Endoscopic radiofrequency ablation for malignant biliary obstruction: a nationwide retrospective study of 84 consecutive applications

Dolak, Werner; Schreiber, F.; Schwaighofer, Hubert; Gschwantler, Michael; Plieschnegger, Wolfgang; Ziachehabi, A; Mayer, Andreas; Kramer, Ludwig; Kopecky, Andreas; Schrutka-Kölbl, C; Wolkersdörfer, Gernot W.; Madl, Christian; Berr, Frieder; Trauner, Michael; Püspök, Andreas

doi:10.1007/s00464-013-3232-9

Cited by 164 publications

(180 citation statements)

References 14 publications

Supporting

Mentioning

171

Contrasting

Unclassified

Order By: Relevance

“…Radiofrequency ablation seems to prolong survival in inoperable iCCA 256 . Intraductal radiofrequency ablation has been shown to be safe and feasible in the treatment of extrahepatic CCA 257 and seems to be a safe way of improving stent patency 258 . On the other hand, photodynamic therapy can improve survival in patients with unresectable CCA [259][260][261] .…”

Section: Locoregional Therapymentioning

confidence: 99%

Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)

Bañales

Cardinale

Carpino

et al. 2016

Nat Rev Gastroenterol Hepatol

Self Cite

997

1,058

View full text Add to dashboard Cite

Section: Locoregional Therapymentioning

confidence: 99%

Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)

Bañales

Cardinale

Carpino

et al. 2016

Nat Rev Gastroenterol Hepatol

Self Cite

997

1,058

View full text Add to dashboard Cite

“…Only three studies have reported a similar occurrence following intrabiliary RFA, including six cases of hemobilia and one case of hepatic artery pseudoaneurysm rupture (14,16,17). In the present case, endoscopy was performed to identify the bleeding site, but no injury or active bleeding was observed in the duodenum.…”

Section: A B C D F E Discussionmentioning

confidence: 58%

“…There have been reports of the use of intraductal RFA for the treatment of unresectable malignant biliary obstructions with percutaneous and endoscopic approaches, demonstrating its feasibility and safety; pain, cholangitis and asymptomatic biochemical pancreatitis have been reported as the only common complications (2,6,13), while hepatic coma, newly diagnosed left bundle branch block and partial liver infarction have been reported as uncommon complications (2,14,15). However, a few cases of hemobilia and mortality following intrabiliary RFA have also been reported (15).…”

Section: A B C D F E Discussionmentioning

confidence: 99%

Biliary tract perforation following percutaneous endobiliary radiofrequency ablation: A report of two cases

et al. 2016

View full text Add to dashboard Cite

Abstract. Endobiliary radiofrequency ablation (RFA) has recently been recognized as a beneficial treatment option for malignant biliary obstruction using percutaneous or endoscopic approaches. The feasibility and safety of this method has been demonstrated in clinical studies, with pain, cholangitis and asymptomatic biochemical pancreatitis reported as relatively common complications. By contrast, hepatic coma, newly diagnosed left bundle branch block and partial liver infarction have been reported as uncommon complications. Biliary tract perforation is a serious potential complication of percutaneous intraductal RFA, which may result in severe infection, peritonitis or even mortality, and which has not been previously reported in clinical research. The current study presents the first reports of biliary tract perforation in two patients with unresectable malignant biliary obstruction following percutaneous intraductal RFA. Although the patient in case 1 succumbed 12 days after RFA, the minor biliary tract perforation in case 2 was successfully treated by the deployment of a self-expanding metal stent. This study demonstrates that biliary tract perforation should be recognized as a serious potential complication of endobiliary RFA, and that metal stent deployment should be considered as a treatment option for minor biliary tract perforation.

show abstract

“…One case of partial liver infarction was reported in a patient with a Bismuth IV stage Klatskin tumor after RFA procedure. 51 No other serious complications have been reported so far. According to our knowledge, the endobiliary RFA technique has not been tested so far for clearance of occluded SEMS in malignant biliary obstruction.…”

Section: Biliary Tract Diseasesmentioning

confidence: 99%

Emerging indications of endoscopic radiofrequency ablation

et al. 2015

View full text Add to dashboard Cite

Introduction: Radiofrequency ablation (RFA) is a well-validated treatment of dysplastic Barrett's esophagus. Other indications of endoscopic RFA are under evaluation. Results: Four prospective studies (total 69 patients) have shown that RFA achieved complete remission of early esophageal squamous intra-epithelial neoplasia at a rate of 80%, but with a substantial risk of stricture. In the setting of gastric antral vascular ectasia, two prospective monocenter studies, and a retrospective multicenter study, (total 51 patients), suggest that RFA is efficacious in terms of reducing transfusion dependency. In the setting of chronic hemorrhagic radiation proctopathy, a prospective monocenter study and a retrospective multicenter study (total 56 patients) suggest that RFA is an efficient treatment. A retrospective comparative study (64 patients) suggests that RFA improves stents patency in malignant biliary strictures. Conclusions: Endoscopic RFA is an upcoming treatment modality in early esophageal squamous intra-epithelial neoplasia, as well as in gastric, rectal, and biliary diseases.

show abstract

Endoscopic radiofrequency ablation for malignant biliary obstruction: a nationwide retrospective study of 84 consecutive applications

Cited by 164 publications

References 14 publications

Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)

Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)

Biliary tract perforation following percutaneous endobiliary radiofrequency ablation: A report of two cases

Emerging indications of endoscopic radiofrequency ablation

Contact Info

Product

Resources

About