2008
DOI: 10.1016/j.apsusc.2008.06.073
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Enhanced cell affinity of poly(l-lactide) film by immobilizing phosphonized chitosan

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Cited by 6 publications
(3 citation statements)
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“…Polylactic acid (PLLA), as one of the most widely used biodegradable polymers, has a variety of biomedical and pharmaceutical applications. However, the application of the PLLA is limited due to the high crystallinity, the hydrophobicity and the absence of functional groups that can be reacted with biologically active moieties [7][8][9].…”
Section: Introductionmentioning
confidence: 99%
“…Polylactic acid (PLLA), as one of the most widely used biodegradable polymers, has a variety of biomedical and pharmaceutical applications. However, the application of the PLLA is limited due to the high crystallinity, the hydrophobicity and the absence of functional groups that can be reacted with biologically active moieties [7][8][9].…”
Section: Introductionmentioning
confidence: 99%
“…PLLA has excellent mechanical properties and can be slowly broken down into nontoxic metabolites. However, its applications have been somewhat limited because of difficulties in controlling the hydrolysis rate, poor hydrophilicity, and high rigidity and crystallinity [ 10 12 ]. Poly(ε-caprolactone) (PCL) is relatively nontoxic, biocompatibility, and possesses sufficient mechanical strength and thermal stability for scaffolding applications.…”
Section: Introductionmentioning
confidence: 99%
“…PLLA is one of the most widely used biodegradable polymers, with a variety of biomedical and pharmaceutical applications. However, the application of the PLLA is limited due to the high crystallinity, the hydrophobicity and the absence of functional groups that can be reacted with biologically active moieties [3][4][5]. Moreover, its acidic degradation by-products could lead to pH decrease in the vicinity of the implants.…”
Section: Introductionmentioning
confidence: 99%