Enhanced skeletal muscle glycogen repletion after endurance exercise is associated with higher plasma insulin and skeletal muscle hexokinase 2 protein levels in mice: comparison of level running and downhill running model

Takahashi, Yumiko; Sarkar, Juli; Yamada, Jumpei; Matsunaga, Yasushi; Nonaka, Yasunobu; Banjo, Mai; Sakaguchi, Ryo; Shinya, Terunaga; Hatta, Hideo

doi:10.1007/s13105-021-00806-z

Cited by 8 publications

(6 citation statements)

References 42 publications

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“…As is wellknown, milk with Ultra High Temperature has been made safe for eating for a very long time and flavored in a number of ways. Milk's glucose content is vital for glycogen recovery after exercise, as glycogen loss in the muscles during exercise induces the development of plasma insulin and protein content [35]. Findings of this investigation were in line with previous studies.…”

Section: Discussionsupporting

confidence: 90%

Effects of intense workout trials and milk intervention on decrease surrogate markers of metabolic syndrome

Mulyawan

Sumaryanti

Nugroho

et al. 2023

Fiz Pol

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Surrogate markers of metabolic syndrome complications is high levels of glucose and/or cholesterol in the blood. The purpose of this research is to determine whether or not various intensity exercise has a beneficial impact on blood glucose and cholesterol levels in young adults. As a consequence, this study was investigated about how exercise's influence on lowering the risk of metabolic diseases may be moderated by other factors, including by milk intake. Studies were conducted using a quasi-experimental, single-blind research design. Thirty-five participants were randomly assigned to one of four groups: control (C), moderate intensity (M), high intensity (H), or intermittent (I). The Sysmex XN-1000 is used for checking blood content, while the Cobas Pro is used to analyze blood chemistry in the lab. Using tools like the analysis of variance (ANOVA), the Mann-Whitney test, and the Pearson correlation coefficient, researchers may gauge the importance of inherent correlations and examine how group-level phenomena and interactions affect those coefficients. To sum up, we found that there was a statistically significant difference in glucose levels between the control group and the experimental group (p = 0.012 < 0.05), yet this difference was accompanied by a negative trend showing a rise in content. Also, there was a favorable tendency toward lower glucose and cholesterol levels across all compositions, while it was not statistically significant (p value > 0.05). To sum up, practically all of the variables point to a favorable tendency that that does not statistically significant – in the effect of exercise intensity combined with milk consumption. Exercise and milk intervention have been shown to have positive impacts, but further investigation or longer training sessions are needed to determine their true magnitude.

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Section: Discussionsupporting

confidence: 90%

Effects of intense workout trials and milk intervention on decrease surrogate markers of metabolic syndrome

Mulyawan

Sumaryanti

Nugroho

et al. 2023

Fiz Pol

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“…Whereas males reduced their cumulative force profile during recovery, females maintained levels similar to those prior to exercise. Finally, fat-fed males showed a negative correlation between grip strength and fasting glucose levels, but females did not; it will be interesting to determine if this sex difference is associated with the sensitized recovery of skeletal muscle glycogen 48 in females.…”

Section: Discussionmentioning

confidence: 99%

Simultaneous monitoring of mouse grip strength, force profile, and cumulative force profile distinguishes muscle physiology following surgical, pharmacologic and diet interventions

Munier

Pank

Severino³

et al. 2022

Sci Rep

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Grip strength is a valuable preclinical assay to study muscle physiology in disease and aging by directly determining changes in muscle force generation in active laboratory mice. Existing methods to statistically evaluate grip strength, however, have limitations in the power and scope of the physiological features that are assessed. We therefore designed a microcontroller whose serial measure of resistance-based force enables the simultaneous readout of (1) peak grip strength, (2) force profile (the non-linear progress of force exerted throughout a standard grip strength trial), and (3) cumulative force profile (the integral of force with respect to time of a single grip strength trial). We hypothesized that muscle pathologies of different etiologies have distinct effects on these parameters. To test this, we used our apparatus to assess the three muscle parameters in mice with impaired muscle function resulting from surgically induced peripheral pain, genetic peripheral neuropathy, adverse muscle effects induced by statin drug, and metabolic alterations induced by a high-fat diet. Both surgically induced peripheral nerve injury and statin-associated muscle damage diminished grip strength and force profile, without affecting cumulative force profile. Conversely, genetic peripheral neuropathy resulting from lipin 1 deficiency led to a marked reduction to all three parameters. A chronic high-fat diet led to reduced grip strength and force profile when normalized to body weight. In high-fat fed mice that were exerted aerobically and allowed to recover for 30 min, male mice exhibited impaired force profile parameters, which female mice were more resilient. Thus, simultaneous analysis of peak grip strength, force profile and cumulative force profile distinguishes the muscle impairments that result from distinct perturbations and may reflect distinct motor unit recruitment strategies.

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“…Then, it ends with the electron transfer phase in the aerobic cycle to produce adenosine triphosphate (ATP) (Jeukendrup, 2011;Kreider et al, 2017;Potgieter, 2013), which is employed as a basic ingredient for energy production in the body. Previous research emphasized that in sports where endurance was dominant, athletes would experience an increase in plasma insulin (Takahashi et al, 2021). In other words, when plasma insulin increases, glucose absorption automatically accelerates, which will impact reducing the amount of glucose in the blood because it is used as fuel during muscle contractions (Jelstad et al, 2021).…”

Section: Resultsmentioning

confidence: 99%

An exploration of the correlation between stress and blood glucose levels in athletes: Strategies for maintaining peak performance

Haryanto,

Saputra,

Muzaffar

2024

j. Sport Area

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Background Problems: Stress can cause a person to experience an accumulated risk of increased cholesterol and negatively impact performance in the field, as indicated by a decrease in blood glucose levels. Research Objectives: This research aims to identify the relationship between stress and blood glucose levels to find solutions for athletes to maintain glucose levels when competing. Methods: The research method was cross-sectional with an observational study approach. Glucose levels were assessed using an Accu-Chek device, while anxiety levels were assessed using the Perceived Stress Scale (PSS) questionnaire. The research subjects were 130 Provincial Training Camp (PELATPROV) athletes with an average age of 25.01 ± 5.15 years old, a weight of 64.15 ± 7.93 kg, a height of 171.21 ± 5.88 cm, and a BMI of 21.98 ± 3.71 kg/m2. Findings and Results: The results indicated significant differences in stress (0.001 < 0.05) and blood glucose levels (0.001 < 0.05) between the two groups. The pre-PON athlete group dominated the increase in stress and decrease in blood glucose levels compared to the non-Pre-PON group. Thus, this research has provided evidence of a correlation between stress levels and decreased blood glucose levels. Conclusion: Psychological and physiological aspects were proven to have an inevitable correlation. Athletes and coaches must communicate more deeply about the expected treatment during the preparation period, during and after the match, to understand each other’s needs to achieve performance. Therefore, athletes’ performance can be maintained well during competition and training.

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Enhanced skeletal muscle glycogen repletion after endurance exercise is associated with higher plasma insulin and skeletal muscle hexokinase 2 protein levels in mice: comparison of level running and downhill running model

Cited by 8 publications

References 42 publications

Effects of intense workout trials and milk intervention on decrease surrogate markers of metabolic syndrome

Effects of intense workout trials and milk intervention on decrease surrogate markers of metabolic syndrome

Simultaneous monitoring of mouse grip strength, force profile, and cumulative force profile distinguishes muscle physiology following surgical, pharmacologic and diet interventions

An exploration of the correlation between stress and blood glucose levels in athletes: Strategies for maintaining peak performance

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