Endothelial changes in phakic eyes with anterior chamber intraocular lenses to correct high myopia

Abstract

Endothelial cell loss during the first year was similar in eyes with Worst-Fechner and Baikoff ZB5M lenses; however, at 2 years after surgery, endothelial cell loss was higher in eyes with Worst-Fechner lenses than it was in eyes with Baikoff ZB5M lenses.

Correction of high myopia with different phakic anterior chamber intraocular lenses: ICARE angle-supported lens and Verisyse iris-claw lens

“…In our Verisyse group, endothelial cell loss was lower than in the studies of Van der Pol et al [35], Menezo, Avino et al [18], and PerezSantonja et al [26], who, at 1 year after the procedure, noted a 8.9%, 7.9%, and 13% reduction, respectively. There are also reports on very low endothelial cell loss, e.g.…”

“…Endothelial cell density decrease may undoubtedly result from perioperative trauma [2,14,35], transient contact between the implanted lens and inner corneal surface, mainly when patients rub their eyes [26], and sublinical inflammatory condition in response to a foreign body within the anterior chamber [7,26].…”

Iris-fixated toric phakic intraocular lens: Three-year follow-up

“…Risk factors for progressive endothelial cell loss are age, flat ACD, and a thicker IOL optic. 18 Menezo et al 19 report a mean endothelial loss of 6.6 % at 1 year, 9.2% at 2 years, and 11.7% at 3 years. Pérez-Santonja et al 18 describe a 13% endothelial cell loss at 1 year and 17.6% 2 years after implantation.…”

Laser in situ Keratomileusis following the Implantation of Iris-Fixated Phakic Intraocular Lenses

“…This increased rate of ECL might be traceable to a shallower anterior-chamber depth on the part of hyperopic patients. An overall comparable loss of endothelial cells also appears to necessitate implantation of an iris-fixated pIOL alone (3.9–13%) [9,21,22,23]. Therefore, a double-pronged surgical procedure does not appear to us to be necessary.…”