Endoscopic findings and lesion distribution in amebic colitis

Horiki, Noriyuki; Furukawa, Keiichi; Kitade, Takashi; Sakuno, Takashi; Katsurahara, Masaki; Harada, Togoro; Tano, Shunsuke; Yamada, Reiko; Hamada, Yasuhiko; Inoue, H.; Tanaka, Kyosuke; Gabazza, Esteban C.; Ishii, Naoki; Fukuda, Katsuyuki; Fujita, Yoshiyuki; Tachibana, Hiroshi; Takei, Yoshiyuki

doi:10.1016/j.jiac.2015.02.004

Cited by 18 publications

(15 citation statements)

References 19 publications

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“…18,30 Recently, the endoscopic procedure has been cited as a potential tool for early diagnosis of amebiasis and for prevention of serious complications. 17 This study, based on nationally reported surveillance data, has several limitations. First, information regarding route of infection were self-reported surveillance data, and self-reported sexual activity information may be inaccurate.…”

Section: Discussionmentioning

confidence: 96%

“…For the suspected route of infection, physicians could choose from the following five routes: 1) homosexual (sexual contact with someone of the same gender), 2) heterosexual (sexual contact with someone of the opposite gender), 3) sexual unspecified (indicated as sexual infection but not specified as homosexual or heterosexual), 4) nonsexual (infection attributed to contaminated food or water), and 5) unknown (none of (1) through (4) apply). In this study, cases with specific colonic mucosa lesions, such as erythema, edematous mucosa, erosion, white exudates, and ulcers, 15,17 but otherwise asymptomatic and reported through NESID, were classified as asymptomatic cases.…”

Section: Methodsmentioning

confidence: 99%

“…12,13 And, for domestically acquired infections, while MSM have been known to be a high risk group, [14][15][16] recently, there have been clinical reports of non-MSM, particularly mild cases, diagnosed by colonoscopy in Japan. [17][18][19] Therefore, to assess the possible reasons for the recent increase in domestically acquired infections, our objective in this study was to describe the recent epidemiology of domestic amebiasis in Japan, with a particular focus on potential risk groups.…”

Section: Introductionmentioning

confidence: 99%

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Epidemiology of Domestically Acquired Amebiasis in Japan, 2000–2013

Ishikane¹,

Arima²,

Kanayama³

et al. 2016

The American Society of Tropical Medicine and Hygiene

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Abstract. Notifications of amebiasis have been increasing in Japan. Using national surveillance data during 2000-2013, reported cases of amebiasis were analyzed. A case of amebiasis was defined as laboratory-confirmed Entamoeba histolytica infection, regardless of presence of symptoms. We described temporal trends and analyzed correlates of asymptomatic versus symptomatic cases based on odds ratios (ORs) and 95% confidence intervals (CIs) using logistic regression. Of 9,946 cases reported during 2000-2013, 7,403 were domestic cases. During this period, the proportion of domestic cases increased from 63% to 85%. Among male cases, majority were middle aged, and from 2008, the number of cases attributed to heterosexual contact surpassed that of homosexual contact. During 2010-2013, increase in notifications was associated with asymptomatic cases, colonoscopy diagnosis, and males with unknown or heterosexual route of infection. Among males, colonoscopy (OR = 31.5; 95% CI = 14.0-71.0) and cases with unknown route of infection, relative to homosexual contact (OR = 2.2; 95% CI = 1.3-3.9), were associated with asymptomatic infections in multivariate analysis. Although the recent rise may have been due to enhanced detection by colonoscopy or reporting, the large number of asymptomatic cases, with reportedly unknown or heterosexual route of infection, has led to a better understanding of amebiasis in Japan and highlights the potential public health concern.

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Section: Discussionmentioning

confidence: 96%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Epidemiology of Domestically Acquired Amebiasis in Japan, 2000–2013

Ishikane¹,

Arima²,

Kanayama³

et al. 2016

The American Society of Tropical Medicine and Hygiene

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“…This lectin also plays a role in immunity following colonization. One study from Bangladesh showed that children with a mucosal IgA response against the lec- Cecum and colon are the most common sites of involvement [27]. The characteristic endoscopic findings of amebic colitis have been reported in the cecum, rectum, ascending colon, transverse colon, sigmoid colon, and descending colon as 93, 45, 28, 25, 20, and 15 percent, respectively [27].…”

Section: Antigen Testingmentioning

confidence: 99%

An Unusual Case of Entamoeba Histolytica Infection in Miami Fl: Case Report and Review of the Literature

Tahir¹,

Shane²,

Amar³

et al. 2020

Res Rev Infect Dis

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We report a case of E. histolytica, which is a rare parasitic infection in North America. A 66-year-old Ecuadorian female had an intermittent six-month history of bloating, explosive diarrhea and significant abdominal distension. Histopathological specimen obtained via colonoscopy revealed colitis due to E. histolytica. Diagnosis is best accomplished by the combination of serology or antigen testing together with identification of the parasite in the stool or extra-intestinal sites or histologic examination when necessary. With medical tourism and an increase of immigrants from South and Central America, disease endemic to those areas should always be considered.

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“…Early and accurate diagnosis is extremely important. Some endoscopic and histologic features could be useful for differential diagnosis [9][10][11] . But in non-endemic countries and area, the amebic colitis is still often misdiagnosed.…”

Section: Introductionmentioning

confidence: 99%

Characteristics of Endoscopic and Pathological Findings of Amebic Colitis

Yue

meng

Zhou

et al. 2020

Preprint

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Backgroud The clinical features of amoebic colitis resemble those of inflammatory bowel Disease(IBD), and therefore the risk of misdiagnosis is very high.Objective The aim of this study was to analyse the characteristics of the endoscopic and pathological findings of amebic colitis and the lessons from our patients, which were useful for diagnosing the amebic colitis timely and avoiding the serious complications.Methods We retrospectively reviewed data of all amebic colitis admitted to Beijing Friendship Hospital from January 2015 to January 2020. Cases were diagnosed by clinical presentation, laboratory examinations, and colonoscopy with biopsy and histological examination. Results 16 patients were diagnosed with amebic colitis by the colonscopy accompanied by biopsy and microscopic examination. At first time, 12 (75%) patients were misdiagnosed as IBD. Cecum was the most common site of amebic colitis(100%), and the caecum and rectum were also involved in many lesions(68.75%). Multiple lesions of erosion and/or ulcer were recognized in all patients(100%).The features of endoscopic findings included multiple irregular shaped ulcers and erosions with surrouding erythema, and the ulcers and erosions were covered by the white or yellow exudates. The intervening mucosae between the ulcers or erosions were normal. The features of rectums can be divided to 2 types: in 6 patients(54.5%), the irregular ulcer or erosions covered with white or yellow exudates were observed in rectum and cecum, and the bloody exudates in rectum were more severe than those in cecum; in other 5 patients(45.5%), rectal lesions were much less severe than those in cecum, the small superficial erosion or reddened mucosa were observed in the rectal ampulla. All patients were diagnosed as detection of amebic trophozoites from HE-stained biopsy specimens. The number of trophozoites ranged from 1 /HPF to ＞50/HPF. Among 16 cases, mild architectural alteration of colon crypt were observed in 10 cases(62.5%), and serious architectural alteration of colon crypt was found which had crypt branch in 1 case(16.7%). Cryptitis was observed in 12 cases(75%) and its severity was mild or moderate. No crypts abscess was observed in all cases. Conclusions The colonoscopy with histological examination are very important to diagnose the amebic colitis. Detect the amoebic trophozoites in the esudates by histological examination is the vital. Sometimes a negative biopsy does not rule out amebiasis, repeated biopsies may be needed to make the diagnosis.

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Endoscopic findings and lesion distribution in amebic colitis

Cited by 18 publications

References 19 publications

Epidemiology of Domestically Acquired Amebiasis in Japan, 2000–2013

Epidemiology of Domestically Acquired Amebiasis in Japan, 2000–2013

An Unusual Case of Entamoeba Histolytica Infection in Miami Fl: Case Report and Review of the Literature

Characteristics of Endoscopic and Pathological Findings of Amebic Colitis

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