Diffusion tensor imaging of the normal prostate at 3 Tesla

Gürses, Bengı; Kabakci, Neslihan; Kovanlıkaya, Arzu; Fırat, Zeynep; Bayram, Ali; Uluğ, Aziz M.; Kovanlıkaya, İlhami

doi:10.1007/s00330-007-0795-7

Cited by 55 publications

(41 citation statements)

References 21 publications

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“…Table 1 gives the ADC values reported by various researchers. The potential of DWI and T2-weighted imaging in prostate cancer detection has been reported at 3T [42][43][44][45]. At 3T, a considerable overlap of ADC values was observed in proven cases of cancer and the normal PZ in patients [42].…”

Section: Diffusion-weighted Imagingmentioning

confidence: 96%

“…The role of in vivo MRS, MRSI, and DWI in prostate cancer is clear from the materials presented in this review as well from the literature data [17][18][19][20][21][22][23][24][25][34][35][36][37][38][39][40][41][42][43][44][45][46]. The malignant transformation of cells and progress is associated both with metabolic and tissue architectural changes.…”

Section: Combined Use Of Mrsi and Dwimentioning

confidence: 99%

“…With the use of endorectal MRI, the potential of diagnosis and preoperative staging has increased. Studies have been reported on the use of endorectal MRI [17][18][19][20][21][22][23][24][25][26][27][28][29][30][31], MRS and MRSI [17][18][19][20][21][22][23][24][25]29,31,32], diffusionweighted imaging (DWI) [33][34][35][36][37][38][39][40][41][42][43][44][45][46], and dynamic contrastenhanced MR imaging (DCE-MRI) [54][55][56][57][58][59][60][61][62]…”

Section: Introductionmentioning

confidence: 99%

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Role of magnetic resonance methods in the evaluation of prostate cancer: an Indian perspective

Jagannathan

Kumar

et al. 2008

Magn Reson Mater Phy

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The challenges in detection, localization, and staging of prostate cancer have prompted the investigation of the role of various magnetic resonance (MR) methodologies in a large cohort of men prior to biopsy. The identification of suspicious areas of malignancy was carried out using magnetic resonance imaging (MRI), magnetic resonance spectroscopic imaging (MRSI) and diffusion-weighted imaging (DWI). Our data shows that apparent diffusion coefficient (ADC) may be a reliable marker to differentiate normal, benign, and malignant prostate tissues similar to the metabolite ratio. Also, the combined use of MRSI and DWI improves the diagnosis of prostate cancer. In this review, we present our experience on the use of MRI, MRSI and DWI methods in the assessment of prostate cancer in Indian men. Further, analysis of the comparison of the ADC and the metabolite ratio values reported in the literature across various patient populations are presented.

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Section: Diffusion-weighted Imagingmentioning

confidence: 96%

Section: Combined Use Of Mrsi and Dwimentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Role of magnetic resonance methods in the evaluation of prostate cancer: an Indian perspective

Jagannathan

Kumar

et al. 2008

Magn Reson Mater Phy

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“…This anisotropic behaviour "can be detected by observing differences in diffusivity by using diffusion gradients in at least six directions". Diffusion tensor imaging has been used predominantly for brain imaging [37,38] with limited data for body imaging of liver [39,40] , kidneys [41][42][43] , breast [44] and prostate [45] .…”

Section: Dw Imaging In Biological Tissuementioning

confidence: 99%

Diffusion-weighted magnetic resonance imaging in cancer: Reported apparent diffusion coefficients,in-vitroandin-vivoreproducibility

Jafar

Parsaï

Miquel

2016

WJR

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There is considerable disparity in the published apparent diffusion coefficient (ADC) values across different anatomies. Institutions are increasingly assessing repeatability and reproducibility of the derived ADC to determine its variation, which could potentially be used as an indicator in determining tumour aggressiveness or assessing tumour response. In this manuscript, a review of selected articles published to date in healthy extracranial body diffusion-weighted magnetic resonance imaging is presented, detailing reported ADC values and discussing their variation across different studies. In total 115 studies were selected including 28 for liver parenchyma, 15 for kidney (renal parenchyma), 14 for spleen, 13 for pancreatic body, 6 for gallbladder, 13 for prostate, 13 for uterus (endometrium, myometrium, cervix) In addition, six phantom studies and thirteen in vivo studies were summarized to compare repeatability and reproducibility of the measured ADC. All selected phantom studies demonstrated lower intra-scanner and inter-scanner variation compared to in vivo studies. Based on the findings of this manuscript, it is recommended that protocols need to be optimised for the body part studied and that system-induced variability must be established using a standardized phantom in any clinical study. Reproducibility of the measured ADC must also be assessed in a volunteer population, as variations are far more significant in vivo compared with phantom studies. Core tip: Diffusion-weighted magnetic resonance imaging was highlighted as a potential cancer imaging biomarker by a team of experts in a report published in 2009. We review the variability of published diffusion values in the major extra-cranial organs and focus on the validation literature, both in vivo and in vitro . A total of 115 studies were selected including for liver parenchyma, kidney, pancreatic body, spleen, gallbladder, prostate, uterus (endometrium, myometrium, cervix) and breast. We also look in detail at the published repeatability and reproducibility studies, both in vivo and in phantoms. A series of recommendations based on our findings are given at the end of this review.Jafar MM, Parsai A, Miquel ME. Diffusion-weighted magnetic resonance imaging in cancer: Reported apparent diffusion coefficients, in vitro and in vivo reproducibility.

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“…FA is obtained by using at least six tensor applications, which provides directional data about diffusion anisotropy [14]. …”

Section: Introductionmentioning

confidence: 99%

Relationship between the Phase Value of ESWAN and Fractional Anisotropy of Diffusion Tensor Imaging in Patients with Cerebral Microbleeds: Preliminary Results

Guo

Geng²,

Zhu

et al. 2013

Eur Neurol

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Aims: The purpose of the present study was to measure phase values (PVs) and fractional anisotropy (FA) of cerebral microbleeds (CMBs) using phase and FA map, and to investigate the potential relationship between PVs and FAs in CMBs in vivo. Methods: We retrospectively analyzed 30 patients with CMBs using enhanced T2*-weighted angiography and diffusion tensor imaging. The PVs and FAs of CMBs were measured and documented, and the mean FAs were compared between CMBs and the corresponding normal brain tissue. The mean PVs were correlated with FAs in CMBs in seven different brain regions. Results: A total of 106 CMBs were defined, and the mean FA of the CMBs in white matter, EC/IC/CR, thalamus, and cerebellum were significantly lower than that of normal brain tissue in the control group (p < 0.05). Positive correlations were observed between the PV and FA of CMBs in white matter, external capsule, internal capsule and corona radiata (r = 0.70, 0.38). Conclusion: Enhanced T2*-weighted angiography and diffusion tensor imaging sequence may be useful neuroimaging sequences that could reflect the severity of damage of white matter by measuring the FA of CMBs and provide useful reference data for the quantitative assessment of CMBs.

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Diffusion tensor imaging of the normal prostate at 3 Tesla

Cited by 55 publications

References 21 publications

Role of magnetic resonance methods in the evaluation of prostate cancer: an Indian perspective

Role of magnetic resonance methods in the evaluation of prostate cancer: an Indian perspective

Diffusion-weighted magnetic resonance imaging in cancer: Reported apparent diffusion coefficients,in-vitroandin-vivoreproducibility

Relationship between the Phase Value of ESWAN and Fractional Anisotropy of Diffusion Tensor Imaging in Patients with Cerebral Microbleeds: Preliminary Results

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