“…They also produce chemokines, including MCP-1/CCL2, MIP-1a/CCL3, MIP-1b/CCL4, RANTES/CCL5, TARC/ CCL17, MIP-3a/CCL20, MDC/CCL22, eotaxin-3/CCL26, CTACK/ CCL27, Gro-a/CXCL1, Mig/CXCL9, IP-10/CXCL10, I-TAC/CXCL11, CXCL16, and fractalkine/CX3CL1 [75,[92][93][94][95][96][97][98][99][100]. These keratinocytederived cytokines and chemokines regulate the inflammatory and immune responses of resident Langerhans cells, dermal fibroblasts, and endothelial cells, as well as infiltrating cells.…”