Enhanced antimicrobial activity of essential oil components immobilized on silica particles

Ruiz-Rico, María; Pérez‐Esteve, Édgar; Bernardos, Andrea; Sancenón, Félix; Martínez‐Máñez, Ramón; Marcos, M. Dolores; Baviera, José Manuel Barat

doi:10.1016/j.foodchem.2017.04.118

Cited by 71 publications

(43 citation statements)

References 36 publications

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“…Mesoporous silica particles exhibit unique features, such as high stability, biocompatibility, non-apparent toxicity, large load capacity and the possibility of including gate-like scaffoldings on the external surface [13]. In addition, these materials have been proved to be an effective method for controlling the release rate of active compounds [14][15][16][17][18]. The use of mesoporous silica particles presents a suitable approach to avoid some problems such as complex mass transport phenomena, interaction with food constituents or functional modifications due to physical and chemical food processes.…”

Section: Introductionmentioning

confidence: 99%

Biodegradable Poly(ε-Caprolactone) Active Films Loaded with MSU-X Mesoporous Silica for the Release of α-Tocopherol

et al. 2020

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In this study, new active PCL (poly(ε-caprolactone)) films containing α-tocopherol (TOC) and MSU-X mesoporous silica were prepared by melt blending. The studied additives were directly incorporated into the polymer matrix or by impregnating TOC into MSU-X silica (PCL-IMP). Thermal, optical, oxygen and water barrier properties as well as oxidation onset parameters, were studied. Films containing MSU-X and/or TOC showed a significant increase in oxidative onset temperature (OOT) and oxidative induction time (OIT), improving thermal stability against materials oxidation by the addition of mesoporous silica and TOC into the polymer matrix. In addition, the effect of MSU-X addition on the migration behaviour of α-tocopherol from active films was investigated at 40 °C using 50% (v/v) ethanol as fatty food simulant, showing PCL-IMP films the lower release content and diffusion coefficient (3.5 × 10−15 cm2 s−1). Moreover, radical scavenging (DPPH and ABTS) and antibacterial activity against E. coli and S. aureus were favoured by the release of α-tocopherol in the developed films. The obtained results have demonstrated the potential of the new PCL-based active formulations for TOC controlled release in antioxidant and antibacterial food packaging applications.

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Section: Introductionmentioning

confidence: 99%

Biodegradable Poly(ε-Caprolactone) Active Films Loaded with MSU-X Mesoporous Silica for the Release of α-Tocopherol

et al. 2020

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“…In other words, the nanoembedding process did not change antibacterial activity of PFEO. Moreover, PFEO even displayed greater bactericidal activity after encapsulation …”

Section: Resultsmentioning

confidence: 99%

“…Moreover, PFEO even displayed greater bactericidal activity after encapsulation. 42 The MBC of EONs against S. aureus culturing for 48 h (20 mg mL −1 ) was also lower than that for 24 h incubation (22.5 mg mL −1 ). In fact, the same trend can also be observed in the L. monocytogenes group (Fig.…”

Section: Bactericidal Activity Of Eonsmentioning

confidence: 91%

Pepper fragrant essential oil (PFEO) and functionalized MCM‐41 nanoparticles: formation, characterization, and bactericidal activity

Jin

Teng

et al. 2019

J Sci Food Agric

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BACKGROUND It is well known that plant essential oils have good antimicrobial activity. However, their strong volatility and intense odor limit their application. Mesoporous silica (MCM‐41), a non‐toxic mesoporous material with excellent loading capability, is a promising delivery system for different types of food ingredients in the food industry. RESULTS In this study, we first performed component analysis of pepper fragrant essential oil (PFEO) by gas chromatography – mass spectrometry (GC–MS), then the MCM‐41 host was prepared, and the essential oil functionalized nanoparticles (EONs) were formed by embedding PFEO into mesoporous silica particles. Further analysis indicated that the particle size and zeta potential of EONs were 717 ± 13.38 nm and − 43.90 ± 0.67 mV, respectively. Transmission electron microscopy (TEM) images showed that EONs had an inerratic morphology and stable structure. The bactericidal activities of PFEO and EONs against Escherichia coli (E. coli), Salmonella enterica (S. enterica), Staphylococcus aureus (S. aureus) and Listeria monocytogenes (L. monocytogenes) were subsequently tested using the twofold dilution method. Results indicated that, after 48 h incubation, minimum bactericidal concentrations (MBC) of EONs used against gram‐negative bacteria were decreased to a greater degree than those of PFEO, suggesting that nanoencapsulation by MCM‐41 can improve antimicrobial activity. Atomic force microscopy (AFM) observation also confirmed that EONs showed a notable inhibitory effect against E. coli by disrupting cell membrane structure. CONCLUSION Pepper fragrant essential oil nanoencapsulation could be a very promising organic delivery system in food industry for antimicrobial activity enhancement. © 2019 Society of Chemical Industry

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“…The essential oil components carvacrol, eugenol, thymol, and vanillin were covalently anchored onto three different MS supports (fumed silica, amorphous silica, and MCM‐41) and the antibacterial properties of the prepared materials tested against E. coli and L. innocua . For the covalent immobilization of carvacrol, eugenol, and thymol onto the inorganic siliceous supports, the aromatic compounds were functionalized with aldehyde groups using well‐known formylation protocols.…”

Section: Ms In Antibacterial Applicationsmentioning

confidence: 99%

Mesoporous Silica‐Based Materials with Bactericidal Properties

Bernardos

Piacenza

Sancenón

et al. 2019

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Bacterial infections are the main cause of chronic infections and even mortality. In fact, due to extensive use of antibiotics and, then, emergence of antibiotic resistance, treatment of such infections by conventional antibiotics has become a major concern worldwide. One of the promising strategies to treat infection diseases is the use of nanomaterials. Among them, mesoporous silica materials (MSMs) have attracted burgeoning attention due to high surface area, tunable pore/particle size, and easy surface functionalization. This review discusses how one can exploit capacities of MSMs to design and fabricate multifunctional/controllable drug delivery systems (DDSs) to combat bacterial infections. At first, the emergency of bacterial and biofilm resistance toward conventional antimicrobials is described and then how nanoparticles exert their toxic effects upon pathogenic cells is discussed. Next, the main aspects of MSMs (e.g., physicochemical properties, multifunctionality, and biosafety) which one should consider in the design of MSM‐based DDSs against bacterial infections are introduced. Finally, a comprehensive analysis of all the papers published dealing with the use of MSMs for delivery of antibacterial chemicals (antimicrobial agents functionalized/adsorbed on mesoporous silica (MS), MS‐loaded with antimicrobial agents, gated MS‐loaded with antimicrobial agents, MS with metal‐based nanoparticles, and MS‐loaded with metal ions) is provided.

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Enhanced antimicrobial activity of essential oil components immobilized on silica particles

Cited by 71 publications

References 36 publications

Biodegradable Poly(ε-Caprolactone) Active Films Loaded with MSU-X Mesoporous Silica for the Release of α-Tocopherol

Biodegradable Poly(ε-Caprolactone) Active Films Loaded with MSU-X Mesoporous Silica for the Release of α-Tocopherol

Pepper fragrant essential oil (PFEO) and functionalized MCM‐41 nanoparticles: formation, characterization, and bactericidal activity

Mesoporous Silica‐Based Materials with Bactericidal Properties

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