Endodontic irrigant as a root conditioning agent: An in vitro scanning electron microscopic study evaluating the ability of MTAD to remove smear layer from periodontally affected root surfaces

Zia, Afaf; Andrabi, Syed Mukhtar-Un-Nisar; Bey, Afshan; Kumar, Ashok; Fatima, Zareen

doi:10.1016/j.sdj.2014.04.002

Cited by 7 publications

(5 citation statements)

References 23 publications

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“…There is no irrigating solution acts simultaneously on the two component of the smear layer (organic and inorganic). Sodium Hypochlorite combined with EDTA has been used for efficient removal of smear layer (26)(27)(28) . Searching for chelating agent that is more efficient and biocompatible than EDTA has resulted in various solutions being researched over the last few years.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of Apple vinegar as Final Irrigating Solution in Removing Smear Layer Using XP-Endo Finisher File

2020

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Purpose: This study assessed the efficacy of Apple vinegar as final irrigating solution in removing smear layer using XP-Endo Finisher File by scanning microscope. Material and Methods: Fifty single rooted lower premolars were selected and prepared using Universal ProTaper rotary files. Samples were divided into two main groups (I,II) regarding the final rinse used (20 samples each) and control group (10 samples): Group I: rinsed with 17% EDTA, Group II: rinsed with Apple vinegar and Control group: irrigated with sterile saline. Each group was subdivided into two subgroups (A,B) regarding the agitation file. Subgroup A: Conventional irrigation, Subgroup B: agitated with XP Endo Finisher. Samples were grooved longitudinally and smear layer was assessed. Results: no statistically significant difference in the median scores of smear layer produced by 17% EDTA and Apple Vinegar at coronal, middle and apical root levels when conventional irrigation or XP Endo Finisher were used. There was a significant difference between two irrigating techniques at apical level when 17% EDTA used as final rinse, where XP Endo Finisher showed statistically significant lower median score (P≤ 0.05). Conclusions: Apple vinegar presented similar smear layer removal efficiency from intraradicular dentin compared to 17% EDTA when used as final rinse. XP-Endo Finisher is a successful agitation system for removal of smear layer from intraradicular dentin.

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Section: Discussionmentioning

confidence: 99%

Efficacy of Apple vinegar as Final Irrigating Solution in Removing Smear Layer Using XP-Endo Finisher File

2020

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“…In a study by Zia et al ( 2014) [21] carried out on extracted teeth, it was possible to observe the equivalence of EDTA to MTAD Biopure, being more efficient than brine. Another study compared three different formulations of QMix with EDTA and found better efficacy of QMix in removing the smear layer in the apical third and equivalence between the results of the solutions in the middle and cervical thirds, showing a viable alternative to EDTA for the end of irrigation.…”

Section: Mednext Journal Of Medical and Health Sciencesmentioning

confidence: 98%

“…There are contradictory results in the literature regarding the need for Ca(OH)2 removal [17][18][19][20][21]. However, it is well established that residual Ca(OH)2 must be removed because it influences the bonding and sealing of endodontic materials.…”

Section: Mednext Journal Of Medical and Health Sciencesmentioning

confidence: 99%

Clinical significance of the main methods of root canal irrigation in endodontics: a systematic review

Segala,

Tasinaffo,

Castro

2024

MedNEXT

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Introduction: In the context of endodontic treatments, irrigation is one of the most important aspects of the biomechanical preparation of the root canal. The arsenal of irrigation solutions designed for endodontic treatment and commercially available is broad. The choice of the correct solution depends on the combination of the properties of the solution associated with the effects to be obtained with irrigation, according to the clinical condition. Objective: It was to carry out a systematic review of the different endodontic irrigation methods, as well as to show the different clinical indications for use, comparing the effectiveness, biocompatibility, and influence on the dentin surface of irrigation solutions. Methods: The PRISMA Platform systematic review rules were followed. The search was carried out from October to December 2023 in the Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: A total of 115 articles were found, 50 articles were evaluated in full and 41 were included and developed in the present systematic review study. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 10 studies with a high risk of bias and 25 studies that did not meet GRADE and AMSTAR-2. Most studies did not show homogeneity in their results, with X2=57.8%<50%. It was concluded that irrigation plays a fundamental role in the success of endodontic treatment. Although hypochlorite is the most important irrigating solution, no irrigant can perform all of the tasks required by irrigation. A detailed understanding of the mode of action of various solutions is important for optimal irrigation. New developments such as mechanical devices will help promote safe and effective irrigation. Within the limitations of this study, the use of the selfadjusting file system with the combination of EDTA and NaOCl improved Ca(OH)2 removal. The passive ultrasonic irrigation and the self-adjusting file system were more effective in removing Ca(OH)2 from the lateral grooves in the apical parts of the root canal than the EndoVac and conventional syringe irrigation systems.

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“…However, none of these substances can serve as a gold standard for this purpose. [8][9][10] BioPure MTAD (Dentsply, Tulsa Dental, Tulsa, OK, USA) is a product commonly used to remove the smear layer and organic components from an infected root canal system. It is a mixture of a tetracycline isomer, citric acid, and detergent (Tween 80).…”

Section: Introductionmentioning

confidence: 99%

“…It is a mixture of a tetracycline isomer, citric acid, and detergent (Tween 80). 10 QMix (Dentsply, Tulsa Dental Specialties, Johnson City, TN) contains chlorhexidine, EDTA, and a detergent with a slightly alkaline pH. 11 There is insufficient information regarding the comparative effects of new products such as MTAD and QMix on the attachment of fibroblasts to conditioned root dentin.…”

Section: Introductionmentioning

confidence: 99%

Attachment of human periodontal ligament fibroblasts to root dentin conditioned with different endodontic irrigants: An experimental study

Khoshbin

Najafi

Farhadian

et al. 2022

J Dent Res Dent Clin Dent Prospects

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Background. Periradicular surgery is the last treatment option for teeth with persistent periradicular endodontic lesions. This study aimed to assess the adhesion of fibroblasts to root dentin conditioned with ethylenediaminetetraacetic acid (EDTA), MTAD, and QMix. Methods. Twelve dentin discs were fabricated of 6 human single-rooted teeth. Fibroblasts were isolated from the periodontal ligament (PDL) of a premolar tooth. The teeth were healthy and freshly extracted from the socket. The samples were divided into four groups for surface conditioning with (I) EDTA, (II) MTAD, (III) QMix, and the control group. Fibroblasts were cultured on conditioned dentin discs at 37°C, 95% air, and 5% CO2 for 4 hours and then rinsed with PBS three times to eliminate unattached cells from the surface. The mean counts of attached cells were calculated using a Neubauer chamber. Also, the attachment of fibroblasts was evaluated using scanning electron microscopy (SEM). Results. The mean counts of fibroblasts attached to root dentin in EDTA, QMix, MTAD, and control groups were 303±46, 243±41, 213±33, and 347±38, respectively. No significant difference was noted in the number of fibroblasts attached between MTAD, EDTA, and QMix and the control group (P>0.05). Under SEM, the fibroblasts were flat and spindle-shaped, with cytoplasmic processes covering the untreated dentin surface. In the experimental groups, the cells were rounder with fewer processes. All the three groups showed weaker adhesion to dentin compared to the control (untreated dentin) group. Conclusion. Under the limitations of this study, it was concluded that treating the dentin surface with EDTA, MTAD, or QMIX might not be an effective way to improve the adhesion of human PDL fibroblasts.

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Endodontic irrigant as a root conditioning agent: An in vitro scanning electron microscopic study evaluating the ability of MTAD to remove smear layer from periodontally affected root surfaces

Cited by 7 publications

References 23 publications

Efficacy of Apple vinegar as Final Irrigating Solution in Removing Smear Layer Using XP-Endo Finisher File

Efficacy of Apple vinegar as Final Irrigating Solution in Removing Smear Layer Using XP-Endo Finisher File

Clinical significance of the main methods of root canal irrigation in endodontics: a systematic review

Attachment of human periodontal ligament fibroblasts to root dentin conditioned with different endodontic irrigants: An experimental study

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