Endoscopic Ethmoidectomy and Maxillary Antrostomy in Immunodeficient Patients

Lusk, Rodney P.; Polmar, Stephen H.; Muntz, Harlan R.

doi:10.1001/archotol.1991.01870130066018

Cited by 34 publications

(14 citation statements)

References 11 publications

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“…In general, broad-spectrum antibiotics, saline nasal washes, anti-inflammatory agents, and immunoglobulin replacement therapy could reduce the frequency and severity of sinusitis in PID patients [18,25]. While the role of sinus surgery has not been well defined, it seems that PID patients experience similar benefits to immunocompetent populations in terms of symptoms and quality of life [26][27][28][29]. If the response to surgery of patients with PID is similar to that of the general population with chronic sinusitis, earlier surgery has been shown to decrease the harmful effects of chronic sinusitis [30].…”

Section: Sinusitismentioning

confidence: 99%

Infectious and Noninfectious Pulmonary Complications in Patients With Primary Immunodeficiency Disorders

Yazdani

Abolhassani

et al. 2017

J Investig Allergol Clin Immunol

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Primary immunodeficiency disorders (PIDs) are caused by 1 or more defects of the immune system. Patients are more likely to experience recurrent and/or severe infections and tend to develop a wide range of complications. Respiratory diseases are the main and initial manifestation in most cases and the most common complication. Pulmonary complications cause significant morbidity and mortality in patients with PIDs. Early diagnosis and appropriate treatment can prevent or at least slow the development of respiratory complications. Since the spectrum of pulmonary complications in PIDs is broad, we divided pulmonary complications into upper respiratory complications (eg, sinusitis, otitis media, and laryngeal angioedema) and lower respiratory complications (eg, pneumonia, bronchitis, bronchiectasis, interstitial lung diseases, organizing pneumonia, pulmonary adenopathies and malignancies, hyperreactive airway diseases, pulmonary dysgenesis, and adverse reactions to treatment). This review covers the main respiratory manifestations in patients with PIDs. Key words: Primary immunodeficiency disorders. Pulmonary complications. Upper respiratory tract. Lower respiratory tract. ResumenLas inmunodeficiencias primarias (PIDs) son enfermedades causadas por uno o más defectos del sistema inmunológico. Estos pacientes presentan con frecuencia infecciones recidivantes y/o severas así como otro tipo de complicaciones. Las patologías respiratorias son la principal y más frecuente manifestación y complicación de las PIDs. Las complicaciones de estas patologías pulmonares constituyen una de las principales causas de morbimortalidad entre los pacientes que sufren PIDs. El diagnóstico temprano y el tratamiento adecuado pueden prevenir, o al menos retrasar, la aparición de las complicaciones respiratorias en estos pacientes. Dado que el espectro de las enfermedades pulmonares es muy amplio, hemos dividido estas complicaciones entre aquellas que afectan a las vías aéreas superiores (sinusitis, otitis media y angioedema laríngeo, etc.) y las que afectan a las vías aéreas bajas (neumonía, bronquitis, bronquiectasias, enfermedades pulmonares intersticiales, neumonía organizada, adenopatías pulmonares y neoplasias, hiperreactividad bronquial, disgenesia pulmonar y las debidas a los efectos secundarios del tratamiento instaurado). Este artículo revisa las manifestaciones respiratorias que se observan más frecuentemente en los pacientes con PIDs. Palabras clave: Inmunodeficiencias primarias. Complicaciones pulmonares. Vías respiratorias altas. Vías respiratorias bajas.

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Section: Sinusitismentioning

confidence: 99%

Infectious and Noninfectious Pulmonary Complications in Patients With Primary Immunodeficiency Disorders

Yazdani

Abolhassani

et al. 2017

J Investig Allergol Clin Immunol

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“…27,28 Surgery is typically limited to maxillary antrostomy and anterior ethmoidectomy, only including posterior ethmoidectomy if significant disease persists after medical therapy has failed. In relatively short follow-up periods, Lusk et al 32 found that most patients improved after surgery in terms of symptoms and none worsened, although most required continued medical therapy, usually gamma globulin.…”

Section: Resultsmentioning

confidence: 99%

“…35,41 When treating the pediatric population, most authors support thorough medical management prior to invasive procedures. 12,27,32 IVIG has been shown to be effective in this population, again mainly for pulmonary complications in children with more severe forms of immunodeficiency.…”

Section: Discussionmentioning

confidence: 99%

“…13,27,28,32 If these patients have a similar response to surgery as the general population with CRS, recent papers in rhinology literature suggest that earlier surgical intervention minimizes deleterious effects of chronic inflammatory sinusitis. 42,43 Intervening early may improve symptom scores and reduce the number of oral medications (antibiotics and steroids) prescribed.…”

Section: Discussionmentioning

confidence: 99%

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Primary immunodeficiency and recalcitrant chronic sinusitis: a systematic review

Mazza

Lin

2016

Int Forum Allergy Rhinol.

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Patients with recalcitrant CRS should be evaluated for primary immunodeficiency. This should include as assessment of quantitative serum immunoglobulin levels as well as functional antibody responses. Medical therapy, particularly immunoglobulin replacement therapy, appears to be most effective when administered at high doses early in the disease course. The addition of surgery is less clearly supported, but may also provide benefit if performed early.

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“…It has revolutionized sinus surgery and has been reported to improve clinical outcome for patients with chronic and recurrent sinusitis. [15][16][17][18][19][20][21] Endoscopic sinus surgery is generally indicated when maximal medical treatment fails to resolve the patient's symptoms. However, maximal medical treatment is not clearly defined, and the basis for selection of medical vs surgical treatment in patients with chronic sinusitis is not universally accepted.…”

mentioning

confidence: 99%

The Impact of Sinus Computed Tomography on Treatment Decisions for Chronic Sinusitis

Anzai

Weymuller

Yueh

et al. 2004

Arch Otolaryngol Head Neck Surg

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Endoscopic Ethmoidectomy and Maxillary Antrostomy in Immunodeficient Patients

Cited by 34 publications

References 11 publications

Infectious and Noninfectious Pulmonary Complications in Patients With Primary Immunodeficiency Disorders

Infectious and Noninfectious Pulmonary Complications in Patients With Primary Immunodeficiency Disorders

Primary immunodeficiency and recalcitrant chronic sinusitis: a systematic review

The Impact of Sinus Computed Tomography on Treatment Decisions for Chronic Sinusitis

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