Endophytic Fungi: Recent Advances in Identification and Explorations

Kumar, Vinay; Soni, Ravindra; Jain, Lata; Dash, Bisnu Prasad; Goel, Reeta

doi:10.1007/978-3-030-03589-1_13

Cited by 24 publications

(10 citation statements)

References 102 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, the antimicrobial, herbicidal and algicidal agents from chlorinated metabolites cryptosporiopsin (+) and mycorrhizin A (-) from endophytic Pezicula strains have been documented [ 57 ]. Similarly, the antifungal activity of chlorinated benzophenone derivatives such as Pestalachlorides A with the chemical formula (C 21 H 21 C l2 NO 5 ) and Pestalachlorides B with the chemical formula (C 20 H 18 C l2 O 5 ) extracted from the plant endophytic fungus Pestalotiopsis adusta against fungal plant pathogens Verticillium albo-atrum , Gibberella zeae , and Fusarium culmorum have been documented [ 58 ].…”

Section: Pharmacological Effects Of Bioactive Compounds Of Fungal mentioning

confidence: 99%

Pharmacological Potential of Fungal Endophytes Associated with Medicinal Plants: A Review

Adeleke

Babalola

2021

JoF

View full text Add to dashboard Cite

Endophytic microbes are microorganisms that colonize the intracellular spaces within the plant tissues without exerting any adverse or pathological effects. Currently, the world population is facing devastating chronic diseases that affect humans. The resistance of pathogens to commercial antibiotics is increasing, thus limiting the therapeutic potential and effectiveness of antibiotics. Consequently, the need to search for novel, affordable and nontoxic natural bioactive compounds from endophytic fungi in developing new drugs with multifunction mechanisms to meet human needs is essential. Fungal endophytes produce invaluable bioactive metabolic compounds beneficial to humans with antimicrobial, anticancer, antidiabetic, anti-inflammatory, antitumor properties, etc. Some of these bioactive compounds include pestacin, taxol, camptothecin, ergoflavin, podophyllotoxin, benzopyran, isopestacin, phloroglucinol, tetrahydroxy-1-methylxanthone, salidroside, borneol, dibenzofurane, methyl peniphenone, lipopeptide, peniphenone etc. Despite the aforementioned importance of endophytic fungal metabolites, less information is available on their exploration and pharmacological importance. Therefore, in this review, we shall elucidate the fungal bioactive metabolites from medicinal plants and their pharmacological potential.

show abstract

Section: Pharmacological Effects Of Bioactive Compounds Of Fungal mentioning

confidence: 99%

Pharmacological Potential of Fungal Endophytes Associated with Medicinal Plants: A Review

Adeleke

Babalola

2021

JoF

View full text Add to dashboard Cite

show abstract

“…Endophytic fungi that have been isolated from S. zeylanicum were identified based on their morphological characters, both macroscopically and microscopically (Kumar et al 2019). The morphology of endophytic fungi is presented in Figure 2.…”

Section: Endophytic Fungi Morphological Identificationmentioning

confidence: 99%

Diversity of endophytic fungi from the root bark of Syzygium zeylanicum, and the antibacterial activity of fungal extracts, and secondary metabolite

et al. 2021

View full text Add to dashboard Cite

Abstract. Syarifah, Elfita, Widjajanti H, Setiawan A, Kurniawati AR. 2021. Diversity of endophytic fungi from the root bark of Syzygium zeylanicum, and the antibacterial activity of fungal extracts, and secondary metabolite. Biodiversitas 22: 4572-4582. The decoction of the root bark of Syzygium zeylanicum has been used as traditional medicine, such as for treating pathogenic bacterial infections. Endophytic fungi that live in medicinal plant tissues have a high species diversity and biological activities correlate with their host. Therefore, this study aimed to explore the diversity of endophytic fungi from the root bark of S. zeylanicum and to determine the antibacterial activity of endophytic fungi and their secondary metabolites. In this study, we isolate and identify the endophytic fungi from the root bark of S. zeylanicum, continued by screening their antibacterial activity against two Gram-negative bacteria (Escherichia coli InaCCB5 and Salmonella thypi ATCC1048 and two Gram-positive bacteria (Staphylococcus aureus InaCCB4 and Bacillus subtilis InaCCB1204) by the Kirby-Bauer method. The fungal extract with the highest antibacterial activity proceeded with the isolation and determination of the structure of their bioactive compounds. The isolates were morphologically identified. Isolates that showed strong antibacterial activity were identified by molecular identification. Isolation of bioactive compounds was carried out by chromatographic techniques and the determination of the structure of pure chemical compounds was performed by the spectroscopic analysis. In total, there were 8 isolates of endophytic fungi were obtained from the root bark of S. zeylanicum, namely SZR1 – SZR8. SZR2 isolate has the highest antibacterial activity. Molecular identification through phylogenetic analysis showed that SZR2 isolate had high similarity with Penicillium brefeldianum. Isolation of bioactive compounds from SZR2 produced compound 1 in the form of light yellow crystals which showed strong antibacterial activity against S. typhi, E. coli, and B. subtilis with MIC values of 64 g/mL. Compound 1 was identified as p-hydroxybenzaldehyde, which was also obtained in its host. In conclusion, the endophytic fungus Penicillium brefeldianum produces similar secondary metabolites and antibacterial activity as its host plant.

show abstract

“…Fungi have been found to play important roles in the development of the environment, such as the solubilization of phosphorus (P) and the synthesis of indoleacetic acid (IAA) for plant growth promotion (Kumar et al 2019;Suyal et al 2021a, b). Fungi such Aspergillus can significantly accelerate P solubilization, and arbuscular mycorrhizal fungi (AMF) (e.g., Rhizophagus spp.)…”

Section: Structure and Function Of Rice Rhizosphere Microbiomementioning

confidence: 99%

Structure and Functions of Rice and Wheat Microbiome

Kumar

Juyal

Pandey

et al. 2021

Survival Strategies in Cold-Adapted Microorganisms

Self Cite

View full text Add to dashboard Cite

Plant-associated microorganisms play a crucial role in functioning of agroecosystems through recycling of vital soil nutrients, thus promoting plant growth. Rice (Oryza sativa L.) and wheat (Triticum aestivum L.) are predominant cropping systems for cereal food production. Microbial communities associated with rice and wheat plants confer fitness to the host plants under normal and stressed conditions. Root-associated cold-adapted microorganisms play a crucial role in protecting rice and wheat plants under cold-stressed environment. Advancement in high-throughput sequencing technology has enhanced the

show abstract

Endophytic Fungi: Recent Advances in Identification and Explorations

Cited by 24 publications

References 102 publications

Pharmacological Potential of Fungal Endophytes Associated with Medicinal Plants: A Review

Pharmacological Potential of Fungal Endophytes Associated with Medicinal Plants: A Review

Diversity of endophytic fungi from the root bark of Syzygium zeylanicum, and the antibacterial activity of fungal extracts, and secondary metabolite

Structure and Functions of Rice and Wheat Microbiome

Contact Info

Product

Resources

About