Engineered Bioactive Polymeric Surfaces by Radiation Induced Graft Copolymerization: Strategies and Applications

Nasef, Mohamed Mahmoud; Gupta, Bhuvanesh; Shameli, Kamyar; Verma, Chetna; Ali, Rusmidah; Ting, Teo Ming

doi:10.3390/polym13183102

Cited by 22 publications

(18 citation statements)

References 186 publications

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“…Although, the water drop contact angle showed that the surface of the PP-g-MMA was wet consistently as the contact angle decreased while the grafting degree increased. Overall, the swelling and contact angle results suggest an increase in the surface energy of the grafted films, being that suitable to use in drug release systems [34].…”

Section: Discussionmentioning

confidence: 87%

Polypropylene Graft Poly(Methyl Methacrylate) Graft Poly(N-Vinylimidazole) as a Smart Material for pH-Controlled Drug Delivery

López‐Saucedo¹,

López-Barriguete²,

Flores-Rojas³

et al. 2021

Preprint

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Surface modification of polypropylene (PP) films is achieved using gamma-irradiation-induced grafting to proffer with antimicrobial activity. The copolymer was obtained through a versatile two-step route; pristine PP is exposed to gamma rays and grafted using methyl methacrylate (MMA), then N-vinylimidazole (NVI) is grafted onto the copolymer PP-g-MMA by simultaneous irradiation. The characterization included Fourier-Transform Infrared Spectroscopy (FTIR), Scanning Electron Microscope (SEM), Thermogravimetric Analysis (TGA), X-ray Photoelectron Spectroscopy (XPS), and physicochemical analysis of swelling and contact angle. The copolymer (PP-g-MMA)-g-NVI was loaded with vancomycin, and the drug released was quantified by UV-vis spectrophotometry at different pH. The surface of (PP-g-MMA)-g-NVI exhibited pH-responsiveness and moderate hydrophilicity, suitable properties for controlled drug release.

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Section: Discussionmentioning

confidence: 87%

Polypropylene Graft Poly(Methyl Methacrylate) Graft Poly(N-Vinylimidazole) as a Smart Material for pH-Controlled Drug Delivery

López‐Saucedo¹,

López-Barriguete²,

Flores-Rojas³

et al. 2021

Preprint

View full text Add to dashboard Cite

show abstract

“…The water drop contact angle showed that the surface of the PP- g -MMA was wet consistently as the contact angle decreased while the grafting degree increased. Overall, the swelling and contact angle results suggest an increase in the surface energy of the grafted films and are suitable to use in drug release systems [ 38 ].…”

Section: Discussionmentioning

confidence: 99%

Polypropylene Graft Poly(methyl methacrylate) Graft Poly(N-vinylimidazole) as a Smart Material for pH-Controlled Drug Delivery

López‐Saucedo¹,

López-Barriguete²,

Flores-Rojas³

et al. 2021

IJMS

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Surface modification of polypropylene (PP) films was achieved using gamma-irradiation-induced grafting to provide an adequate surface capable of carrying glycopeptide antibiotics. The copolymer was obtained following a versatile two-step route; pristine PP was exposed to gamma rays and grafted with methyl methacrylate (MMA), and afterward, the film was grafted with N-vinylimidazole (NVI) by simultaneous irradiation. Characterization included Fourier transform infrared spectroscopy (FTIR), scanning electron microscope (SEM), thermogravimetric analysis (TGA), X-ray photoelectron spectroscopy (XPS), and physicochemical analysis of swelling and contact angle. The new material (PP-g-MMA)-g-NVI was loaded with vancomycin to quantify the release by UV-vis spectrophotometry at different pH. The surface of (PP-g-MMA)-g-NVI exhibited pH-responsiveness and moderate hydrophilicity, which are suitable properties for controlled drug release.

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“…After 24 hours . Centrifugation the solution at 15000 rpm for 15 min, and then filtering by use filter paper (20) . Pour the solution into a dish and let it .…”

Section: Preparation Of Silver Nanoparticlesmentioning

confidence: 99%

Comparison between effective compounds between peel and seeds of Capparis Spinosa

Gassad

Fajer

2022

ijhs

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Capparis Spinosa is considered among the most important commercial crops in the Caper family, Where the height of the Capparis spinosa tree ranges from 1 to2m and its roots reach 40cm the plant is ever green in a green blue color, and the branches creeping and semi-break easy to break, the leaves are thick circular or oval. Capparis Spinoza has been selected because of its medical advantages where it uses a painkiller, treatment of intestinal bacterial infection and uses its leaves as food spices. These effective compound were detected using GC-MS, which is considered as strong antioxidant, and when the plant was extracted with the GC-MS device, the peel appeared to be more effective than the seed,because they contained high effective compounds, where the peel included the highest percentage in dl- alpha- Tocopherol succinate,which reached about 29.384 is one of the strong antioxidants that inhibit free radicals and protect cells from oxidative stress and is considered the most active of the compounds tocopherol in relation to seeds, it included 28.901 E-11-Tetradecenoic acid and n-Hexadecanoic acid ,phytol ,the capparis spinosa plant is rich in phenolic compounds due to the presence of many flavonoid compounds in different parts and in high quantities.

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Engineered Bioactive Polymeric Surfaces by Radiation Induced Graft Copolymerization: Strategies and Applications

Cited by 22 publications

References 186 publications

Polypropylene Graft Poly(Methyl Methacrylate) Graft Poly(N-Vinylimidazole) as a Smart Material for pH-Controlled Drug Delivery

Polypropylene Graft Poly(Methyl Methacrylate) Graft Poly(N-Vinylimidazole) as a Smart Material for pH-Controlled Drug Delivery

Polypropylene Graft Poly(methyl methacrylate) Graft Poly(N-vinylimidazole) as a Smart Material for pH-Controlled Drug Delivery

Comparison between effective compounds between peel and seeds of Capparis Spinosa

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