Endodontic Pathogens Causing Deep Neck Space Infections: Clinical Impact of Different Sampling Techniques and Antibiotic Susceptibility

Poeschl, Paul W.; Crepaz, Valentina; Russmueller, Guenter; Seemann, Rudolf; Hirschl, Alexander M.; Ewers, Rolf

doi:10.1016/j.joen.2011.05.029

Cited by 37 publications

(43 citation statements)

References 29 publications

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“…It follows that Streptococcus species were a significant contributor in predicting those patients requiring surgical intervention in our cohort. This finding is supported by previous studies, which demonstrate a prevalence of Streptococcus species in DNSIs requiring surgical intervention for resolution [6][7][8][9].…”

Section: Discussionsupporting

confidence: 89%

Factors associated with severe deep neck space infections: targeting multiple fronts

Barber

Dziegielewski

Biron

et al. 2014

J of Otolaryngol - Head & Neck Surg

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Objectives: To determine factors predictive of a severe deep neck space infection (DNSI), defined as those requiring surgery and/or postoperative intensive care unit (ICU) admission. To specifically examine dental practices and socioeconomic factors that may contribute to the development of a DNSI. Study design: Retrospective review. Methods: This study was conducted at 2 tertiary care academic referral centers from January 2007 to September 2011. The study was composed of 2 arms: a prospective questionnaire and data collection to identify modifiable risk factors such as dental practices and socioeconomic considerations for a DNSI, and a retrospective review of deep neck space infections to identify commonly associated risk factors predictive of a severe DNSI, requiring surgery and/or postoperative ICU admission.

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Section: Discussionsupporting

confidence: 89%

Factors associated with severe deep neck space infections: targeting multiple fronts

Barber

Dziegielewski

Biron

et al. 2014

J of Otolaryngol - Head & Neck Surg

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“…Therefore, the current data available in the literature is insufficient. Furthermore, anaerobic bacteria are highly susceptible to the adverse effects of using the wrong transport medium for microbiology samples or to poor sampling techniques (Poeschl et al, 2011). In this study we could exclude mistakes in transport, but one has to conclude that isolated bacteria are often also identified as normal oral flora and should not be considered as the cause of the infection.…”

Section: A C C E P T E D Accepted Manuscriptmentioning

confidence: 99%

Oral soft tissue infections: causes, therapeutic approaches and microbiological spectrum with focus on antibiotic treatment

Götz

Reinhart

Wolff

et al. 2015

Journal of Cranio-Maxillofacial Surgery

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“…Staphylococci are commensally of the skin, skin glands, and mucous membranes, both in humans and in animals, that show their pathogenic ability through virulence and a wide range of aggression and toxic factors. 30 S. aureus (Gram-positive coccal bacterium) is often involved in the production of several types of diseases of the oral cavity: stomatitis, orofacial granulomas, 31 periodontitis, [32][33][34][35] periimplant mucositis, 36 endodontic infections, 37 and even tooth decay. 38,39 Micrococcus luteus (gram positive cocci) is considered a non-pathogenic germ usually isolated from the external environment (dust, soil, air, different objects), but it can be frequently found onto the skin, mucous membranes of the nasal cavities and in the oral cavity.…”

Section: Microbiological Evaluation Of Antibacterial Activity Of Membmentioning

confidence: 99%

Amoxicillin-loaded electrospun nanocomposite membranes for dental applications

Furtos

Rivero

Răpuntean

et al. 2016

J. Biomed. Mater. Res.

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Electrospun nanocomposite matrices based on poly(ε-caprolactone) (PCL), nano-hydroxyapatite (nHAp) and amoxicillin (AMX) were designed and investigated for dental applications. nHAp provides good biocompatibility, bioactivity, osteoconductivity, and osteoinductivity properties, and AMX, as antibiotic model, controls and/or reduces bacterial contamination of periodontal defects while enhancing tissue regeneration. A series of polymeric nanocomposites was obtained by varying both the antibiotic and nHAp contents. Fibrous membranes of different compositions were obtained by electrospinning technique, and morphological, thermal, mechanical and surface properties were characterized. The incorporation of AMX seemed to alter the nHAp distribution within the microfibrous matrix. The interaction between AMX and nHAp affected the mechanical performance and modulated the antibiotic release behavior. AMX release profiles presented a burst release that depended on nHAp content, followed by a slow release stage where the drug content (85-100%) was released in 3 weeks. The antimicrobial activity of the AMX-loaded membranes was tested with four bacterial strains depended on both the drug and nHAp contents. Extensive mineralization in simulated body fluid (SBF) was evidenced by SEM/EDX analysis after 21 days. The studied electrospun nanocomposite amoxicillin-loaded membranes could be a promising fibrous-based antibiotic carrier system for dental and tissue engineering applications. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 966-976, 2017.

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Endodontic Pathogens Causing Deep Neck Space Infections: Clinical Impact of Different Sampling Techniques and Antibiotic Susceptibility

Cited by 37 publications

References 29 publications

Factors associated with severe deep neck space infections: targeting multiple fronts

Factors associated with severe deep neck space infections: targeting multiple fronts

Oral soft tissue infections: causes, therapeutic approaches and microbiological spectrum with focus on antibiotic treatment

Amoxicillin-loaded electrospun nanocomposite membranes for dental applications

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