Endoscopic Treatment of Central Airway Stenosis: Five Years' Experience

Povedano, Andrés Cosano; Cabrera, Luís Muñoz; Povedano, F. J. Cosano; Sánchez, Joaquín; Martínez, N. Pascual; Dueñas, Aguilar

doi:10.1016/s1579-2129(06)60231-0

Cited by 20 publications

(14 citation statements)

References 20 publications

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“…Various prospective and retrospective studies have reported that 33%-53% of all patients with CAO are of nonmalignant etiology. [ 2 4 8 ] PITS remains the most common reported cause of nonmalignant CAO in most studies, including ours. [ 2 4 9 10 ] Compared to most Western literature, we found a high occurrence of posttubercular stenosis among our patients (22.5%), a finding similar to that reported in some previous studies, notably with Asian subjects.…”

Section: Discussionmentioning

confidence: 72%

“…[ 1 ] The quality of life of most patients with significant CAO is seriously impaired by dyspnea, stridor, or respiratory failure. [ 2 ] While surgical resection with reconstruction is the treatment of choice, many patients are inoperable, too unwell, or have significant comorbidities that exclude them from this modality. Interventional therapeutic bronchoscopy procedures such as airway stent insertion, laser, electrocautery, cryotherapy, and argon-plasma coagulation are alternative modalities that may provide immediate benefits.…”

Section: Introductionmentioning

confidence: 99%

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Therapeutic bronchoscopic interventions for nonmalignant central airway obstruction provide rapid and sustained improvement in symptoms and functional status

et al. 2020

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Section: Discussionmentioning

confidence: 72%

Section: Introductionmentioning

confidence: 99%

Therapeutic bronchoscopic interventions for nonmalignant central airway obstruction provide rapid and sustained improvement in symptoms and functional status

et al. 2020

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“…Immediate symptomatic relief and improvement in quality of life is seen in most patients with malignant airway obstruction after stent deployment21 22 23 (fig 7A–C). Similar success has been reported in benign disease, with 39 of 40 patients reporting a symptomatic benefit in one study 24.…”

Section: Discussionmentioning

confidence: 99%

“…Procedural complications are uncommon, but include perforation of the wall of the airway, pneumothorax and malpositioning of the stent at the time of deployment. No deaths related to the procedure have been reported in recent series 17 19 21 23 30 31. Stent-related complications include migration, retention of secretions, infection, occlusion and collapse of lobar bronchi and granulation tissue formation 32 33.…”

Section: Complicationsmentioning

confidence: 99%

Endobronchial stenting in the management of large airway pathology

Ranu

Madden

2009

Postgraduate Medical Journal

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Endobronchial interventions including the deployment of endobronchial stents have a clear role in the management of central airway problems. The use of endobronchial stents has rapidly increased since the first airway stent was developed in the 1960s and with the subsequent manufacture of improved silicone and metallic stents. They provide effective relief for symptoms of intrinsic and extrinsic airway obstruction secondary to a wide range of pathologies including lung cancer, lymphoma, thyroid carcinoma and benign disease such as tracheal strictures and tracheobronchomalacia. Endobronchial stents can also seal defects within the airway including malignant broncho-oesophageal fistulae and posterior wall tracheal tears. They can be placed safely under conscious sedation at flexible bronchoscopy or under general anaesthetic at rigid bronchoscopy. Rigid bronchoscopy under general anaesthesia provided by a multidisciplinary team is safe with few contraindications. Complications of endobronchial stents include infection, granulation tissue formation and metallic stent fracture sometimes requiring removal, although serious life-threatening complications are very rare. Increasing numbers of patients are being referred to specialist centres for airway intervention. This article reviews the history of endobronchial stents, the different stents available, and the indications, outcomes and complications involved in deploying endobronchial stents.

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“…Central airway stenosis refers to the narrowing of the airway due to diseases causing airway lesions occurring in the trachea, the main bronchus, and the right medial segment, 1 and this includes both benign and malignant lesions. 2 , 3 The causes of malignant central airway stenosis are the metastasis of lung cancer, esophageal cancer, kidney cancer, etc. 4 Patients with central airway stenosis are often in critical condition, and if they do not receive timely treatment, this condition leads to death.…”

Section: Introductionmentioning

confidence: 99%

The clinical feasibility of flexible bronchoscopy interventional therapy in patients with central airway stenosis and respiratory failure caused by malignancy

Wang

Yang

Zha

et al. 2018

OTT

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ObjectiveThe aim of this study was to investigate the clinical effects and feasibility of using flexible bronchoscopy intervention in cases of malignancy that causes central airway stenosis and respiratory failure.MethodsThe clinical data of patients who were admitted to the Department of Respiratory Medicine at the First Affiliated Hospital of Nanjing Medical University and underwent treatment of a malignant tumor with central airway stenosis and respiratory failure by flexible bronchos-copy from February 2010 to May 2013 were analyzed using a retrospective method. The age, gender, location, extent of airway stenosis, interventional therapy, efficacy, and complications for 12 patients were collected and analyzed using the SPSS 13.0 software.ResultsAfter interventional therapy, the dyspnea index for all the patients improved signifi-cantly, and compared with before treatment, the difference was statistically significant (t=13.40, P<0.01). Eleven patients with respiratory failure were corrected, and only one patient was treated via tracheal intubation with mechanical ventilation. There were no severe complications, such as massive hemorrhaging or cardiac arrest in any case.ConclusionFlexible bronchoscopy interventional treatment for central airway stenosis and respiratory failure caused by malignant tumors is an effective and safe method. It should be applied in clinical work.

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Endoscopic Treatment of Central Airway Stenosis: Five Years' Experience

Cited by 20 publications

References 20 publications

Therapeutic bronchoscopic interventions for nonmalignant central airway obstruction provide rapid and sustained improvement in symptoms and functional status

Therapeutic bronchoscopic interventions for nonmalignant central airway obstruction provide rapid and sustained improvement in symptoms and functional status

Endobronchial stenting in the management of large airway pathology

The clinical feasibility of flexible bronchoscopy interventional therapy in patients with central airway stenosis and respiratory failure caused by malignancy

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