Enhanced antioxidant capacity and antimicrobial activity of tannic acid by thermal processing

Kim, T.J.; Silva, J.L.; Kim, M.K.; Jung, Yean-Sung

doi:10.1016/j.foodchem.2009.05.060

Cited by 150 publications

(120 citation statements)

References 27 publications

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“…Here, a new generation of p(TA) particles modified with quaternary ammonium salt and sulfonic acids are generated by using CHPACl and CSA as modifying agents via a simple post modification procedure to generate some positive and more negative charges on the p(TA) particle network. The new functional groups together with the innate properties of TA provide additional value for multiple biological functions, using antioxidant [20,21], antimicrobial [5], anti-inflammatory [22], and antitumor characteristics [23,24]. Therefore, we also investigate the effect of chemical modifications of p(TA) on the antioxidant and antimicrobial properties of the particles.…”

Section: Introductionmentioning

confidence: 99%

Modified biofunctional p(tannic acid) microgels and their antimicrobial activity

Sagbas

Aktaş

Şahiner

2015

Applied Surface Science

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Section: Introductionmentioning

confidence: 99%

Modified biofunctional p(tannic acid) microgels and their antimicrobial activity

Sagbas

Aktaş

Şahiner

2015

Applied Surface Science

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“…There are several reports on the use of tannins in treating various diseases in humans, including snake bites, diarrhoea, gastric ulcers and wounds (Pereira et al, 2001;Palombo, 2006). Hydrolysable tannins and derivatives have shown bacteriostatic and bactericidal activities (Kim et al, 2010). The antimicrobial properties of tannins could be associated with the hydrolysis of ester linkage between gallic acid, and multiple esters with D-glucose, which affects the biosynthesis steps in the syntheses of cell membrane and cell walls, causing a decrease in cell volume, by the disjunction of cell membrane from the cell wall (Cowan, 1999;Suraya & Darah, 2002).…”

Section: Discussionmentioning

confidence: 99%

“…Family Asteraceae comprises about 1100 genera and 25000 species, and Vernonia is considered the family's most representative genus, including about 1000 species with high pharmacological potential (Zomlefer, 1994;Lorenzi & Matos, 2008). The genus Vernonia, native to Brazil, is found in some regions from the states of Bahia, Minas Gerais and Santa Catarina, and is typically presented in the form of small shrubs to small trees.…”

Section: Introductionmentioning

confidence: 99%

“…Vernonia polyanthes is commonly known in Brazil as assa-peixe, chamarrita, cambará-guaçu, white-cambará and white assa-peixe, and presents some synonymies as Vernonia patens Less, Vernonanthura rigiophylla, Vernonanthura phosphoric, Eupatorium polyanthes Spreg (Lorenzi & Matos, 2008). V. polyanthes leaves have been studied and their pharmacological properties such as antinociceptive and anti-inflammatory (Temponi et al, 2012), antihypertensive and diuretic (Silveira et al, 2003a;Silveira et al, 2003b), antiulcerogenic (Barbastefano et al, 2007), antifungal and leishmanicidal (Braga et al, 2007), mutagenic and antimycobacterial (Oliveira et al, 2007;Jorgetto et al, 2011), have been established.…”

Section: Introductionmentioning

confidence: 99%

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Antimicrobial activity of crude extracts and fractions of Vernonia polyanthes Less (assa-peixe) flowers

Waltrich

Hoscheid

Prochnau

2015

Rev. bras. plantas med.

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Antimicrobial activity of crude extracts and fractions of Vernonia polyanthes Less (assa-peixe) flowers. Vernonia polyanthes, known as "assa-peixe", is a plant native to Brazil, and the decoction or infusion of its flowers, roots and leaves are used in folk medicine, being considered sources of diuretic, balsamic, anti-rheumatic substances, and are used in cases of bronchitis and persistent cough. The aim of the study was to evaluate the antimicrobial activity of the extract/fractions obtained by methanol maceration and infusion of V. polyanthes flower, also including qualitative identification of flower compounds, through phytochemical evaluation, using colorimetric tests. Identification tests for the presence of anthraquinones, tannins, flavonoids, saponins and alkaloids were performed. Microbiological evaluation was made through agar diffusion assay, using Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa as test organisms. From the performed colorimetric tests it was possible to verify the presence of tannins and flavonoids in both extracts. Alkaloids were also observed in the macerated extract. The ethyl acetate fraction from the agar diffusion assay, from both extracts, presented microbial activity over Staphylococcus aureus. It was possible to qualitatively identify the floral compounds, and to show the differences between extraction methods, being methanol considered the best solvent to the extraction.Keywords: Assa-peixe; Cambará; Medicinal plants; Phytochemical profile. RESUMO: Atividade antimicrobiana de extrato bruto e de frações de flores de Vernonia polyanthes Less (assa-peixe).Vernonia polyanthes, conhecida como assa-peixe, é planta nativa do Brasil e suas flores, raízes e folhas, em decocção ou infusão, são empregadas na medicina caseira como diuréticas, balsâmicas, e anti-reumáticas, usadas nos casos de bronquite e tosse persistente. O objetivo do trabalho foi avaliar a atividade antimicrobiana do extrato/ frações obtidos por maceração em metanol e infusão de flores de V. polyanthes, incluindo também a identificação qualitativa dos compostos presentes nas flores, através da avaliação fitoquímica, empregando testes colorimétricos. Foram realizados testes para identificação de antraquinonas, taninos, flavonóides, saponinas e alcalóides. A avaliação microbiológica foi realizada por meio de ensaio de difusão em ágar, empregando Escherichia coli, Staphylococcus aureus e Pseudomonas aeruginosa. A partir dos testes colorimétricos foi possível verificar a presença de taninos e flavonóides em ambos os extratos. Ainda, no extrato macerado, foi observada a presença de alcalóides. No ensaio de difusão em ágar, a fração acetato de etila de ambos os extratos, apresentou atividade antimicrobiana sobre Staphylococcus aureus. Foi possível identificar qualitativamente os compostos da flor, demonstrando diferença entre as técnicas de extração, sendo que o metanol resultou em melhor poder extrativo.

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“…It has been suggested that starch digestion was slowed in a dose-dependent manner, and that foods/drinks, like wine, containing comparatively high levels of tannic acid, could moderate postprandial levels of blood glucose and corresponding insulin. The loss or decrease of the ability to inhibit α-amylase in vivo may occur (Kim, Silva, Kim, & Jung, 2010). This may be because: (i) tannic acid might be oxidized by oxygen and oxygen-derived radicals in the stomach; (ii) tannic acid could interact or bind with proteins present in foods and stomach digesta before reaching the small intestine where starch is hydrolyzed by pancreatic α-amylase (Martinez & Moyano, 2003).…”

Section: Phenolic Acidsmentioning

confidence: 99%

Studying the interactions between tea polyphenols and α-amylase

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Dixon, Cornish-Bowden and Lineweaver-Burk plot analyses were applied to study the detailed kinetics of inhibition of porcine pancreatic α-amylase (PPA) by tea polyphenols.Fluorescence quenching (FQ), differential scanning calorimetry (DSC) and isothermal titration calorimetry (ITC) were combined with the kinetics of inhibition to elucidate the mechanism of binding interactions of tea polyphenols and PPA. Then, the reciprocal of competitive inhibition constant (1/K ic ), fluorescence quenching constant (K FQ ) and binding constant (K itc ) obtained from these measurements were compared and correlated to analyse the relations between PPA inhibition and binding behaviour. The role of the galloyl moiety in binding of catechins and theaflavins with PPA was highlighted as well. In addition, the effects of three soluble polysaccharides (citrus pectin (CP), wheat arabinoxylan (WAX) and oat β-glucan (OBG)) on the inhibition of PPA by tea polyphenols were studied through PPA inhibition, IC 50 value, inhibition kinetics and fluorescence quenching methods. Furthermore, the effects of tea polyphenols on binding of PPA with normal maize starch granules were studied in terms of binding ratio, dissociation constant (K d ) and binding rate. Then, the association constant (1/K d ), 1/K ic and K FQ of tea polyphenols were correlated to analyse the effects of PPA inhibition on the binding of the enzyme with starch.The results show that green, oolong and black tea extracts, epigallocatechin gallate, theaflavin-3, 3'-digallate and tannic acid were competitive inhibitors of PPA, whereas epicatechin gallate, theaflavin-3'-gallate and theaflavin were mixed-type inhibitors with both competitive and uncompetitive inhibitory characteristics. Only catechins with a galloyl substituent at the 3-position showed measurable inhibition. K ic values were lower for theaflavins than catechins, with the lowest value for theaflavin-3, 3'-digallate. The lower K ic than the uncompetitive inhibition constant for the mixed-type inhibitors suggests that they bind more tightly with free PPA than with the PPA-starch complex. A 3 and/or 3'-galloyl moiety in catechin and theaflavin structures was consistently found to increase inhibition of PPA through enhanced association with the enzyme active site. A higher quenching effect of polyphenols corresponded to a stronger inhibitory activity against PPA. The red-shift of maximum emission wavelength of PPA bound with some polyphenols indicated a potential IV

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Enhanced antioxidant capacity and antimicrobial activity of tannic acid by thermal processing

Cited by 150 publications

References 27 publications

Modified biofunctional p(tannic acid) microgels and their antimicrobial activity

Modified biofunctional p(tannic acid) microgels and their antimicrobial activity

Antimicrobial activity of crude extracts and fractions of Vernonia polyanthes Less (assa-peixe) flowers

Studying the interactions between tea polyphenols and α-amylase

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