2019
DOI: 10.20538/1682-0363-2019-2-287-289
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Endotypes of allergic rhinitis and asthma accompanying food allergy

Abstract: 61 people suffering from persistent allergic rhinitis and asthma accompanying food allergies were studied using case histories, the NHANES questionnaire, polyspecific serum levels, allergen-specific IgE, IL4, IFNg and IL10 assays, and allergy skin tests. Four different endotypes have been identified, including entopic, which can be the basis for new approaches to the diagnosis and treatment of allergic rhinitis and asthma.

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Cited by 7 publications
(4 citation statements)
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References 12 publications
(11 reference statements)
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“…Different forms of allergies affect approximately one-third of the world's population in Europe, and the rates are growing. There is a tendency for several allergic diseases to be present in the same individual simultaneously [42]. In the epidemiological study, allergic rhinitis occurred in 46.4%, asthma was in 11.2 %, and allergic multimorbidity was diagnosed in 9.7% compared with a single allergic disease in 43.4%.…”
Section: Co-influence Of Respiratory and Food Allergiesmentioning
confidence: 99%
“…Different forms of allergies affect approximately one-third of the world's population in Europe, and the rates are growing. There is a tendency for several allergic diseases to be present in the same individual simultaneously [42]. In the epidemiological study, allergic rhinitis occurred in 46.4%, asthma was in 11.2 %, and allergic multimorbidity was diagnosed in 9.7% compared with a single allergic disease in 43.4%.…”
Section: Co-influence Of Respiratory and Food Allergiesmentioning
confidence: 99%
“…Таким образом, дифференциальными критериями в этом кластерном исследовании оказались пол, присутствие астмы, степень тяжести и возраст начала болезни. Несколько других клинических фенотипов и эндотипов были в последующем исследованы в разных работах [40], однако именно эндотипирование и определение подтверждающих диагноз аллергического ринита биомаркеров показали более существенное значение для ведения пациентов и персонализированной терапии [41,42].…”
Section: Aллергический ринит: фенотипы эндотипы и биологические маркерыunclassified
“…Расстройства путей коммуникации двух систем могут быть основой патологических состояний, которые когда-то рассматривались как изолированные болезни отдельных органов [1]. Участие нейромолекул в патогенезе аллергического воспаления, включая эндотипы аллергического ринита [2], сделало эту проблему очень актуальной.…”
Section: Introductionunclassified