Enhanced Sensitivity for Detection of Plasmodium falciparum gametocytes by magnetic nanoparticles combined with enzyme substrate system

Tangchaikeeree, Tienrat; Sawaisorn, Piamsiri; Somsri, Sangdao; Polpanich, Duangporn; Putaporntip, Chaturong; Tangboriboonrat, Pramuan; Udomsangpetch, Rachanee; Jangpatarapongsa, Kulachart

doi:10.1016/j.talanta.2016.10.106

Cited by 9 publications

(2 citation statements)

References 43 publications

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“…The size of MNPs is dependent on the following factors: the proportion of iron salt, type of salt and alkaline substance, mixing rate, pH, presence of nitrogen, and the temperature. MNPs are rapidly oxidized in the presence of oxygen and water causing precipitation and reduction in magnetic properties of nanoparticles [23][24][25]. An effective technique to prevent this is creating a layer of particles such as silica, amine, carboxyl, thiol, gold, and silver on them and forming a core-layer structure [26][27][28][29].…”

Section: Introductionmentioning

confidence: 99%

Enhanced sensitivity and efficiency of detection of Staphylococcus aureus based on modified magnetic nanoparticles by photometric systems

Naderlou

Salouti

Amini

et al. 2020

Artificial Cells, Nanomedicine, and Biotechnology

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Staphylococcus aureus is an important infectious factor in the food industry and hospital infections. Many methods are used for detecting bacteria but they are mostly time-consuming, poorly sensitive. In this study, a nano-biosensor based on iron nanoparticles (MNPs) was designed to detect S. aureus. MNPs were synthesized and conjugated to Biosensors. Then S. aureus was lysed and nano-biosensor (MNP-TiO 2 -AP-SMCC-Biosensors) was added to the lysed bacteria. After bonding the bacterial genome to the nano-biosensor, MNPs were separated by a magnet. Bacterial DNA was released from the surface of nano-biosensor and researched by Nano-drop spectrophotometry. The results of SEM and DLS revealed that the size of MNPs was 20-25 nm which increased to 38-43 nm after modification and addition of biosensors. The designed nano-biosensor was highly sensitive and specific for the detection of S. aureus. The limit of detection (LOD) was determined as 230 CFU mL À1 . There was an acceptable linear correlation between bacterial concentration and absorption at 3.7 Â 10 2 -3.7Â 10 7 whose linear diagram and regression was Y ¼ 0.242X þ 2.08 and R 2 ¼ .996. Further, in the presence of other bacteria as a negative control, it was absolutely specific. The sensitivity of the designed nano-biosensor was investigated and compared through PCR.

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Section: Introductionmentioning

confidence: 99%

Enhanced sensitivity and efficiency of detection of Staphylococcus aureus based on modified magnetic nanoparticles by photometric systems

Naderlou

Salouti

Amini

et al. 2020

Artificial Cells, Nanomedicine, and Biotechnology

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“…To address this problem various functionalized magnetic polymer nanoparticles, such as magnetic nanoparticles modied with hydrazine functionalized polymer, uorescent chitosan functionalized magnetic polymeric nanoparticles and epoxy-functionalized magnetic poly(divinylbenzene-co-glycidyl methacrylate) particles (mPDGs), were utilized. [20][21][22] By reason of their properties, along with highly specic surface areas and versatile surface functionality, these particles can be used widely as carriers for biomolecules including proteins, antibodies and antigens. [23][24][25] Moreover, a great advantage of using magnetic nanoparticles is the rapidity of separation upon applying an external magnetic eld, a one-step process which can avoid many of the timeconsuming steps of other separation processes.…”

Section: Introductionmentioning

confidence: 99%

Enrichment of human Vγ9Vδ2 T lymphocytes by magnetic poly(divinylbenzene-co-glycidyl methacrylate) colloidal particles conjugated with specific antibody

et al. 2018

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Nanotechnology for Therapy of Zoonotic Diseases: A Comprehensive Overview

et al. 2022

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Zoonotic infections belong to multiple infectious diseases transferred from animals to humans. Now, the treatment and diagnosis of zoonotic infections are perplexing due to genetic mutations, target site modifications, and multi‐drug resistance. Despite their benefits, most diagnostic molecular techniques have certain limits in terms of repeatability and sensitivity, mainly due to the heterogeneity among the diverse family of zoonotic pathogens. Therefore, developing more efficient and cost‐effective theranostics tools is the need of the hour to address these concerns. For this purpose, nanotechnology has revolutionized medicine with versatile potential capabilities for diagnosing and treating zoonosis via the targeted and controlled delivery of antimicrobial drugs via binding to the overexpressed infectious macrophages. Massive advancements have been made in fabricating novel nano‐based formulations to control zoonosis based on the use of poly(ethylenimine)‐conjugated nanomicelles, mannosylated thiolated chitosan (MTC)‐coated PM‐loaded PLGA NPs, mannose linked thiolated nanocarriers, adjuvanted pDNA hydrogel, arginine‐based nanocarriers, quantum dots to treat and diagnose a wide range of zoonotic diseases, including zoonotic influenza, salmonellosis, leishmaniasis, rabies, brucellosis, Lyme Disease, tuberculosis, and other infections caused by West Nile Virus, emerging coronaviruses (SARS, MERS, COVID‐19), in a preferentially targeted way. Recently developed anti‐pathogen loaded‐nanoformulations with enhanced cellular uptake, biocompatibility, and hemocompatibility have shown the ability to cross biological barriers when orally administrated. Therefore, this article reviewed the latest milestones and future growth areas in the field of efficient theranostics platforms to manage zoonotic infections.

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Enhanced Sensitivity for Detection of Plasmodium falciparum gametocytes by magnetic nanoparticles combined with enzyme substrate system

Cited by 9 publications

References 43 publications

Enhanced sensitivity and efficiency of detection of Staphylococcus aureus based on modified magnetic nanoparticles by photometric systems

Enhanced sensitivity and efficiency of detection of Staphylococcus aureus based on modified magnetic nanoparticles by photometric systems

Enrichment of human Vγ9Vδ2 T lymphocytes by magnetic poly(divinylbenzene-co-glycidyl methacrylate) colloidal particles conjugated with specific antibody

Nanotechnology for Therapy of Zoonotic Diseases: A Comprehensive Overview

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