Enhanced protein adsorption and patterning on nanostructured latex-coated paper

Juvonen, Helka; Määttänen, Anni; Ihalainen, Petri; Sarfraz, Jawad; Peltonen, Jouko

doi:10.1016/j.colsurfb.2014.03.050

Cited by 14 publications

(4 citation statements)

References 85 publications

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“…Details on the fabrication and application of nanostructured latex-coated papers have been given elsewhere [17,18]. In brief, two latex components with different glass transition temperatures (Tg) were used.…”

Section: Latex-coated Paper Substratementioning

confidence: 99%

Electro-Optical Gas Sensor Consisting of Nanostructured Paper Coating and an Ultrathin Sensing Element

et al. 2019

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This work describes the use of a paper substrate for electro-optical detection of toxic hydrogen sulfide (H2S) gas. For electrical detection, a chemiresistive type of gas sensor was developed. Ultrathin gold film electrodes (UTGFE) were produced by physical vapor deposition of gold on nanostructured latex-coated paper substrate. The gas-sensing film was deposited on the electrodes by inkjet printing. The sensing films were characterized by atomic force microscopy, X-ray photoelectron spectroscopy and conductometry. The sensing films showed more than seven orders of magnitude change in resistance when exposed to as low as 1 part per million (ppm) H2S gas at room temperature. Besides resistive response, the change in color of the sensing films was studied on a paper substrate, both as a function of print density of the sensing material and H2S concentration. For quantification of the analyte the red, green and blue color deconvolution was performed on the pictures of the paper strip indicator using an open source software. A clear response was obtained from the blue channel. The inexpensive disposable color strips produced on the paper substrate can be used for qualitative and quantitative detection (as low as 1.5 ppm) of H2S gas.

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Section: Latex-coated Paper Substratementioning

confidence: 99%

Electro-Optical Gas Sensor Consisting of Nanostructured Paper Coating and an Ultrathin Sensing Element

et al. 2019

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“…Tailored paper substrates with optimized roughness, surface energy, and porosity have been developed on which optical, electrical, and electrochemical sensors have been successfully demonstrated . Key properties of a print substrate controlling the ink‐setting (spreading and adsorption/absorption) are roughness, surface energy, charge, critical surface tension, and porosity . Equally important is to pay attention to the ink formulation, its composition, surface tension, rheology, and colloidal stability .…”

Section: Technologies and Materials For Tailor‐made Drug Delivery/diamentioning

confidence: 99%

“…Recent reports show that surface topography (roughness) and chemistry (surface energy, polar and dispersive components) have an effect on cell growth . Likewise, proteins intermediating cell adhesion and proliferation adhere selectively to surfaces of varying charge, hydrophilicity, and contact potential . Besides these passive ways of controlling cell adhesion and growth, a step toward active control and stimuli can be taken by combining printed electrodes and fluidic operations.…”

Section: Technologies and Materials For Tailor‐made Drug Delivery/diamentioning

confidence: 99%

Tailored Approaches in Drug Development and Diagnostics: From Molecular Design to Biological Model Systems

Sahlgren

Meinander

Zhang

et al. 2017

Adv Healthcare Materials

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Approaches to increase the efficiency in developing drugs and diagnostics tools, including new drug delivery and diagnostic technologies, are needed for improved diagnosis and treatment of major diseases and health problems such as cancer, inflammatory diseases, chronic wounds, and antibiotic resistance. Development within several areas of research ranging from computational sciences, material sciences, bioengineering to biomedical sciences and bioimaging is needed to realize innovative drug development and diagnostic (DDD) approaches. Here, an overview of recent progresses within key areas that can provide customizable solutions to improve processes and the approaches taken within DDD is provided. Due to the broadness of the area, unfortunately all relevant aspects such as pharmacokinetics of bioactive molecules and delivery systems cannot be covered. Tailored approaches within (i) bioinformatics and computer‐aided drug design, (ii) nanotechnology, (iii) novel materials and technologies for drug delivery and diagnostic systems, and (iv) disease models to predict safety and efficacy of medicines under development are focused on. Current developments and challenges ahead are discussed. The broad scope reflects the multidisciplinary nature of the field of DDD and aims to highlight the convergence of biological, pharmaceutical, and medical disciplines needed to meet the societal challenges of the 21st century.

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“…Moreover, it is important to keep the protein in its native state and in its physiological environment as well as refraining from any kind of damage and mechanical stress. Most of the current protein patterning methods [12][13][14][15][16][17][18][19][20][21][22][23][24][25][26] rely on complicated nanofabrication techniques, some of which might be very time consuming and expensive. Even so, they fail to meet the mentioned requirements all at once.…”

Section: Introductionmentioning

confidence: 99%

Protein patterning by a DNA origami framework

et al. 2016

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A spatial arrangement of proteins provides structural and functional advantages in vast technological applications as well as fundamental research. Most protein patterning procedures employ complicated, time consuming and very costly nanofabrication techniques. As an alternative route, we developed a fully biomolecular self-assembly method using DNA Origami Frames (DOF) as a template for both small and large scale protein patterning. We employed a triangular DOF (tDOF) to arrange the Bovine Serum Albumin (BSA) protein. Our in situ protein patterning strategy provides a novel, fully organic platform using a fast and low-cost surface approach with possible utilization in fundamental science and technological applications.

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Enhanced protein adsorption and patterning on nanostructured latex-coated paper

Cited by 14 publications

References 85 publications

Electro-Optical Gas Sensor Consisting of Nanostructured Paper Coating and an Ultrathin Sensing Element

Electro-Optical Gas Sensor Consisting of Nanostructured Paper Coating and an Ultrathin Sensing Element

Tailored Approaches in Drug Development and Diagnostics: From Molecular Design to Biological Model Systems

Protein patterning by a DNA origami framework

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