Enhanced astaxanthin accumulation in Haematococcus pluvialis using high carbon dioxide concentration and light illumination

Christian, David; Zhang, Jun; Sawdon, Alicia J.; Peng, Ching An

doi:10.1016/j.biortech.2018.02.074

Cited by 87 publications

(35 citation statements)

References 17 publications

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“…Total carotenoid (4.57 mg/g dry weight) was produced in a stirred tank PBR scaled from 2 to 10 L at a constant volumetric power consumption (P/V) [ 60 ]. Christian et al 2018 [ 61 ] observed ~3 fold higher astaxanthin yield than this study during cultivation at laboratory scale in 50 mL flask with working volume of 30 mL at 16,200 lux (220 µmol/photons/s/m 2 ) and aeration flow rate of ~7 mL/min, and with an energy input 6.5 fold higher than the present work. In this study, 5.21 ± 0.26 and 19.62 ± 0.98 mg/g of total carotenoids and FAs were detected, respectively.…”

Section: Discussioncontrasting

confidence: 49%

An Integrated Strategy for Nutraceuticals from Haematoccus pluvialis: From Cultivation to Extraction

et al. 2020

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The aim of this study was to develop an effective integrated cultivation system for Haematococcus pluvialis as a source of bioactive compounds such as astaxanthin, lutein, proteins, and fatty acids (FAs). The Chlorophyta H. pluvialis was cultivated in a vertical bubble column photobioreactor (VBC-PBR) under batch mode, allowing switching from green to red phase for astaxanthin induction. The combined effect of light intensity and nutrients on bioactive compound formation was investigated. Results showed that growth under lower nutrients availability and light intensity led to a higher concentration of biomass. Growth under high light intensity with an appropriate concentration of nitrate, sulfate, phosphate and magnesium led to ~85% and ~58% higher production of total carotenoids and fatty acids, respectively. Under high stress conditions, ~90% nitrate and phosphate consumption were observed.

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Section: Discussioncontrasting

confidence: 49%

An Integrated Strategy for Nutraceuticals from Haematoccus pluvialis: From Cultivation to Extraction

et al. 2020

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“…Scenedesmus almeriensis is recognized as a rich source of lutein, containing up to 4.5 mg/g (dry weight), when grown in outdoor culture conditions (Del Campo et al, 2007); moreover, lutein content can be increased by manipulating growth conditions, such as light intensity and temperature, till to 5.4 mg/g (dry weight) (Sánchez et al, 2008b). Christian et al (2018) repot that the astaxanthin content of Haematococcus pluvialis using high concentrations of CO 2 (15%v/v) as the carbon source can achieve the value of about 36 mg/g (dry weight). Cheng et al (2016) observed the highest biomass (0.65 g/L) and astaxanthin (45 mg/L) concentrations in Haematococcus pluvialis grown in 6% CO 2 .…”

Section: Introductionmentioning

confidence: 99%

Enhancing Biomass and Lutein Production From Scenedesmus almeriensis: Effect of Carbon Dioxide Concentration and Culture Medium Reuse

et al. 2020

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The main purpose of this study is to investigate the effects of operative parameters and bioprocess strategies on the photo-autotrophic cultivation of the microalgae Scenedesmus almeriensis for lutein production. S. almeriensis was cultivated in a vertical bubble column photobioreactor (VBC-PBR) in batch mode and the bioactive compounds were extracted by accelerated solvent extraction with ethanol at 67 • C and 10 MPa. The cultivation with a volume fraction of CO 2 in the range 0-3.0%v/v showed that the highest biomass and lutein concentrations-3.7 g/L and 5.71 mg/g, respectively-were measured at the highest CO 2 concentration and using fresh growth medium. Recycling the cultivation medium from harvested microalgae resulted in decreased biomass and lutein content. The nutrient chemical composition analysis showed the highest consumption rates for nitrogen and phosphorus, with values higher than 80%, while sulfate and chloride were less consumed.

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“…The introduction of CO 2 or organic sources of carbon, such as acetate, altered the C/N balance, creating a relative nitrogen deficiency which stimulated astaxanthin accumulation and cyst formation [218,219]. In photo-autotrophic cultures, the addition of CO 2 at a level comprised between 1.5% and 5% in air has a beneficial effect on vegetative growth [217,218,220] and astaxanthin accumulation under stress, which resulted in a higher overall astaxanthin productivity. However, an excess of CO 2 up to 10% or 20% in air was deteriorative for growth, photosynthesis, and carbon assimilation [220].…”

Section: Nutrients Availabilitymentioning

confidence: 99%

Novel Insights into the Biotechnological Production of Haematococcus pluvialis-Derived Astaxanthin: Advances and Key Challenges to Allow Its Industrial Use as Novel Food Ingredient

Jannel

Caro

Bermudes³

et al. 2020

JMSE

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Astaxanthin shows many biological activities. It has acquired a high economic potential and its current market is dominated by its synthetic form. However, due to the increase of the health and environmental concerns from consumers, natural forms are now preferred for human consumption. Haematococcus pluvialis is artificially cultured at an industrial scale to produce astaxanthin used as a dietary supplement. However, due to the high cost of its cultivation and its relatively low biomass and pigment productivities, the astaxanthin extracted from this microalga remains expensive and this has probably the consequence of slowing down its economic development in the lower added-value market such as food ingredient. In this review, we first aim to provide an overview of the chemical and biochemical properties of astaxanthin, as well as of its natural sources. We discuss its bioavailability, metabolism, and biological activities. We present a state-of-the-art of the biology and physiology of H. pluvialis, and highlight novel insights into the biotechnological processes which allow optimizing the biomass and astaxanthin productivities. We are trying to identify some lines of research that would improve the industrial sustainability and economic viability of this bio-production and to broaden the commercial potential of astaxanthin produced from H. pluvialis.

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Enhanced astaxanthin accumulation in Haematococcus pluvialis using high carbon dioxide concentration and light illumination

Cited by 87 publications

References 17 publications

An Integrated Strategy for Nutraceuticals from Haematoccus pluvialis: From Cultivation to Extraction

An Integrated Strategy for Nutraceuticals from Haematoccus pluvialis: From Cultivation to Extraction

Enhancing Biomass and Lutein Production From Scenedesmus almeriensis: Effect of Carbon Dioxide Concentration and Culture Medium Reuse

Novel Insights into the Biotechnological Production of Haematococcus pluvialis-Derived Astaxanthin: Advances and Key Challenges to Allow Its Industrial Use as Novel Food Ingredient

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