Endometrial carcinoma arising in a bicornuate uterus

Abstract

Endometrial carcinomas arising in a bicornuate uterus are rare, only five case of which have been previously reported. We present a case of endometrial cancer arising in a bicornuate uterus, occurring in a 65-year-old woman. Unlike previously reported cases, our case showed mixed endometrial adenocarcinoma and undifferentiated carcinoma in one horn and focal adenocarcinoma in the other. Adequate tissue sampling of both horns is necessary for accurate diagnosis of malignancy in patients with a bicornuate uterus. Physicians should be aware of the possibility of this abnormality in cases when endometrial cancer is suspected but histology fails to confirm.

Endometrial Cancer in Bicornuate Uterus: Case Report

“…Bicornuat uterusta gelişen endometrial kanser vakası oldukça nadir rapor edilmiştir. Çoğu olguda tek boynuzda endometrium kanseri görülmekte iken, daha nadir olarak her iki uterus boynuzunda endometrium kanserinin geliştiği olgular da sunulmuştur (6,7 …”

Endometrial carcinoma located in the right septate uterus cavity: a case report

“…In the case of septate uterus, the external configuration is normal because the default of resorption of septum between the Müllerian ducts happens at an advanced stage. The correlation between these abnormalities and the incidence of endometrial cancer has never been established and some authors suggest that Mullerian abnormalities can be a protective factor against endometrial cancer by hormone abnormalities signals to estrogen receptors [ 3 ]. The Mullerian abnormalities associated with endometrial cancer are exceptionally described.…”