Enhanced anti-biofilm activity of the minocycline-and-gallium-nitrate using niosome wrapping against Acinetobacter baumannii in C57/BL6 mouse pneumonia model

Composition, preparation methods, and applications of nanoniosomes as codelivery systems: a review of emerging therapies with emphasis on cancer

“…Shamkani et al loaded minocycline and gallium nitrate into niosomes and validated the anti-biofilm activity toward Acinetobacter baumannii . 197 In order to form an aqueous polymer solution, polyethylene glycol and polyvinylpyrrolidone were incorporated into the as-prepared niosomal formulation. Entrapment efficiencies for gallium nitrate and minocycline niosomal formulations were 42.5 and 81.5%, respectively.…”

Gallium-based metal–organic frameworks loaded with antimicrobial peptides for synergistic killing of drug-resistant bacteria

“…[29][30][31] In particular, as an FDA approved drug, the antibacterial mechanism, effect, and application of gallium nitrate have been extensively studied. [32][33][34][35] Although there have been many studies on antibacterial MOFs, few studies on gallium-based MOFs have been reported. 36 In this study, we synthesized a Ga-based MOF as a platform to load melittin (MEL), a typical AMP stemmed from honeybee (Apis mellifera) venom, and investigated its antibacterial activity against clinical isolated methicillin-resistant Staphylococcus aureus (MRSA) and Escherichia coli (E. coli).…”