The implantation of both anterior chamber phakic intraocular lenses to correct high myopia resulted in a stable and predictable refractive outcome. Efficacy and safety of surgery for both implanted lens models are very high.
The implantation of tested multifocal intraocular lenses provides good near and distance visual acuity. We did not observe any statistically significant differences between the tested multifocal intraocular lenses with regard to best-corrected distance visual acuity, presence of glare and halo, as well as satisfaction with vision.
A limbal 1.0 mm diameter trephination is made beneath the limbus-based conjunctival flap, a small iridectomy is performed. From the external layers of the trephine button one third of the corneoscleral thickness, in the form of a thin disc, is excised. The scleral disc, a free auto-implant, is dipped into liquid containing MMC with concentration 0.2 mg/ml for 5 minutes, outside the eye. Afterwards the scleral disc soaked with MMC is carefully irrigated with 150 ml of BSS and placed in the external part of the trephine fistula in primary position and stabilized with two interrupted 10-0 nylon sutures. The operation is ended as a typical trabeculectomy. The final success rate in terms of IOP (IOP < 14 mmHg) was 100%, without or with antiglaucoma medication, in both groups, but the number of postoperative complications was significantly lower in group 2. Trephination with free scleral auto-implant plug soaked with MMC may represent a viable alternative to trabeculectomy with MMC; the scleral plug may be taken out of the eye and exposed to antimetabolite outside the eye to minimize toxicity.
BackgroundA growing body of evidence suggests that effective blood pressure reduction may inhibit the progression of microvascular damage in patients with essential arterial hypertension. However, the potential influence of anti-hypertensive drugs on ocular circulation has not been studied sufficiently.PurposeThe aim of our study was to evaluate the effects of anti-hypertensive therapy on blood flow in the central retinal artery in patients with systemic arterial hypertension.Material and methodsTwenty patients with essential arterial hypertension, aged 32–46 years, were examined with Doppler ultrasonography (10 MHz ultrasound probe). Blood flow velocities, pulsatility, and vascular resistance were determined before and 3 hours after systemic application of either bisoprolol 5 mg or cilazapril 2.5 mg.ResultsAdministered bisoprolol significantly decreased maximum (9.8 ± 0.5 cm/s versus 8.5 ± 0.6 cm/s; P < 0.05) and minimum (2.75 ± 0.19 cm/s versus 1.75 ± 0.27 cm/s; P < 0.02) velocity, increased the Pourcellot's index (0.71 to 0.79; P < 0.05) in central retinal artery. There were no statistically significant changes in central retinal artery blood flow after administration of cilazapril.ConclusionSystemic application of beta-blockers may unfavourably disturb the ocular blood flow.
Purpose: The aim of this study was to observe human corneas after Photorefractive keratectomy (PRK), in vivo, using the Scanning Slit Confocal Microscope ,,Confoscan P4" (Tomey). Material and method: The material consists of 80 corneas of 45 patients where in vivo, non-invasive evaluation of the corneal structures was performed with a confocal microscope. The confocal microscopic examination was performed in cases after excimer laser refractive surgery and analysed together with the type of the procedure (myopia, hyperopia and astigmatism correction), and with the patients age and sex. The results obtained in the right and left eye of each patient after bilateral procedures were compared. The state of the cornea was analysed in relation to follow-up time. Results: The observations consist of the structure of conical epithelium, stromal keratocytes, topography ofnerve fibres, appearance ofBowmans and Descemets membranes and condition of endothelia! cells. Conclusion: The confocal microscope allows non-invasive in vivo observations of the corneal structures and is capable of the evaluation of corneal healing after excimer laser refractive procedures.
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