superconductivity which can enable low-power superconducting spintronics [5-7] and topologically-protected quantum computing [8,9].