Endoscopic diagnosis and management of pleural effusion in malignant pleural mesothelioma

Ceruti, Paolo; Lonni, Sara; Baglivo, Francesca; Marchetti, Giampietro

doi:10.21037/jtd.2017.09.142

Cited by 8 publications

(5 citation statements)

References 32 publications

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“…Because little is known about the natural course of SELs, the appropriate strategy ournal J Pharmaceutical and Medical for management remains controversial. Although it was not part of the objectives, it was found that endoscopic follow-up of the lesions was carried out in 5 cases, 3 were (at 10 mm and none of the latter changed their size or characteristics in 12 months These findings, although descriptive, are consistent with previous studies that have suggested, given that the majority of small SELs ((10 mm) do not present changes that increase the suspicion of malignant potential in the medium term, a conservative policy with endoscopic surveillance it is a safe strategy [24,26].…”

Section: Resultssupporting

confidence: 90%

“…The technique of "biopsies on biopsies" has been initially described for acquiring tissue from hypoechoic lesions of the fourth layer. However, some studies showed a low diagnostic yield of around 17% (22,24). In the study under discussion, this technique was performed in 11% of SELs, not achieving a histological diagnosis, which is consistent with the above.…”

Section: Resultssupporting

confidence: 80%

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Leptin Hormone: In Brief

Al-Hussaniy

Altalebi

Tylor³

et al. 2022

Med Pharm J.

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There is a lot of research and information on drugs and treatments, but a questionnaire was conducted to find out the degree of knowledge of doctors and medical personnel in general about the hormone leptin. It was found that many people do not know what leptin is and what it's a role in the body Leptin is a hormone that plays a key role in energy consumption and regulation of energy consumption. Leptin hormone is one of the hormones that have a basic role in many vital functions of the body, and this hormone has been called many names, based on its work in the body, and the most prominent of these names are; The obesity hormone, the hunger hormone, and the fat hormone as well (1), Leptin hormone is known as a peptide hormone that is produced and secreted by fat cells responsible for regulating body weight, acting on the hypothalamus in order to reduce appetite, in addition to working to burn fat stored in adipose tissue. The hormone leptin has also been known as the hunger hormone or the satiety hormone; Because it is the hormone responsible for sending some

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Section: Resultssupporting

confidence: 90%

Section: Resultssupporting

confidence: 80%

Leptin Hormone: In Brief

Al-Hussaniy

Altalebi

Tylor³

et al. 2022

Med Pharm J.

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“…In contrast to discrete distribution pattern of a benign disease, malignant pleural lesions were likely to appear as fused and bulging nodules of various sizes on pleuroscopic examination [20]. The rapid growth of cancer cells and central necrosis pattern may result in the appearance of these lesions.…”

Section: Discussionmentioning

confidence: 92%

Diagnosis of Tuberculosis Pleurisy with Three Endoscopic Features via Pleuroscopy

Lee

Chang

et al. 2020

Preprint

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Background: Tuberculosis (TB) is a constant threat even with worldwide active public health campaign. Diagnosis of TB pleurisy is challenging in case of pleural effusion of unknown origin after aspiration analysis. The study was designated to demonstrate a simple image interpretation technique to differentiate TB pleurisy from non-TB pleurisy using semi-rigid pleuroscopy. Methods: The study retrospectively enrolled 117 patients who underwent semi-rigid pleuroscopy from April 2016 to August 2018 in a tertiary hospital. We analyzed the possibility of TB pleurisy using three simple pleuroscopic images via semi-rigid pleuroscopy. Results: Among 117 patients, 28 patients (23.9%) were diagnosed with TB pleurisy. Sago-like nodules/micronodules, adhesion, and discrete distribution were noted in 20 (71.4%), 20 (71.4%), and 19 (67.9%) patients with TB pleurisy, respectively. Sago-like nodules/micronodules, adhesion, and discrete distribution were noted in 6 (6.7%), 37 (41.6%), and 0 (0.0%) patients with non-TB pleurisy, respectively. The positive and the negative predictive values of any two out of three pleuroscopic patterns for TB pleurisy were 100.0% and 93.7%, respectively. Conclusions: A high positive predictive value for TB pleurisy was demonstrated by the presence of any two out of the three characteristic features. Absence of all three features had an excellent negative predictive value for TB pleurisy. Our diagnostic criteria reconfirm that pleuroscopic images can be used as predictors for TB pleurisy.

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“…In contrast to the discrete distribution pattern of a benign disease, malignant pleural lesions were likely to appear as fused and bulging nodules of various sizes on pleuroscopic examination. 23 The rapid growth of cancer cells and central necrosis pattern may result in the appearance of these lesions. Considering the pathophysiology of TB pleurisy with rupture of antigens into the pleural cavity causing diffuse hypersensitivity reaction, discrete distribution of lesions is a reasonable presentation for TB pleurisy.…”

Section: Discussionmentioning

confidence: 99%

Diagnosis of tuberculosis pleurisy with three endoscopic featuresviapleuroscopy

Lee

Chang

et al. 2021

Ther Adv Respir Dis

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Background: Tuberculosis (TB) is a constant threat even with a worldwide active public health campaign. Diagnosis of TB pleurisy is challenging in the case of pleural effusion of unknown origin after aspiration analysis. The study was designed to demonstrate a simple image interpretation technique to differentiate TB pleurisy from non-TB pleurisy using semi-rigid pleuroscopy. Methods: The study retrospectively enrolled 117 patients who underwent semi-rigid pleuroscopy from April 2016 to August 2018 in a tertiary hospital. We analyzed the possibility of TB pleurisy using three simple pleuroscopic images via semi-rigid pleuroscopy. Results: Among 117 patients, 28 patients (23.9%) were diagnosed with TB pleurisy. Sago-like nodules/micronodules, adhesion, and discrete distribution were noted in 20 (71.4%), 20 (71.4%), and 19 (67.9%) patients with TB pleurisy, respectively. Sago-like nodules/micronodules, adhesion, and discrete distribution were noted in six (6.7%), 37 (41.6%), and no (0.0%) patients with non-TB pleurisy, respectively. The positive and negative predictive values of any two out of three pleuroscopic patterns for TB pleurisy were 100.0% and 93.7%, respectively. Conclusions: A high positive predictive value for TB pleurisy was demonstrated by the presence of any two out of the three characteristic features. Absence of all three features had an excellent negative predictive value for TB pleurisy. Our diagnostic criteria reconfirm that pleuroscopic images can be used as predictors for TB pleurisy in patients with undiagnosed pleural effusion. The reviews of this paper are available via the supplementary material section.

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Endoscopic diagnosis and management of pleural effusion in malignant pleural mesothelioma

Cited by 8 publications

References 32 publications

Leptin Hormone: In Brief

Leptin Hormone: In Brief

Diagnosis of Tuberculosis Pleurisy with Three Endoscopic Features via Pleuroscopy

Diagnosis of tuberculosis pleurisy with three endoscopic featuresviapleuroscopy

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