Endorectal magnetic resonance imaging of prostatic cancer: comparison between fat-suppressed T2-weighted fast spin echo and three-dimensional dual-echo, steady-state sequences

Ikonen, S.; Kärkkäinen, Päivi; Kivisaari, Leena; Salo, J.; Taari, Kimmo; Vehmas, Tapio; Tervahartiala, Pekka; Rannikko, S.

doi:10.1007/s003300000598

Cited by 68 publications

(33 citation statements)

References 15 publications

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“…Ikonen et al 8 showed that 77% of the patients had visible hemorrhage on endorectal magnetic resonance imaging after a single biopsy, and found that it took 28 days for a radiologically obvious decrease in the amount of blood. This postbiopsy hemorrhage can lead to periprostatic inflammation and fibrosis, obliterating surgical planes of dissection, and making a future operation more technically challenging.…”

Section: Discussionmentioning

confidence: 99%

The impact of multiple biopsies on outcomes of nerve-sparing robotic-assisted radical prostatectomy

et al. 2012

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Active surveillance of prostate cancer patients involves subjecting them to multiple prostate biopsies, and we sought to investigate the effects of this on functional outcomes after robotic-assisted radical prostatectomy (RARP). Between May 2009 and December 2009, 367 patients who consecutively underwent RARP by a single surgeon were divided into two groups, one that had single prostate biopsy and another multiple biopsies before RARP. The groups were matched for significant clinicopathologic preoperative variables, and only premorbidly potent low-risk cases that underwent nerve sparing were included. This left 50 and 23 patients for analysis in the single and multiple biopsy groups, respectively. The primary endpoint was potency and continence at 3 and 6 months after surgery. We found continence rates of 84% (83%) and 94% (96%) for single (multiple) biopsy groups at 3 and 6 months, respectively (P ¼ 0.88, P ¼ 0.77). Multiple biopsy patients had worse postoperative erectile function at 6 months (57% versus 80%, P ¼ 0.03). Men subject to multiple preoperative biopsies are more likely to become impotent postoperatively than those who undergo surgery after a single biopsy. This should be borne in mind when counseling men regarding repeat biopsy as part of an active surveillance strategy.

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Section: Discussionmentioning

confidence: 99%

The impact of multiple biopsies on outcomes of nerve-sparing robotic-assisted radical prostatectomy

et al. 2012

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“…Magnetic resonance imaging (MRI) has gained clinical acceptance in the preoperative evaluation of prostatic carcinoma patients in terms of extracapsular spread, seminal vesicle-neurovascular bundle invasion, lymph node metastases in patients with biopsy proven prostatic carcinoma [1]. On the other hand, the accuracy of T2-weighted sequences in the diagnosis of prostate cancer is limited, due to lack of sensitivity and specificity [2,3]. Both prostatitis and tumoral infiltration have overlapping features and are seen as decreased signal intensity foci on conventional T2-weighted images [1,4].…”

Section: Introductionmentioning

confidence: 99%

Diffusion tensor imaging of the normal prostate at 3 Tesla

et al. 2007

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The aim of this study was to assess the feasibility of diffusion tensor imaging (DTI) of the prostate and to determine normative fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values of healthy prostate with a 3-Tesla magnetic resonance imaging (MRI) system. Thirty volunteers with a mean age of 28 (25-35) years were scanned with a 3-Tesla MRI (Intera Achieva; Philips, The Netherlands) system using a six-channel phased array coil. Initially, T2-weighted turbo spin-echo (TSE) axial images of the prostate were obtained. In two subjects, a millimetric hypointense signal change was detected in the peripheral zones on T2-weighted TSE images. These two subjects were excluded from the study. DTI with single-shot echo-planar imaging (ssEPI) was performed in the remaining 28 subjects. ADC and FA values were measured using the manufacturer supplied software by positioning 9-pixel ROIs on each zone. Differences between parameters of the central and peripheral zones were assessed. Mean ADC value of the central (1.220 +/- 0.271 x 10(-3) mm(2)/s) was found to be significantly lower when compared with the peripheral gland (1.610 +/- 0.347 x 10(-3) mm(2)/s) (P < 0.01). Mean FA of the central gland was significantly higher (0.26), compared with the peripheral gland (0.16) (P < 0.01). This study shows the feasibility of prostate DTI with a 3-Tesla MR system and the normative FA and ADC values of peripheral and central zones of the normal prostate. The results are compatible with the microstructural organization of the gland.

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“…Furthermore, these results are valid only for examinations performed with a phased-array coil and that they cannot be extrapolated to examinations performed with an endorectal coil. Approximately 70% of cases in prostate cancer arise in the peripheral zone [24], and the accuracy of tumor detection for cancers originating in the peripheral zone using MR imaging is reported to be approximately 50-70% [7,8,9,10]. The remaining prostate cancer cannot be detected because the lesions were essentially isointense to the peripheral zone [25].…”

Section: Discussionmentioning

confidence: 99%

“…The most cancer nodules arise in the peripheral zone and are of low signal intensity compared with an inherently high signal intensity of the peripheral zone by this method. Since 512 matrix can be used in T2-weighted FSE imaging either with body coil or endorectal surface coil, high spatial resolution is obtained with a short acquisition time; however, the limitation of conventional or FSE imaging also exists and 30-40% of prostate cancer in the peripheral zone are undetectable because the lesions are isointense to the peripheral zone [7,8,9,10].…”

Section: Introductionmentioning

confidence: 99%

T2-weighted MR imaging of prostate cancer: multishot echo-planar imaging vs fast spin-echo imaging

et al. 2004

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The aim of the present study was to assess the performance of pre-biopsy T2-weighted MR imaging using multishot echo-planar imaging (EPI) sequence for visualization of prostate cancer and to compare image quality with that of fast spin-echo (FSE) sequence. Thirty-nine patients with suspected prostate cancer and one healthy male volunteer were examined on a 1.5-T MR scanner equipped with a pelvic phased-array coil. Axial MR images were obtained using multishot EPI sequence with a multishot number of 16 and FSE sequence without fat suppression. Paired EPI and FSE images were independently evaluated by three radiologists. Furthermore, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were compared between EPI and FSE images of 12 pathologically proven lesions of prostate cancer. Delineation of the periprostatic venous plexus, prostate zonal anatomy, and seminal vesicle on EPI was graded to be superior/inferior to FSE in 15.8/0, 14.6/0, and 21.5/4.3% of cases, respectively. On the other hand, delineation of the neurovascular bundle was superior/inferior to FSE in 2.6/13.2% of cases. The SNR and CNR of prostate cancer on EPI were significantly higher than those on FSE (7.99 +/- 2.51 vs 3.36 +/- 0.58, p<0.0001, and 5.51 +/- 2.02 vs 2.21 +/- 0.79, p<0.0001, respectively). In conclusion, multishot EPI has higher quality of contrast resolution for imaging of prostate cancer compared with FSE and would have the potential usefulness in the detection of prostate cancer, although these results obtained with a phased-array coil cannot be extrapolated to examinations performed with an endorectal coil.

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Endorectal magnetic resonance imaging of prostatic cancer: comparison between fat-suppressed T2-weighted fast spin echo and three-dimensional dual-echo, steady-state sequences

Cited by 68 publications

References 15 publications

The impact of multiple biopsies on outcomes of nerve-sparing robotic-assisted radical prostatectomy

The impact of multiple biopsies on outcomes of nerve-sparing robotic-assisted radical prostatectomy

Diffusion tensor imaging of the normal prostate at 3 Tesla

T2-weighted MR imaging of prostate cancer: multishot echo-planar imaging vs fast spin-echo imaging

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