Gallium-based metal–organic frameworks loaded with antimicrobial peptides for synergistic killing of drug-resistant bacteria

Abstract

Increased antibiotic resistance has made bacterial infections a global concern, which requires novel non-antibiotic-dependent antibacterial strategies to address the menace. Antimicrobial peptides (AMPs) are a promising antibiotic alternative, whose antibacterial...

Near-infrared light-actuated on-demand botanicals release and hyperthermia by an antibiotic-free polysaccharide-based hydrogel dressing for the synergistic treatment of wound infections

“…7 On the other hand, the massive use of antibiotics and unregulated treatment will inevitably lead to the problem of extensive drug resistance and multi-drug resistance of bacterial strains, 8 which poses a challenge to the treatment of infectious diseases. 9–11 Therefore, there is an urgent need to find a novel class of antibiotic-free methods for combating bacterial infections in wounds.…”